|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype:Results of a 25-year follow-up study显示文摘IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.METHODS: Eight hundred and seventy-three IBD patients were enrolled (ulcerative colitis/UC/: 619, m/f: 317/302,mean age at presentation: 38.3 years, average disease duration: 11.2 years; Crohn's disease/CD/: 254, m/f: 125/129,mean age at presentation: 32.5 years, average disease duration: 9.2 years). Intestinal, extraintestinal signs and laboratory tests were monitored regularly. Any alteration suggesting an EIMs was investigated by a specialist.RESULTS: A total of 21.3% of patients with IBD had EIM (UC: 15.0%, CD: 36.6%). Age at presentation did not affect the likelihood of EIM. Prevalence of EIMs was higher in women and in CD, ocular complications and primary sclerosing cholangitis (PSC) were more frequent in UC. In UC there was an increased tendency of EIM in patients with a more extensive disease.Joint complications were more frequent in CD (22.4% VS UC 10.2%, P<0.01). In UC positive family history increased the risk of joint complications (OR:3.63). In CD the frequency of type-1 peripheral arthritis was increased in patients with penetrating disease (P=0.028). PSC was present in 1.6% in UC and 0.8% in CD. Dermatological complications were present in 3.8% in UC and 10.2% in CD, the rate of ocular complications was around 3% in both diseases. Rare complications were glomerulonephritis, autoimmune hemolytic anaemia and celiac disease.CONCLUSION: Prevalence of EIM in Hungarian IBD patients is in concordance with data from Western countries. The high number of EIM supports a role for complex follow-up in these patients.ACKNOWLEDGEMENTDr. Zsuzsanna Erdelyi, Dr. Agnes Horvath, Dr Gabor Mester (Veszprem), Dr. Sandor Meszaros (Ajka), Dr. Csaba Molnar help in data collection and to Gabriella Demenyi for technical assistance. | Laszlo Lakatos Tunde Pandur Gyula David Zsuzsanna Balogh Pal Kuronya Arpad Tollas Peter Laszlo Lakatos | 2003 | World Journal of Gastroenterology2003，9，10： | 25 |
| 2 | Striking elevation in incidence and prevalence of inflammatory bowel disease in a province of western Hungary between 1977-2001显示文摘AIM:An investigation into inflammatory bowel disease and colorectal cancer in Veszprem Province was conducted from 1977 to 2001.METHODS: Both hospital and outpatient records were collected and reviewed comprehensively. The majority of patients were followed up regularly.RESULTS:The population of the province was decreased from 386000 to 376000 during the period. Five hundred sixty new cases of ulcerative colitis (UC), 212 of Crohn's disease (CD), and 40 of indeterminate colitis (IC) were diagnosed. The incidence rates increased from 1.66 to 11.01 cases per 100 000 persons for UC, from 0.41 to 4.68 for CD and from 0.26 to 0.74 for IC. The prevalence rate at the end of 2001 was 142.6 for UC and 52.9 cases per 100 000 persons for CD. The peak onset age in UC patients was between 30 and 40 years, in CD between 20 and 30 years. A family history of IBD was present in 3.4% in UC and 9.9% in CD patients.Smoking increased the risk for CD (OR=1.94) while it decreased the risk for UC (OR=0.25). Twelve colorectal carcinomas were observed in this cohort, the cumulative colorectal cancer risk after 10 years in UC was 2%, after 20 years 8.8%, after 30 years 13.3%.CONCLUSION:The incidence and prevalence rates of IBD have increased steadily in Veszprem Province, now equivalent to that in Western European countries. Rapid increase in incidence rates supports a probable role for environmental factors. The rate of colorectal cancers in IBD is similar to that observed in Western countries. | Laszlo Lakatos Gabor Mester Zsuzsanna Erdelyi Mihaly Balogh Istvan Szipocs Gyorgy Kamaras Peter Laszlo Lakatos | 2004 | World Journal of Gastroenterology2004，10，3： | 17 |
