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308篇 您的检索式:作者名="APTE S"
    题名 作者 年代 出处 被引量
1Pancreatic cancer and its stroma: A conspiracy theory显示文摘Pancreatic cancer is characterised by a prominent desmoplastic/stromal reaction that has received little attention until recent times. Given that treatments focusing on pancreatic cancer cells alone have failed to significantly improve patient outcome over many decades, research efforts have now moved to understanding the pathophysiology of the stromal reaction and its role in cancer progression. In this regard, our Group was the first to identify the cells(pancreatic stellate cells, PSCs) that produced the collagenous stroma of pancreatic cancer and to demonstrate that these cells interacted closely with cancer cells to facilitate local tumour growth and distant metastasis. Evidence is accumulating to indicate that stromal PSCs may also mediate angiogenesis, immune evasion and the well known resistance of pancreatic cancer to chemotherapy and radiotherapy. This review will summarise current knowledge regarding the critical role of pancreatic stellate cells and the stroma in pancreatic cancer biologyand the therapeutic approaches being developed to target the stroma in a bid to improve the outcome of this devastating disease.Zhihong Xu Srinivasa P Pothula Jeremy S Wilson Minoti V Apte 2014World Journal of Gastroenterology2014,20,32:10
2Comparative toxicity of anoparticulate ZnO,bulk ZnO,and ZnCl2 to a freshwater microalga(Pseudokirchneriella subcapitata);the importance of particle solubility显示文摘Franklin N M Rogers N J Apte S C 2007Enviro nmentalScience and Technology2007,41,24:1
3Exacerbation of Acanthamoeba keratitis in animals treated with anti-macrophage inflammatory protein 2 or antineutrophil antibodies显示文摘Hurt M Apte S Leher H Howard K Niederkorn J Alizadeh H 2001Infect Immun2001,69,:1
4The economics of using plug-in hybrid electric vehicle battery packs tbr grid storage 显示文摘PETERSON S B WHITACRE J F APT J 2010Journal of Power Sources2010,195,8:1
5The economics of using plug-in hybrid electric vehicle battery packs for grid stor- age 显示文摘Peterson S B Whitacre J F Apt J 2010Journal of Power Sources2010,195,8:1
6Lithium-ion battery cell degradation resulting from realistic vehicle and vehicle-to-grid utilization显示文摘Peterson S Apt J Whitacre J 2010Journal of Power Source2010,195,8:1
7Arsenic,antimony and selenium speciation during a spring phytoplankton bloom in a closed experimental ecosystem显示文摘APTE S C HOWARD A G 1986Marine Chemistry1986,20,:1
8Impaired endochondral ossification and angiogenesis in mice deficient in membrane - type matrix metalloproteinase I显示文摘ZHOU Z APTE S S SOININEN R 2000Proc Natl Acad Sci U S A2000,97,8:1
9Characterization of PLGA microspheres for the controlled delivery of IL-1 for tumor immunotherapy 显示文摘 Apte RN Cohen S 1997J Control Release1997,43,23:1
10Engineering of Deinococcns radiodnrans Rl for bioprecipitation of uranium from dilute nuclear waste显示文摘Appukuttan D Rao A S Apte S K 2006Appl Environ Microbiol2006,72,12:1
11The biotic ligand model: A his- torical overview显示文摘Paquin PR Gorsuch JW Apte S 2002Comp Biochem Physiol C2002,133,:1
12Characterization of PLGA microspheres for the controlled delivery of IL-1 for tumor immunotherapy显示文摘Chen L Apte RN Cohen S 1997J Controlled Release1997,43,261:1
13Investigation of Paraffin Deposition During Multi-phase Flow in Pipelines and Wellbores-Part 1: Ex-periments显示文摘Mandar S Apte Hong-Quan Zhang Michael Volk etal 2002Journal of Energy Resources Technol-ogy2002,124,3:1
14Unsteady flow evolution in porous chamber with surface mass injection显示文摘Apte S V Yang V 2002AIAA Journal2002,39,8:1
15Effect of tumor necrosis factor α and intercelluar adhesion molecule-1 expression on immunogenicity of murine liver cells in mice显示文摘Bumgardner GL Li J Apte S Heininger M Frankel WL 1998Hepatology1998,28,2:1
16Nrampl promotes efficient macrophage recycling of iron follow- ing erythrophagocytosis in vivo显示文摘Soe-Lin S Apte S S Andriopoulos B 2009Proc Natl Acad Sci USA2009,06,14:1
17Changes in orbital dimensions following enucleation 显示文摘Apt L lsenberg S 1973Arch Ophthalmol1973,90,:1
18Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22显示文摘APTE S S MATTEI M G OLSEN B R 1994Genomics1994,19,1:1
19Desmoplastic reaction in pancreatic cancer:role of pancreatic stellate cells显示文摘Apte MV Park S Phillips PA 2004Pancreas2004,29,3:1
20Factors associated with improved toxicity and tolerability of intraperitoneal chemotherapy in advanced - stage epithelial ovarian cancers 显示文摘Teefey P Bou Zgheib N Apte S M 2013Am J Obstet Gynecol2013,208,6:1
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