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| 1 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 2 | A cell cycle regulator potentially involved in genesis of many tumor types 显示文摘 | Kamb A Gruis NA Weaver Feldhaus J | 1994 | Science1994，264，5157： | 2 |
| 3 | Effects of discontinuation of digoxin versus continuation at low serum digoxin concentrations in chronic heart failure显示文摘 | Ahmed A Gambassi G Weaver MT | 2007 | Am J Cardiol2007，100，2： | 1 |
| 4 | R egulation of Insulin Secretion and Blood Glucose Metabolism by Adrenomedullin 显示文摘 | Martinez A Weaver C | 1996 | Endocrinology1996，137，： | 1 |
| 5 | A cell cycle regnlator potenially inrolved in genesis of many tumor typer显示文摘 | Kamb A Gruis NA Weaver FJ | 1994 | Science1994，246，4： | 1 |
| 6 | Marketing your community:image analysis of Norfolk 显示文摘 | Chon K Weaver P A Kim C Y | 1991 | The Cornell H R A Quarterly1991，31，4： | 1 |
| 7 | Social Networking显示文摘 | Weaver A C Morrison B B | 2008 | Computer2008，41，2： | 1 |
| 8 | Flow induced vibrations of a hydraulic valve and their elimination显示文摘 | Weaver D S Adubi F A Kouwen N | 1978 | Journal of Fluids Engineering1978，100，6： | 1 |
| 9 | Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates显示文摘 | Weaver TA Charafeddine AH Agarwal A | 2009 | Nat Med2009，15，7： | 1 |
| 10 | Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat显示文摘 | SZYF M WEAVER I C CHAMPAGNE F A | 2005 | Frontiers in Neuroendocrinology2005，26，34： | 1 |
| 11 | 查看详情显示文摘 | Cole A C Jensen J L Ntai I Tran K L T Weaver K J Forbes D C Davis J H Jr | | 0，，： | 1 |
| 12 | The targets of vitamin D depend on the differentiation and activation status of CD4positive T cells显示文摘 | Mahon BD Wittke A Weaver V | 2003 | J Cell Biochem2003，89，5： | 1 |
| 13 | The impact of new biologicals in the treatment of rheumatoid arthritis 显示文摘 | WEAVER A L | 2004 | Rheumatology2004，43，3： | 1 |
| 14 | Mannitol-induced acute renal failure显示文摘 | Weaver A | 1987 | Nephron, 1987,45(3):2331987，45，3： | 1 |
| 15 | The targets of vitamin D depend on the differentiation and activation status of CD4 positive T cells显示文摘 | Mahon B D Wittke A Weaver V | 2003 | J Cell Biochem2003，89，5： | 1 |
| 16 | An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization显示文摘 | Weaver A Goncalves da Silva A Nuttall RK | 2005 | FASEB2005，19，： | 1 |
| 17 | Robotie radical hysterectomy:comparison with laparoscopy and laparotomy显示文摘 | Magrina J F Kho R M Weaver A L | | 0，，01： | 1 |
| 18 | Think tanks in the US media显示文摘 | Rich A Weaver R K | 2000 | The Harvard International Journal of Press/Politics2000，5，4： | 1 |
| 19 | The impact of social media on destinationbranding: Consumer-generated videos versus destination marketer-generatedvideos 显示文摘 | Lim Y Chung Y Weaver P A | 2012 | Journal of Vacation Marketing2012，18，3： | 1 |
| 20 | Robotic radical hysterectomy:comparison with laparoscopy and laparotomy显示文摘 | MAGRINA J F KHO R M WEAVER A L | 2008 | Gynecol Oncol2008，109，1： | 1 |
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