| 3 | 近地磁尾重联中哨声波和Hall磁场的Cluster观测显示文摘在2001~2003年Cluster飞船通过近地磁尾期间,共探测到14次重联事件,在这些事件中同时还观测到等离子体波活动.本文把14次事件分为三大类,其中:第1类包含了8次事件,它们是在等离子体片内先于重联事件观测到波活动,并且还同时观测到Hall磁场.经过分析判断,这类事件中观测到的波是右旋偏振的哨声波.第Ⅱ类包含了2次事件,这类事件也观测到了Hall磁场和右旋偏振的哨声波.第Ⅲ类也包含了2次事件,这类事件只是普通的重联事件,没有观测到Hall磁场,但是波活动明显先于重联事件.在我们观测的14次事件中,比较强烈的哨声波和Hall磁场是一一对应的,因此哨声波可能主要是在Hall磁场的四极结构区激发的. | 魏新华 周国成 曹晋滨 O.Santolik H.Reme N.Cornilleau Andre Balogh | 2007 | 地球物理学报2007，50，3： | 5 |
| 4 | Is early limited surgery associated with a more benign disease course in Crohn's disease?显示文摘AIM:To analyze the difference in disease course and need for surgery in patients with Crohn’s disease(CD).METHODS:Data of 506 patients with incident CD were analyzed(age at diagnosis:31.5±13.8 years).Both hospital and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which includes incident CD patients diagnosed between January 1,1977 and December 31,2008.Follow-up data were collected until December 31,2009.All patients included had at least 1year of follow-up available.Patients with indeterminate colitis at diagnosis were excluded from the analysis.RESULTS:Overall,73 patients(14.4%)required resective surgery within 1 year of diagnosis.Steroid exposure and need for biological therapy were lower in patients with early limited surgery(P<0.001 and P=0.09).In addition,surgery rates during follow-up in patients with and without early surgery differed significantly after matching on propensity scores(P<0.001,HR=0.23).The need for reoperation was also lower in patients with early limited resective surgery(P=0.038,HR=0.42)in a Kaplan-Meier and multivariate Cox regression(P=0.04)analysis.However,this advantage was not observed after matching on propensity scores(PLogrank=0.656,PBreslow=0.498).CONCLUSION:Long-term surgery rates and overall exposure to steroids and biological agents were lower in patients with early limited resective surgery,but reoperation rates did not differ. | Petra Anna Golovics Laszlo Lakatos Attila Nagy Tunde Pandur Istvan Szita Mihaly Balogh Csaba Molnar Erzsebet Komaromi Barbara Dorottya Lovasz Michael Mandel Gabor Veres Lajos S Kiss Zsuzsanna Vegh Peter Laszlo Lakatos | 2013 | World Journal of Gastroenterology2013，19，43： | 3 |
| 5 | Statistical survey on the magnetic field in magnetotail current sheets: Cluster observations显示文摘The distribution properties of the magnetic field in magnetotail current sheets have been explored statistically with the magnetic measurement data of the Cluster mission from June to November of the years 2001–2005.It is found that,on average,the strength of the magnetic field and its Bz component in the current sheet are weaker in the region close to midnight but stronger near the dawnside and duskside flanks,which implies that,in general,a thinner current sheet occurs near midnight and thicker ones near both flanks.The occurrence of tail current sheet flapping is higher on both flanks than in the midnight region,although it is most frequent in the dawn flank.Current sheets with a negative Bz component or a strong By component have a higher probability of occurring at magnetic local times of 21:00–01:00,indicating that magnetic activity,e.g.magnetic reconnection and current disruption occur more frequently there.Statistically,the probability distributions of the By component and the tilt angle of magnetic field lines in the current sheet are approximately normal distributions,and the occurrence probability of the flattened current sheet is about one third that of the normal current sheet.The magnetic field and Bz component in the current sheet mainly vary from 1 nT to 10 nT.The By component in the tail central current sheet is on average twice the IMF By at 1 AU. | RONG ZhaoJin SHEN Chao LUCEK E BALOGH A YAO Li | 2010 | Chinese Science Bulletin2010，55，23： | 3 |
