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| 1 | Handheld high-throughput plasmonic biosensor using computational on-chip imaging显示文摘We demonstrate a handheld on-chip biosensing technology that employs plasmonic microarrays coupled with a lens-free computational imaging system towards multiplexed and high-throughput screening of biomolecular interactions for point-of-care applications and resource-limited settings.This lightweight and field-portable biosensing device,weighing 60 g and 7.5 cm tall,utilizes a compact optoelectronic sensor array to record the diffraction patterns of plasmonic nanostructures under uniform illumination by a single-light emitting diode tuned to the plasmonic mode of the nanoapertures.Employing a sensitive plasmonic array design that is combined with lens-free computational imaging,we demonstrate label-free and quantitative detection of biomolecules with a protein layer thickness down to 3 nm.Integrating large-scale plasmonic microarrays,our on-chip imaging platform enables simultaneous detection of protein mono-and bilayers on the same platform over a wide range of biomolecule concentrations.In this handheld device,we also employ an iterative phase retrieval-based image reconstruction method,which offers the ability to digitally image a highly multiplexed array of sensors on the same plasmonic chip,making this approach especially suitable for high-throughput diagnostic applications in field settings. | Arif E Cetin Ahmet F Coskun Betty C Galarreta Min Huang David Herman Aydogan Ozcan Hatice Altug | 2014 | Light(Science & Applications)2014，3，1： | 6 |
| 2 | 西地那非能改善慢性肾功能衰竭大鼠的勃起功能显示文摘勃起功能障碍(ED)和慢性肾衰竭(CRF)之间的关系已在几个研究中被报道。本研究旨在探讨长期使用西地那非是否能增强CRF诱导大鼠的勃起能力。此外,我们评估了该治疗对某些分子的影响,这些分子被认为在勃起生理学及CRF相关的ED中起关键作用。研究分三组:(1)年龄配对的对照组,(2)CRF诱导的大鼠模型组,(3)CRF诱导大鼠给予西地那非慢性给药组((5 mg /kg口服6周[CRF诱导后6周开始治疗])。 3个月时,所有的动物进行海绵体神经刺激(CNS)来评估勃起功能。在所有大鼠组进行,阴茎组织晚期糖化终产物(AGE的) / 5-羟甲基-2-糠醛,丙二醛(MDA),cGMP(ELISA),诱导型一氧化氮合酶(iNOS)和神经元型NOS(nNOS的)(Western印迹)分析。CRF诱导大鼠与对照组相比,勃起功能有显著降低(P 〈0.05)。CRF诱导大鼠西地那非治疗组(第3组),海绵体内压(ICP)和曲线下面积的
增加量,大于CRF诱导大鼠组(第2组)。此外,西地那非治疗下调了AGE,MDA和iNOS的水平,同时保持了CRF诱导阴茎组织的nNOS和cGMP含量。西地那非治疗组AGE,MDA,iNOS的下降和nNOS,cGMP水平的增加,增加了ICP和海绵体神经刺激(CNS)的总ICP,使得CRF诱导大鼠阴茎勃起功能得到改善。本研究的结果表明慢性西地那非给药对CRF诱导大鼠的勃起功能有治疗效果。 | Nilgun Gurbuz Arif Kol Tumay Ipekci Erhan Ates Asli Baykal Mustafa F Usta | 2015 | Asian Journal of Andrology2015，17，5： | 3 |
| 3 | Appropriate and inappropriate use of fresh frozen plasma显示文摘 | Moiz B Arif F M Hashmi K Z | 2006 | J Pak Med Assoc2006，56，8： | 1 |
| 4 | Thermal stress developed during the laser cutting process:consideration of different materials显示文摘 | A F M Arif B S Yilhas | 2008 | The International Journal of Advanced Manufacturing Technology2008，37，78： | 1 |
| 5 | Laser welding of low carbon steel and thermal stress analysis 显示文摘 | Yilbas B S Arif A F M Abdul Aleem B J | 2010 | Optics & Laser Technology2010，42，5： | 1 |
| 6 | Cemented carbide cutting tool: Laster processing and thermal stress analysis显示文摘 | YILBAS B S ARIF A F M KARATAS C AHSAN M | 2007 | Applied Surface Science2007，253，： | 1 |
| 7 | Numerical prediction of plastic deformation and residual stress induced by laser shock processing 显示文摘 | ARIF A F M | 2003 | Journal of Materials Processing Technology2003，136，1： | 1 |
| 8 | Laser shock processing: modeling of evaporation and pressure field developed in the laser- produced cavity显示文摘 | B S Yilbas S B Mansoor A F M Arif | 2009 | Int J Adv Manuf Technol2009，42，34： | 1 |
| 9 | A preliminary study of dexamethasone against ischernia/reperfusion liver injury in rats显示文摘 | Amr A F Mahmoud H E Arif M U | | 0，，02： | 1 |
| 10 | Robust electrocardiogram (ECG) beat classification using discrete wavelet transform 显示文摘 | MINHAS F U ARIF M | 2008 | Phys- iol Meas2008，29，5： | 1 |
| 11 | Decomposition and ignition of the high-nitrogen compound triamino-guanidinium azotetrazolate(TAGZT)显示文摘 | Bryce C T Arif N A Steven F S et al | 2006 | Propellants Explosives Pyrotechnics2006，31，3： | 1 |
| 12 | Discrete Supramolecular Architecture vs Crystal Engineering:The Rational Design of a Platinum-Based Bimetallic Assembly with a Chairlike Structure and Its Infinite, Copper Analogue 显示文摘 | TABELLION F SEIDEL SR ARIF AM | 2001 | J Am Chem Soc2001，123，31： | 1 |
| 13 | The effect of sliding bubbles on nucleate boiling of a subcooled liquid flowing in a narrow channel显示文摘 | Arif B Ozer Ahmet F Oncel D Keith Hollingsworth | 2011 | International Journal of Heat and Mass Transfer2011，，54： | 1 |
| 14 | Roll deformation and stress distribution under thermo-mechanlcal loading in cold rolling显示文摘 | Arif A F M Khan O Sheikh A K | 2004 | Journal of Materials Processing Technology2004，147，： | 1 |
| 15 | Roll Deformation and Stress Distribution under Thermo-mechanical Loading in Cold Rolling显示文摘 | Arif A F M Khan O Sheikh A K | 2004 | Journal of Materials Processing Technology2004，147，2： | 1 |
| 16 | Roll deformation and stress distribution under thermo-mechanical loading in cold rolling显示文摘 | Arif A F M Ovaisullah Khan Sheikh A K | 2004 | Journal of Materials Processing Technology2004，147，： | 1 |
| 17 | Distinct gene arrangement in the Buzura suppressaria single-nucleocapsid nucleopolyhedrovirus genome显示文摘 | Arif B M F Jin | 1998 | Journal of Gen Virol1998，79，： | 1 |
| 18 | Numerical prediction of plastic deformation and residual stresses induced by laser shock processing显示文摘 | ARIF A F M | 2003 | Materials Processing Technology2003，136，： | 1 |
| 19 | Experimental and theoretical approach to evaluation of nanostructured carbon particles derived from phenolic resin via spray pyrolysis显示文摘 | Arif A F Balgis R Ogi T | 2015 | Chemical Engineering Journal2015，271，： | 1 |
| 20 | Agricultural Factors Affecting Methane Oxidation in Arable Soil 显示文摘 | ARIF M A S HOUWEN F VEIRSTRAETE W | 1996 | Biology and Fertility of Soils1996，21，12： | 1 |
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