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| 1 | 糖耐量低减和空腹血糖受损:定义及干预的现状显示文摘由国际糖尿病联盟 (IDF)召集的本次研讨会是为了考察有关糖耐量低减 (IGT)和空腹血糖受损 (IFG)相关的糖尿病和心血管疾病 (CVD)风险的最新文献 ,力图回答三个问题 :(1 )目前的IGT和IFG的定义是否合适 ;(2 )IFG和IGT是危险因子 (riskfactor)、危险标志 (riskmarker)还是疾病 (disease) ;(3)对 :IFG和IGT人群应该采取怎样的干预措施 (如果有的话 ) ?①引起空腹血糖 (FPG)和口服葡萄糖耐量试验(OGTT) 2h血糖 (2hPG)升高的因素并不相同 ,肝脏葡萄糖输出增加和早期胰岛素释放缺陷是前者的特点 ,而外周胰岛素抵抗是后者的显著特征。因此 ,IFG和IGT之间的一致性是有限的。迄今所有的患病率调查发现 ,只有不到一半的IFG人群有IGT ,更少的IGT人群 (2 0 %~ 30 % )有IFG。②大多数的人群研究表明 ,IGT的患病率远高于IFG ,二者的临床表现和性别分布也有差异。IFG在男性更为常见 ,IGT在女性稍微增多。IFG的患病率倾向在中年达到高峰 ,而IGT的患病率逐渐增加直到老龄。③IFG和IGT都与发生糖尿病的风险显著增加有关 ,而最大的风险在于同时具有IFG和IGT的人群。由于在多数人群IGT比IFG更常见 ,所以对于筛查糖尿病高危人群 ,IGT的敏感性较高 (特异性稍差 )。在多数人群 ,60 %的糖尿病人大约 5年前已有IGT或IFG ,另外 | Unwin N Shaw J Zimmet P Alberti KGMM 金文胜 潘长玉 | 2003 | 中华内分泌代谢杂志2003，19，1： | 92 |
| 2 | Extraordinary evanescent field confinement waveguide sensor for mid-infrared trace gas spectroscopy显示文摘Nanophotonic waveguides are at the core of a great variety of optical sensors.These structures confine light along defined paths on photonic chips and provide light-matter interaction via an evanescent field.However,waveguides still lag behind free-space optics for sensitivity-critical applications such as trace gas detection.Short optical pathlengths,low interaction strengths,and spurious etalon fringes in spectral transmission are among the main reasons why on-chip gas sensing is still in its infancy.In this work,we report on a mid-infrared integrated waveguide sensor that successfully addresses these drawbacks.This sensor operates with a 107%evanescent field confinement factor in air,which not only matches but also outperforms free-space beams in terms of the per-length optical interaction.Furthermore,negligible facet reflections result in a flat spectral background and record-low absorbance noise that can finally compete with free-space spectroscopy.The sensor performance was validated at 2.566μm,which showed a 7 ppm detection limit for acetylene with only a 2 cm long waveguide. | Marek Vlk Anurup Datta Sebastián Alberti Henock Demessie Yallew Vinita Mittal Ganapathy Senthil Murugan Jána Jagerská | 2021 | Light(Science & Applications)2021，10，2： | 9 |
| 3 | Global and societal implications of the diabetes epidemic显示文摘 | Zimmet P Alberti KG Shaw J | 2001 | Nature2001，414，6865： | 1 |
| 4 | Treatment of extrahepatic portal hypertension in children by mesenteric-to-left portal vein bypass:a new physiological procedure显示文摘 | de Ville de Goyet J Alberti D Falchetti D | 1999 | Eur J Surg1999，165，8： | 1 |
| 5 | Microbial mineralization of biochar andwheat straw mixture in soil: A short-term study显示文摘 | Zavalloni C Alberti G Biasiol S Vedove GD Foraasier F Liu J Peressotti A | 2011 | AppliedSoil Ecology2011，50，： | 1 |
| 6 | Global and societal implications of the diabetes epidemic显示文摘 | Zimmet P Alberti KG Shaw J | | 0，，6865： | 1 |
| 7 | The metabolic syn-drome-a new worldwide definition 显示文摘 | Alberti KG Zimmet P Shaw J | 2005 | Lancet?2005，366，9491： | 1 |
| 8 | International Diabetes Federation:acon- sensus on type 2 diabetes prevention显示文摘 | Alberti K Zimmet P Shaw J | 2007 | Diabetic Medicine2007，24，5： | 1 |
| 9 | The metabolic syndrome-a new worldwide definition显示文摘 | Alberti KG Zimmet P Shaw J | | 0，，9491： | 1 |
| 10 | Global and societal implications of the diabetes epidemic显示文摘 | Zimmet P Alberti KG Shaw J | 2001 | Nature2001，414，： | 1 |
| 11 | The metabolic syndrome--a new worldwide definition显示文摘 | ALBERTI K G ZIMMET P SHAW J | 2005 | Lancet2005，366，9491： | 1 |
| 12 | Carbon dynamics of a ponderosa pine plantation following a thinning treatment in the northern Sierra Ne- vada 显示文摘 | Campbell J Alberti G Martin J | 2009 | Forest Ecology and Management2009，257，： | 1 |
| 13 | International Diabetes Federation:a consensus on type 2 diabetes prevention显示文摘 | Alberti KG Zimmet P Shaw J | 2007 | Diabet Med2007，24，： | 1 |
| 14 | Carbon dynamics of a ponderosa pine plantation following a thinning treatment in the northern Sierra Nevada 显示文摘 | Campbell J Alberti G Martin J | 2009 | Forest Ecology and Management2009，257，： | 1 |
| 15 | Bone marrow stromal cells produce nerve growth factor and glial cell line-derived neurotrophic factors显示文摘 | Garcia R Aguiar J Alberti E | 2004 | Biochem Biophys Res Commun2004，316，3： | 1 |
| 16 | The concept and technique of the split liver in clinical transplantation显示文摘 | Otte JB de-viae-de Goyet J Alberti D | 1990 | Surgery1990，107，6： | 1 |
| 17 | The metabolic syndrome-a newworldwide definition显示文摘 | Alberti KG Zimmet P Shaw J | 2005 | Lancet2005，366，： | 1 |
| 18 | Global and societal implications of the diabetes epidemic显示文摘 | ZLMMET P ALBERTI KG SHAW J | 2001 | Nature2001，414，： | 1 |
| 19 | The metabolic syndrome-a new worldwide definition 显示文摘 | Alberti KG Zimmet P Shaw J | 2005 | Lancet2005，366，9491： | 1 |
| 20 | Pyrazolopyridines as p38 kinase inhibitors显示文摘 | Stevens K L Jung D V Alberti M J | 2005 | Organic Letters2005，7，21： | 1 |
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