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| 1 | Patterns of local recurrence in rectal cancer after a multidisciplinary approach显示文摘Improvements in surgery and the application of combined approaches to fight rectal cancer have succeeded in reducing the local recurrence (LR) rate and when there is LR it tends to appear later and less often in isolation. Moreover, a subtle change in the distribution of LRs with respect to the pelvis has been observed. In general terms, prior to total mesorectal excision the most common LRs were central types (perianastomotic and anterior) while lateral and posterior forms (presa-cral) have become more common since the growth in the use of combined treatments. No differences have been reported in the current pattern of LRs as a function of the type of approach used, that is, neo-adjuvant therapies (short-term or long-course radiotherapy, orchemoradiotherapy versus extended lymphadenectomy, though there is a trend towards posterior or presacral LR in patients in the Western world and lateral LR in Asia. Nevertheless, both may arise from the same mechanism. Moreover, as well as the mode of treatment, the type of LR is related to the height of the initial tumor. Nowadays most LRs are related to the advanced nature of the disease. Involvement of the circumferential radial margin and spillage of residual tumor cells from lymphatic leakage in the pelvic side wall are two plausible mechanisms for the genesis of LR. The patterns of pelvic recurrence itself (pelvic subsites) also have important implications for prognosis and are related to the potential success of salvage curative approach. The re-operability for cure and prognosis are generally better for anastomotic and anterior types than for presacral and lateral recurrences. Overall survival after LR diagnosis is lower with radio or chemoradiotherapy plus optimal surgery approaches, compared to optimal surgery alone. | Jose M Enríquez-Navascués Nerea Borda Aintzane Liz-erazu Carlos Placer Jose L Elosegui Juan P Ciria Adelaida Lacasta Luis Bujanda | 2011 | World Journal of Gastroenterology2011，17，13： | 14 |
| 2 | Wireless capsule endoscopy显示文摘Wireless capsule endoscopy is a new technique that allows complete exploration of the small bowel without external wires. Its role has been analyzed in many small bowel diseases such as obscure gastrointestinal bleeding, Crohn's disease and gastrointestinal polyposis syndromes with promising results. Studies on other pathologies (i.e. small bowel tumour, celiac disease) are under evaluation to define the role of this technique. | A Mata J Llach JM Bordas | 2008 | World Journal of Gastroenterology2008，14，13： | 12 |
| 3 | Colon capsule endoscopy显示文摘Wireless capsule endoscopy has become the first imaging tool for small bowel examination. Recently, new capsule endoscopy applications have been developed, such as esophageal capsule endoscopy and colon capsule endoscopy. Clinical trials results have shown that colon capsule endoscopy is feasible, accurate and safe in patients suffering from colonic diseases. It could be a good alternative in patients refusing conventional colonoscopy or when it is contraindicated. Upcoming studies are needed to demonstrate its utility for colon cancer screening and other indications such us ulcerative colitis. Comparative studies including both conventional and virtual colonoscopy are also required. | Ignacio Fernandez-Urien Cristina Carretero Ana Borda Miguel Muoz-Navas | 2008 | World Journal of Gastroenterology2008，14，34： | 4 |
| 4 | Prognosis and follow-up of 135 patients with ischemic colitis over a five-year period显示文摘AIM:To study the prognosis(recurrence and mortality)of patients with ischemic colitis(IC).METHODS:This study was conducted in four Spanish hospitals,participants in the Ischemic Colitis in Spain study We analyzed prospectively 135 consecutive patients who met criteria for definitive or probable IC according to Brandt criteria,and follow up these patients during the next five years,retrospectively.Long-term results(recurrence and mortality)were evaluated retrospectively after a median interval of 62 mo(range54-75 mo).RESULTS:Estimated IC recurrence rates were 2.9%,5.1%,8.1%and 9.7%at years 1,2,3 and 5 years,respectively.Five-year survival was 69%(93 of 135)and 24%(10 of 42 patients)died for causes related to the IC.Among these 10 patients,8 died in their first episode at hospital(4 had gangrenous colitis and 4 fulminant colitis)and 2 due to recurrence.CONCLUSION:The five-year recurrence rate of IC was low.On the other hand,mortality during follow-up was high and was not associated with ischemic colitis. | Angel Cosme Miguel Montoro Santos Santolaria Ana B Sanchez-Puertolas Marta Ponce Margarita Durán Jose Luis Cabriada Nerea Borda Cristina Sarasqueta Luis Bujanda | 2013 | World Journal of Gastroenterology2013，19，44： | 2 |
