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| 1 | Effects of partial portal vein arterialization on the hilar bile duct in a rat model显示文摘BACKGROUND: Liver revascularization is frequently required during the enlarged radical operation for hilar cholangio carcinoma involving the hepatic artery. Researchers have carried out a number of experiments applying partial porta vein arterialization (PVA) in clinical practice. In this study we aimed to establish a theoretical basis for clinical application o partial PVA and to investigate the effects of partial PVA on ra hilar bile duct and hepatic functions. METHODS: Thirty rats were randomly and equally assigned into 3 groups: control (group A), hepatic artery ligation+bile duct recanalization (group B), and partial PVA+bile duc recanalization (group C). Proliferation and apoptosis o rat hilar bile duct epithelial cells, arteriolar counts of the peribiliary plexus (PBP) of the bile duct wall, changes in serum biochemistry, and pathologic changes in the bile duc were assessed 1 month after operation. RESULTS: The proliferation of hilar bile duct epithelial cells in group B was greater than in groups A and C (P<0.01). No apoptotic hilar bile duct epithelial cells were detected in any of the groups. The PBP arteriolar counts of the hilar bile duc wall were similar in groups A and C (P>0.05), but the coun was lower in group B than in group A (P<0.01). No statistically significant differences in alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and albumin were found in the 3 groups. The gamma-glutamyltransferase value was higher in group B than in groups A and C (P<0.01) The hepatic tissues of groups A and C showed no significan abnormality. Chronic inflammatory changes in the hilar bile duct walls were observed only in group B. CONCLUSION: Partial PVA can restore the arterial blood supply of the hilar bile duct and significantly extenuate the injury to hilar bile duct epithelial cells resulting from hepatic artery ligation. | Shao-Hua Guo, Chong-Hui Li,Yong-Liang Chen, Jian-Ning Song,Ai-Qun Zhang and Cheng Zhou Department of Hepatobiliary Surgery (Guo SH, Li CH, Chen YL, Song JN, Zhang AQ and Zhou C) and Department of Surgical Oncology (Guo SH), General Hospital of PLA, Beijing 100853, China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 8 |
| 2 | Phase Relations in TiAl+Nb System显示文摘The microstructures and phases of ternary TiAl+Nb alloys containing 50-60 at.-%Al, 0-21 at.-%Nb have been studied using transmission electron microscopy (TEM) and X-ray powder diffraction. The phases present in the alloys and their distribution were found to be a sensitive function of composition. The phase relations between γ-TiAl and γ1 (a new ordered ternary intermetallic compound based on γ-TiAl) were determined. Essentially single γ phase was determined for alloys with relativety low Nb content (≤10 at.-%Nb). the γ1 phase was determined to exist in the composition range containing higher Nb contents (15-21 at.-%Nb). Between γ and γ1 phases, with intermediate Nb contents there is a transitional phase γ1 (a superstructure of γ-TiAl). As for the influence of Al concentration on the phase relations. the γ1 phase was inclined to form in the alloys with relatively high Al contents. The ordering transformation of γ, to γ1 is a continuous ordering process and the transition may be second order. | Jingguo WANG Guoliang CHEN and Zuqing SUN (State Key Lab. for Advanced Metal Materials, University of Science and Technology Beijing, Beijing, 100083, China)Hengqiang YE (Lab. of Atomic Imaging of Solids, Institute of Metal Research, Academia Sinica, Sh | 1994 | Journal of Materials Science & Technology1994，10，5： | 3 |
| 3 | Image- guided surgical navigation in otology and neurotology 显示文摘 | | | Am J Otol0，20，5： | 1 |
| 4 | 显示文摘 | Simpson SH Gamble JM Mereu L etal Effect of aspirin does on mortality and cardiovascular events in people with diabetes:a meta- analysis | 2011 | J Gen Inter Med2011，26，11： | 1 |
| 5 | Clustering algorithm based selective ensemble显示文摘 | Li G Z Yang J Kong A SH and Chert N Y | 2004 | Journal of Fudan University(Natural Science)2004，05，69： | 1 |
| 6 | Extrahepatic bile duct angulation by Ttube:The elbow sign显示文摘 | Lee SH and Burhenne HJ | 1991 | Gastrointest Radiol1991，16，： | 1 |
| 7 | Grafted and ungrafted labial gingival recession in pediatric orthodontic patients:effect of retraction and inflammation 显示文摘 | Nygan PW Burch JG and Wei SH | 1991 | Quintessence Int1991，22，2： | 1 |
| 8 | Report of two cases显示文摘 | Kim S Baik MW Yoo SH Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique | 2007 | J Neurosurg2007，106，5： | 1 |
| 9 | Salmonellae isolated from domestic meat waste 显示文摘 | Durrant DS and Beatson SH | 1981 | J Hyg( Lond)1981，86，： | 1 |
| 10 | A salt-induced chloroplast protein in Dunaliella salina (Chlorophyta)显示文摘 | Lu Sh Zhang X N Li P Y Liu Zh L and Xia Zh H | 1996 | Phycology1996，32，： | 1 |
| 11 | Chemotherapy-induced apoptosi显示文摘 | Budihardjo II and SH Kaufmann | 1997 | Adv Pharmacol1997，41，： | 1 |
| 12 | Characterization of a mitochondrial DNA deletion in patients with mitochondrial myopathy显示文摘 | Kim SH and Chi JG | 1997 | Mol Cells1997，7，： | 1 |
| 13 | Fabrication of Microcellular Ceramics Using Gaseous Carbon Dioxide显示文摘 | Kim YW and Kim SH | 2003 | J Am Ceram Soc2003，86，12： | 1 |
| 14 | Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression显示文摘 | Chang SH Liu CH Conway R Han DK Nithipatikom K Trifan OC Lane TF and Hla T | 2004 | Proc Natl Acad Sci USA2004，101，： | 1 |
| 15 | Studies on sound-induced epilepsy in mice显示文摘 | SH Chung and MS Johnson | 1984 | Proc R Soc Lond B Biol Sci1984，221，1223： | 1 |
| 16 | Ginsenoside Rh2 induces apoptosis via activation of caspase-1 and-3 and up-regulation of Bax in human neuroblastoma显示文摘 | KIM YS AND JIN SH | 2004 | Arch Pharm Res2004，27，8： | 1 |
| 17 | Fabrication of open-cell, microcellular silicon carbide ceramics by crabothermal reduction 显示文摘 | Kim YW and Kim SH | 2005 | J Am Ceram Soc2005，88，10： | 1 |
| 18 | Seasonal variation of earthworm abundances and biomass in natural forests and plantations(North of Iran) 显示文摘 | Mohammadnezhad Kiasari Sh Sagheb-Talebi Kh Rahmani R and Ghasemi Chapi O | 2009 | Cas J Environ Sci2009，7，： | 1 |
| 19 | The search for the hemangioblast 显示文摘 | Mikkola HK and Orkin SH | 2002 | J Hematother Stem Cell Res2002，11，1： | 1 |
| 20 | Glass fiber coating for optimum mechanical properties of vinyl ester composites 显示文摘 | SH Saidpour and MOW Richardson | 1997 | Composites1997，28，： | 1 |
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