| 6 | Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort显示文摘AIM:To investigate the evolution of disease phenotypein adult and pediatric onset Crohn's disease(CD) populations,diagnosed between 1977 and 2008.METHODS:Data of 506 incident CD patients were analyzed(age at diagnosis:28.5 years,interquartile range:22-38 years).Both in-and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which included incident patients diagnosed between January 1,1977 and December 31,2008 in adult and pediatric onset CD populations.Disease phenotype according to the Montreal classification and long-term disease course was analysed according to the age at onset in time-dependent univariate and multivariate analysis.RESULTS:Among this population-based cohort,seventy-four(12.8%) pediatric-onset CD patients were identified(diagnosed ≤ 17 years of age).There was no significant difference in the distribution of disease behavior between pediatric(B1:62%,B2:15%,B3:23%) and adult-onset CD patients(B1:56%,B2:21%,B3:23%) at diagnosis,or during follow-up.Overall,the probability of developing complicated disease behaviour was 49.7% and 61.3% in the pediatric and 55.1% and 62.4% in the adult onset patients after 5-and 10-years of follow-up.Similarly,time to change in disease behaviour from non stricturing,non penetrating(B1) to complicated,stricturing or penetrating(B2/B3) disease was not significantly different between pediatric and adult onset CD in a Kaplan-Meier analysis.Calendar year of diagnosis(P = 0.04),ileal location(P < 0.001),perianal disease(P < 0.001),smoking(P = 0.038) and need for steroids(P < 0.001) were associated with presence of,or progression to,complicated disease behavior at diagnosis and during follow-up.A change in disease location was observed in 8.9% of patients and it was associated with smoking status(P = 0.01),but not with age at diagnosis.CONCLUSION:Long-term evolution of disease behavior was not different in pediatric-and adult-onset CD patients in this population-based cohort but was associated to location,perianal disease and smoking status. | Barbara Dorottya Lovasz Laszlo Lakatos Agnes Horvath Istvan Szita Tunde Pandur Michael Mandel Zsuzsanna Vegh Petra Anna Golovics Gabor Mester Mihaly Balogh Csaba Molnar Erzsebet Komaromi Lajos Sandor Kiss Peter Laszlo Lakatos | 2013 | World Journal of Gastroenterology2013，19，14： | 2 |
| 7 | 3H Dendrimer Nanoparticle Organ/Tumor Distribution显示文摘 | Shraddha S. Nigavekar Lok Yun Sung Mikel Llanes Areej El-Jawahri Theodore S. Lawrence Christopher W. Becker Lajos Balogh Mohamed K. Khan | 2004 | Pharmaceutical Research2004，，3： | 2 |
| 8 | Solar wind entry via flux tube into magnetosphere observed by Cluster measurements at dayside magnetopause during southward IMF显示文摘By analyzing hot ion and electron parameters together with magnetic field measurements from Cluster, an event of magnetopause crossing of the spacecraft has been investigated. At the latitude of about 40° and magnetic local time (MLT) of 13:20 during the southward interplanetary magnetic field (IMF), a transition layer was observed, with the magnetospheric field configuration and cold dense plasma features of the magnetosheath. The particle energy-time spectrograms inside the layer were similar to but still a little different from those in the magnetosheath, obviously indicating the solar wind entry into the magnetosphere. The direction and magnitude of the accelerated ion flow implied that reconnection might possibly cause such a solar wind entry phenomenon. The bipolar signature of the normal magnetic component BN in magnetopause coordinates further supported happening of reconnection there. The solar wind plasma flowed toward the magnetopause and entered the magnetosphere along the reconnected flux tube. The magnetospheric branch of the reconnected flux tube was still inside the magnetosphere after reconnection and supplied the path for the solar wind entry into the dayside magnetosphere. The case analysis gives observational evidence and more details of how the reconnection process at the dayside low latitude magnetopause caused the solar wind entry into the magnetosphere. | M. Dunlop A. Balogh H. Rème Y. V. Bogdanova A. Fazakerley | 2009 | Science China(Technological Sciences)2009，52，7： | 2 |
