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70篇 您的检索式:作者名="Appelboom"
    题名 作者 年代 出处 被引量
1Role of the complement cascade in cerebral aneurysm formation,growth,and rupture显示文摘Rupture of intracranial aneurysms is the most common cause of nontraumatic subarachnoid hemorrhage,but the intricate neuroinflammatory processes which contribute to aneurysm pathophysiology are not well‑understood.Mounting evidence has implicated the complement cascade in the progression of aneurysms from their formation to rupture.In this article,we identify and review studies that have sought to determine the role of the complement system in the aneurysm pathogenesis.The studies were generally conducted by immunhistological analyses on aneurysm tissue collected intraoperatively,and multiple components of the complement cascade and its modulators were identified in specific regions of the aneurysm wall.The results of the studies suggest that the complement cascade is locally upregulated and disinhibited in the perianeurysmal environment,and that it contributes to chronic as well as acute immunological damage to the aneurysm wall.In the future,understanding the mechanisms at work in complement‑mediated damage is necessary to leading the development of novel therapies.Blake E.S.Taylor Geoff Appelboom Robert Zilinyi Ariana Goodman David Chapel Melissa LoPresti Edward Sander Connolly Jr. 2015Neuroimmunology and Neuroinflammation2015,2,1:2
2Evaluation of intraventricular hemorrhage assessment methods for predicting outcome following intracerebral hemorrhage显示文摘Hwang B Y Bruce S S Appelboom G 2012Neurosurg2012,116,1:1
3Infecton is not specific for bacterial osteoarticular infective pathology显示文摘Dumarey N Blocklet D Appelboom T 2002Eur J Nucl Med2002,29,:1
4Traumatic brain injury in pediatric patients: evidence for the ef- fectiveness of decompressive surgery 显示文摘Appelboom G Zoller SD Piazza MA 2011Neurosurg Focus2011,31,5:1
5Endoscope integratedICG technology:first application during intracranial aneurysmsurgery 显示文摘Bruneau M Appelboom G Rynkowski M 2013Neurosurgical Review2013,36,:1
6Treatment with infliximab restores normal aquaporin 5 distribution in minor salivary glands of patients with Sjtgren's syndrome 显示文摘Steinfeld SD Appelboom T Delporte C 2002Arthritis Rheum2002,46,8:1
7Infliximab in patients with primary SjSgren's syndrome: a pilot study显示文摘Steinfeld SD Demols P Salmon I Appelboom T 2001Arthritis Rheum2001,44,:1
8Treatment with infliximab restores normal aquaporin 5 distribution in minor salivary glands of patients with Sjgren's syndrome显示文摘Steinfeld SD Appelboom T Delporte C 2002Arthritis Rheum2002,46,8:1
9Endoscope integrate ICG technology :First application during intracranial aneurysm surgery 显示文摘Bruneau M Appelboom G 2013Neuro-surg Rev2013,36,:1
10Bedside use of a dual aortic balloon occlusion for the treatment of cerebral vasospasm显示文摘Appelboom G Strozyk D Hwang BY 2010Neurocrit Care2010,13,3:1
11Traumatic brain injury in pediatric patients:evidence for theeffectiveness of decompressive surgery显示文摘Appelboom G Zoller SD Piazza MA 2011Neurosurg Focus2011,31,5:1
12Management practices for sediment reduclion from forest roads in the coastal plains 显示文摘APPELBOOM T W CHESCHEIR G M SKAGGS R W 2002Transactions of ASAE2002,45,2:1
13Comparison of the onset and intensity of action of intramuscular meloxicam and oral meloxicam in patients with acute sclatica显示文摘Auvinet B Ziller R Appelboom T 1995Clin Ther1995,17,:1
14Clinical trials in decompressive craniectomy after severe diffuse traumatic brain injury显示文摘Appelboom G Piazza M Zoller SD 2013World Neurosurg2013,80,5:1
15The promise ofwearable activity sensors to define patient recovery 显示文摘Appelboom G Yang A Connolly E 2014J ClinNeurosci2014,21,7:1
16Aquaporin-4 gene variant independently associated with oedema after intraccerebral haemorrhage显示文摘Appelboom G Bruce S Duren A 2015Neurological Research2015,37,8:1
17Management practices for sediment reduction from forest roads in the coastal plain 显示文摘Appelboom T W Cheschier G M Skaggs R W 2002Transaction of the ASAE2002,45,2:1
18Smart wearable body sensors for patient self-assessment and monitoring 显示文摘Appelboom G Camacho E Abraham M et ol 2014Arch Public Health2014,72,1:1
19Evaluation of intraventric ular hemorrhage assessment methods for predicting outcome following intracerebral hemorrhage 显示文摘Hwang B Y Bruce S S Appelboom G 2012J Neurosurg2012,116,1:1
20Clinical grading scales in intracerebral hemorrhage显示文摘Wang BY Appelboom G Kellener CP 2010Neurocrit Care2010,13,1:1
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