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| 1 | Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease显示文摘AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: Vitamin B6, folate, vitamin B12, and fasting plasma homocysteine levels were measured in 51 consecutive adults with celiac disease [median (range) age 56 (18-63) years; 40% men, 26 (51%) had villous atrophy, and 25 (49%) used B-vitamin supplements] and 50 healthy control individuals matched for age and sex. Finally, the C677T polymorphism of 5,10-methylene tetrahydrofolate reductase (MTHFR) was evaluated in 46 patients with celiac disease and all control individuals. RESULTS: Patients with celiac disease and using vitamin supplements had higher serum vitamin B6 (P = 0.003),folate (P < 0.001), and vitamin B12 (P = 0.012) levels than patients who did not or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively). Lower plasma homocysteine levels were found in patients using vitamin supplements than in patients who did not (P = 0.001) or healthy controls (P = 0.003). However, vitamin B6 and folate, not vitamin B12, were significantly and independently associated with homocysteine levels. Twenty-four (48%) of 50 controls and 23 (50%) of 46 patients with celiac disease carried the MTHFR thermolabile variant T-allele (P = 0.89). CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. | Muhammed Hadithi Chris JJ Mulder Frank Stam Joshan Azizi J Bart A Crusius Amado Salvador Pea Coen DA Stehouwer Yvo M Smulders | 2009 | World Journal of Gastroenterology2009，15，8： | 3 |
| 2 | Impairment of Predictive Saccades in Schizophrenia 显示文摘 | Krebs M O Gut - Fayand A Amado I | 2001 | Neuroreport2001，12，3： | 1 |
| 3 | Morphology and characterization of laser clad composite NiCrBSi-WC coatings on stainless steel显示文摘 | TOBAR M J ALVAREZ C AMADO J M RODRIGUEZ G YANEZ A | 2006 | Surface & Coatings Technology2006，200，： | 1 |
| 4 | Delayed ACTH response to human cortieotropin reseasing hormone during eardiopulmonary bypass under diazepam-high dose fentanyl anaesthesia显示文摘 | Amado J A Diago M C | 1994 | Anaesthesia1994，49，： | 1 |
| 5 | Crack free tungsten carbide reinforced Ni (Cr) layers obtained by laser cladding 显示文摘 | Amado J M Tobar M J Y6f:ez A | 2011 | Phys Procedia2011，12，338： | 1 |
| 6 | Double versus single renal allografts from agel donors 显示文摘 | Amado A jose mara M Juan Carlos H | 2000 | Transplantation2000，69，10： | 1 |
| 7 | Regulation of muscle hydration upon hypo-or hyper-osmotic shocks:Differences related to invasion of the freshwater habitat by decapod crustaceans显示文摘 | FREIRE C A SOUZA-BASTOS L R AMADO E M | 2013 | J Exp Zool A Ecol Genet Physiol2013，319，6： | 1 |
| 8 | Crack free tungsten carbide reinforced Ni(Cr) layers obtained by laser cladding显示文摘 | AMADO J M TOBAR M J YANEZ A | 2011 | Phys Proc2011，，12： | 1 |
| 9 | Virulence gene expression in Malasseziaspp from individuals with seborrheic dermatitis显示文摘 | Patio-Uzcátegui A Amado Y Cepero de García M | | 0，，10： | 1 |
| 10 | Integrating the data envelopment analysis and the balanced scorecard approaches for enhanced performance assessment显示文摘 | AMADO A F SANTOS S P MARQUES P M | 2012 | Omega2012，，40： | 1 |
| 11 | Separation of 8 Aminonaphthalene-l,3,6-trisulfonic Acid-Labeled Neutral and Sialylated N-Linked Complex Oligosaccharides by Capillary Electrophoresis显示文摘 | Kbckow A Amado R Widmer H M | | 0，，01： | 1 |
| 12 | Crack free tungsten carbide reinforced Ni (Cr) layers obtained by laser cladding 显示文摘 | Amado J M Tobar M J Y6fiez A | 2011 | Physics Procedia2011，12，： | 1 |
| 13 | Crack free tungsten carbide reinforced Ni ( Cr ) layers obtained by laser cladding 显示文摘 | Amado J M Tobar M J Ydfiez A | 2011 | Physics Procedia2011，12，1： | 1 |
| 14 | Contrast-enhancement multidetector compu ted tomography viability imaging after myocardial infarction characterization of myocyte death, microvascular obstruction and chronic scar显示文摘 | Lardo A C Cordeiro M A S Silva C Amado L C George R T Saliaris A P | 2006 | Circulation2006，113，： | 1 |
| 15 | Materials per- spective of polymers for additive manufacturing with selective laser sintering 显示文摘 | SCHMID M AMADO A WEGENER K | 2014 | J Mater Res2014，29，17： | 1 |
| 16 | The detection of human papillomavirus in papillomas of the larynx and tonsils through immunohistochemistry and DNA in situ hybridization显示文摘 | Lopez Amado M Garcia Caballero T Lozano Ramirez A | 1997 | Ann Otorhinolaryngollbero Am1997，24，3： | 1 |
| 17 | Complementary pathways of dissolved organic carbon removal pathways in clear-water Amazonian ecosystems: photochemical degradation and bacterial uptake显示文摘 | Amado A M Farjalla V F Esteves F D A | 2006 | FEMS Microbiology Ecology2006，56，1： | 1 |
| 18 | DeIayed ACTH response to hu man corticotropin releasing hormone during cardiopulumonary bypass under diazepam-high dose fentanyl anassthesia显示文摘 | AMADO J A DIAGO M C | 1994 | Anaesthesia1994，49，： | 1 |
| 19 | Integrating the data envelopment analysis and the balanced scorecard approaches for enhanced performanceassessment显示文摘 | Amado C A F Santos S P Marques P M | 2012 | O- mega-International Journal of Management Science2012，40，3： | 1 |
| 20 | Use of hy-brid chitosan membranes and N1E-115 cells for promoting nerve regeneration in an axonotmesis rat model显示文摘 | AMADO S SIMOES M J ARMADA D A | 2008 | Biomate- rials2008，29，33： | 1 |
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