| 9 | Special nanostructures in Al-Mg alloys subjected to high pressure torsion显示文摘Deformation twins and stacking faults were observed in nanostructure Al-Mg alloys subjected to high pressure torsion.These observations are surprising because deformation twinnings have never been observed in their coarse-grained counterparts under normal conditions.Experimental evidences are introduced on non-equilibrium grain boundaries,deformation twinnings and partial dislocation emissions from grain boundaries.Some of these features can be explained by the results reported from molecular-dynamics simulations of pure FCC metals.Special emphasis is laid on the recent observations of high density hexagonal and rhombic shaped nanostructures with an average size of 3 nm in the Al-Mg alloys processed by high pressure torsion.A possible formation process of these nanostructures is proposed based on molecular-dynamics simulations. | 刘满平 Hans J.ROVEN 刘新涛 Maxim MURASHKIN Ruslan Z.VALIEV Tamas UNGáR Levente BALOGH | 2010 | Transactions of Nonferrous Metals Society of China2010，20，11： | 2 |
| 10 | Analysis of the Interaction between Low-Frequency Waves and Ions in the High-Altitude Cusp Region Observed by Satellite Cluster显示文摘在离子(质子) 和在从 0.3 ~ 10 Hz 的频率范围 f (1 ) 的低频率波浪(LFW ) 之间的精力转移被穿过高高度的极的尖顶的簇观察。在低频率波浪和离子之间的精力转移有二个工具。一个人是精力从低频率被转移向离子和离子精力增加招手。其它是精力从离子被转移到低频率波浪和离子精力减少。离子旋转运动在精力转移过程起一个重要作用。LFW 能加速或速度的 f (1 ) 的电磁的地沿着周围的磁场的方向的质子并且温暖或使冷在周围的磁场的平行、垂直的方向的质子。质子数字密度的山峰价值有电磁的精力 oflow 频率波浪的相应山峰价值。这暗示运动 Alfven 波浪和独居的运动 Alfven 波浪可能在高高度的尖顶区域存在。 | 段素平 刘振兴 曹晋滨 史建魁 路立 李中元 Q. G. Zong H. Reme N. Cornilleau-Wehrlin A. Balogh M. Andre | 2006 | Chinese Physics Letters2006，23，5： | 2 |
| 11 | Analysis of optic disc damage by optical coherence tomography in terms of therapy in non-arteritic anterior ischemic optic neuropathy显示文摘This study aimed to assess the relationship between the rate of nerve fiber loss in non-arteritic anterior ischemic optic neuropathy(NAION) and time delay before therapy.Total 24 patients received the same treatment within or after 2wk(early and late groups).There were significantly lower level of destruction of nerve fibers(P=0.0014) and significantly better visual field sensitivity(P=0.039) in early group.The results indicate that therapy should be started within 2wk.The degree of ischemic damage due to NAION correlates well with retinal nerve fiber layer thickness and the ischemia-induced decrease in visual field sensitivity. | Zsuzsa Balogh Marta Kasza Julianna Varadai Izabella Reznek Judit Damjanovich Adrienne Csutak Andras Berta Valeria Nagy | 2016 | International Journal of Ophthalmology(English edition)2016，9，9： | 2 |
| 12 | Bacteriophages for plant disease control 显示文摘 | Jones J B Jackson L E Balogh B Obradovic A Iriarte F B Momol M T | 2007 | Annu Rev Phytopathol2007，45，： | 1 |
| 13 | Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma显示文摘 | Suliburk JW Ware DN Balogh Z | 2003 | J Trauma2003，55，6： | 1 |
| 14 | Transport of mercury in three contrasting river basins显示文摘 | Balogh S J Meyer M L Johnson D K | 1998 | Environ Sci Technol1998，32，： | 1 |
| 15 | Evidence for the notch signaling pathway on the role of estrogen in an giogenesis显示文摘 | Soares R Balogh G Guo S | 2004 | Mol Endocrinol2004，18，9： | 1 |
| 16 | Poly(Amidoamine) dendrimer-templated nanocomposites: 1, Synthesis of zerovalent copper nanoclusters显示文摘 | Balogh L Tomalia D A | 1998 | J Am Chem Soc1998，120，： | 1 |
| 17 | Angle of arrival estimation based on interferometer principle 显示文摘 | Balogh L Kollar I | 2003 | IEEE International Symposium on Intelligent Signal Processing2003，31，4： | 1 |
| 18 | Poly(amidoamine) dendrimer-templated nanoc omposites Synthesis of zerovalent copper nanocluster显示文摘 | Balogh L Tomalia DA | 1998 | J Am Chem Soc1998，120，： | 1 |
| 19 | A dispersive liquid-liquid microextraction procedure for UV-Vis spectrophotometric determination of chromium(vi) in water samples显示文摘 | ALEXOVIG M BALOGH I S SKRLIKOVA J | 2012 | Analytical Methods2012，4，5： | 1 |
| 20 | Interleukin-33 – cytokine of dual function or novel alarmin?显示文摘 | Guttorm Haraldsen Johanna Balogh Jürgen Pollheimer Jon Sponheim Axel M. Küchler | 2009 | Trends in Immunology2009，，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员