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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 3 | Pericytes synthesize renin显示文摘AIM: To investigate renin expression in pericytes during normal kidney development and after deletion of angiotensinogen, the precursor for all angiotensins.METHODS: We examined the distribution of renin expressing cells by immunoshistochemistry in the interstitial compartment of wild type(WT) and angiotensinogen deficient(AGT-/-) mice at different developmental stages from embryonic day 18(E18: WT, n = 4; AGT-/-, n = 5) and at day 1(P1: WT, n = 5; AGT-/-, n = 5), 5(P5: WT, n = 7; AGT-/-, n = 8), 10(P10: WT, n = 3; AGT-/-, n = 5), 21(P21: WT, n = 7; AGT-/-, n = 5), 45(P45: WT, n = 3; AGT-/-, n = 3), and 70(P70: WT, n = 2; AGT-/-, n = 2) of postnatal life. We quantified the number of pericytes positive for renin at all the developmental stages mentioned above and comparedthe results of AGT-/- mice to their WT counterparts.RESULTS: In WT mice, renal interstitial pericytes synthesize renin in early life supporting a lineage relationship with renin cells in the vasculature. The number of pericytes positive for renin per area of 0.32 mm2(density) in WT mice was maintained from fetal life till weaning age(E18 = 4.25 ± 0.63, P1 = 3.75 ± 0.48, P5 = 3.75 ± 0.48, P10 = 4 ± 0.71, P21 = 3.8 ± 0.58) and markedly decreased in adult life(P45 = 1.2 ± 0.37, P70 = 0.8 ± 0.20). On the other hand, in AGT-/- mice the density of pericytes expressing renin was not significantly different from WT mice at E18 and P1: E18 = 5.75 ± 0.50 vs 4.25 ± 0.63(P = 0.106), P1 = 9.25 ± 3.50 vs 3.75 ± 0.48(P = 0.175) but significantly increased from P5 till P70: P5 = 38.25 ± 5 vs 3.75 ± 0.48(P = 0.0004), P10 = 173 ± 7.50 vs 4 ± 0.70(P = 5.24567 × 10-7), P21 = 83 ± 6.70 vs 3.8 ± 0.58(P = 2.97358 × 10-6), P45 = 49 ± 3.50 vs 1.2 ± 0.37(P = 8.18274 x 10-7) and P70 = 17.8 ± 2.30 vs 0.8 ± 0.20(P = 3.51151 × 10-5). The AGT-/- mice showed a marked increase in the number of pericytes per field studied starting from P5, reaching its peak at P10, and then a gradually decreasing until P70. CONCLUSION: Interstitial pericytes synthesize renin during development and the number of renin-expressing pericytes increases in response to a homeostatic threat imposed early in life such as lack of angiotensinogen. | Alison C Berg Catalina Chernavvsky-Sequeira Jennifer Lindsey R Ariel Gomez Maria Luisa S Sequeira-Lopez | 2013 | World Journal of Nephrology2013，2，1： | 2 |
| 4 | Focused crawling: a new approach to topic-specific Web resource discovery显示文摘 | CHARKRABARTI S BERG M van den DOM B | 1999 | Computer Networks1999，31，1116： | 1 |
| 5 | Serial analysis of gene expression:rapid RT-PCR analysis of unknown SAGE tags显示文摘 | Leij J Poppema S | 1999 | Nucleic Acids Res1999，27，： | 1 |
| 6 | Tow-year remission and subsequent relapse in children with newly diagnosed epilepsy显示文摘 | Berg AT Shinnar S Lery SR | 2002 | Epilepsy2002，42，12： | 1 |
| 7 | Tumor - infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T - cell response against tumor - associated antigens and survival显示文摘 | NAGORSEN D VOIGT S BERG E | 2007 | J Transl Med2007，5，29： | 1 |
| 8 | Breakup and Fusion of Self- Guide Femtosecond Light Pulses in Air 显示文摘 | TZORTZAKIS S BERGE L | 2002 | Physical Review Letters2002，，86： | 1 |
| 9 | Albumin extravasation and tissue washout of hyaluronan after plasma volume expansion with crystalloid or hypooncotic colloid solutions显示文摘 | Berg S Golster M Lisander B | 2002 | Acta Anaesthesiol Scand2002，46，2： | 1 |
| 10 | Predictors of outcome in Henoch-Sch (o)nlein nephritis显示文摘 | Edstrom Halling S Soderberg MP Berg UB | 2010 | Pediatric Nephrolo2010，25，6： | 1 |
| 11 | Dose reduction in dynamic perfusion CT of the brain:Effects of the scan frequency on measurements of cerebral blood flow,cerebral blood volume,and mean transit time显示文摘 | WIESMANN M BERG S BOHNER G | 2008 | Eur Radiol2008，18，12： | 1 |
| 12 | DOING THERAPY: A POST-STRUCTURAL RE-VlSION显示文摘 | Shazer S Berg I K | 1992 | Journal of Marital and Family Therapy1992，18，1： | 1 |
| 13 | The risk of seizure recurrence after a first unprovoked afebrile seizure in childhood: an extended follow-up 显示文摘 | Shinnar S Berg AT Mosbe SL e~ al | 1996 | Pediatrics1996，98，21： | 1 |
| 14 | Doing therapy: A post-structural revision显示文摘 | De SHAZER S BERG I K | 1992 | J Marital Family Therapy1992，18，： | 1 |
| 15 | Expression of estrogen receptors alpha and beta in human lung tissue and cell lines显示文摘 | Mollerup S Jrgensen K Berge G Haugen A | 2002 | Lung Cancer2002，37，2： | 1 |
| 16 | Regu-lation of colon carcinoma cell invasion by hypoxia-induc-ible factor 1显示文摘 | Krishnamachary B Berg Dixon S Kelly B | 2003 | Cancer Res2003，63，5： | 1 |
| 17 | Regulation of hypoxia-inducible factor 1 in enterocytic cells显示文摘 | Bertges DJ Berg S Fink MP Delude RL | 2002 | J Surg Res2002，106，1： | 1 |
| 18 | Parameter dependence of homoclinic solutions in a single long Josephson junction显示文摘 | BERG J B GILS S A VISSER T P | 2003 | Nonlinearity2003，16，： | 1 |
| 19 | Change in depression as aprecursor of cardiovascular events: SHEP Cooperative Research Group (systolic hypertensionin the elderly)显示文摘 | 2,Wasserthiel-Smoller S Applegate WB Berge K | 1996 | Arch Intern Med1996，156，5： | 1 |
| 20 | Early development of intractable epilepsy in children:a prospective study显示文摘 | Berg AT Shinnar S Levy SR | 2001 | Neurology2001，56，： | 1 |
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