| 5 | Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2frames-per-second?显示文摘AIM: To compare the current capsule and a new prototype at 2 and 4 frames-per-second, respectively, in terms of clinical and therapeutic impact. METHODS: One hundred patients with an indication for capsule endoscopy were included in the study. All procedures were performed with the new device(SB24). After an exhaustive evaluation of the SB24 videos, they were then converted to 'SB2-like' videos for their evaluation. Findings, frames per finding, and clinical and therapeutic impact derived from video visualization were analyzed. Kappa index for interobserver agreement and χ2 and Student's t tests for qualitative/quantitative variables, respectively, were used. Values of P under 0.05 were considered statistically significant.RESULTS: Eighty-nine out of 100 cases included in the study were ultimately included in the analysis. The SB24 videos detected the anatomical landmarks(Zline and duodenal papilla) and lesions in more patients than the 'SB2-like' videos. On the other hand, the SB24 videos detected more frames per landmark/lesion than the 'SB2-like' videos. However, these differences were not statistically significant(P > 0.05). Both clinical and therapeutic impacts were similar between SB24 and 'SB2-like' videos(K = 0.954). The time spent by readers was significantly higher for SB24 videos visualization(P < 0.05) than for 'SB2-like' videos when all images captured by the capsule were considered. However, these differences become non-significant if we only take into account small bowel images(P > 0.05).CONCLUSION: More frames-per-second detect more landmarks, lesions, and frames per landmark/lesion, but is time consuming and has a very low impact on clinical and therapeutic management. | Ignacio Fernandez-Urien Cristina Carretero Erika Borobio Ana Borda Emilio Estevez Sara Galter Begoa Gonzalez-Suarez Benito Gonzalez Marisol Lujan Jose Luis Martinez Vanessa Martínez Pedro Menchén Javier Navajas Vicente Pons Cesar Prieto Julio Valle | 2014 | World Journal of Gastroenterology2014，20，39： | 2 |
| 6 | Application of Cloud Computing in the Public Sector in Hungary显示文摘 | Maria Bordas | 2012 | Journal of US-China Public Administration2012，9，5： | 2 |
| 7 | The role of ultrasonography and automatic-needle biopsy in outpatient percutaneous liver biopsy显示文摘 | KD Lindor C Bru RA Jorgensen J Rakela JM Bordas JB Gross J Rodes DB McGill CC Reading EM James JW Charboneau J Ludwig KP Batts AR Zinsmeister | 1996 | Hepatology1996，，5： | 2 |
| 8 | Optimum conditions for the synthesis of linear polylactie acid - based urethanes 显示文摘 | Borda J Bodnar I Keki S | 2000 | J Polym Sci Part A : Polym Chem2000，38，6： | 1 |
| 9 | Effects of isosorbide-5-mononitrate on vertical pressure and systemic haemodynamics in patients with cirrhosis显示文摘 | Albillos A Feu F Bordas JM | 1996 | J hepatol1996，24，： | 1 |
| 10 | Effect of bolus injection and continuous infusion of somatostafin on gastric perfusion in cirrhotic patients with portal - hypertensive gastropathy显示文摘 | Panes J Pique JM Bordas JM | 1994 | Hepatology1994，20，： | 1 |
| 11 | An essential role for phoP in Mycobacterium tuberculosis virulence显示文摘 | Perez E Samper S Bordas Y | 2001 | Mol Microbiol2001，41，： | 1 |
| 12 | Adsorption of copper, cadmium, lead and zinc onto a synthetic manganese oxide显示文摘 | PUPPA L D KOM~REK M BORDAS F | 2013 | Journal of Colloid and Interface Science2013，，399： | 1 |
| 13 | Sphincterotomy in the treatment of biliary leakage显示文摘 | Bordas JM Elizalde JI | 2002 | Hepatogastroenterology2002，49，： | 1 |
| 14 | Effect of polyphenols from the Mediterranean diet on proliferation and mediators of in vitro invasiveness of the MB-49 routine bladder cancer cell line 显示文摘 | Garcia Mediero JM Ferruelo Alonso A Paez Borda A | 2005 | Actas Urol Esp2005，29，8： | 1 |
| 15 | Extraction of extracellular polymeric substances (EPS) from anaerobic granular sludge:comparison of chemical and physical extraction protocols 显示文摘 | D' abzac P Bordas F Van Hullebusch E | 2010 | Applied Microbiology and Biotechnology2010，85，5： | 1 |
| 16 | Formation and stability of heterocyclic amines in a meat flavour model system: effects of temperature, time and precursors 显示文摘 | Bordas M Moyano E Ptfignou L | 2004 | Journal of Chromatography B2004，802，： | 1 |
| 17 | Wireless capsule endoscopy in patiems with obscure gastrointestinal bleeding: a comparative study with push enteroscopy 显示文摘 | Mata A Bordas JM Feu F | 2004 | Aliment Pharmacol Ther2004，20，： | 1 |
| 18 | A balanced nucleotide supply makes sense显示文摘 | Borda E Martinez Puig D Cordoba X | 2003 | Feed Mix2003，，11： | 1 |
| 19 | Papular elastorrhexis: a variety of nevus anelasticus?显示文摘 | Bordas X Ferrandiz C Ribera M | 1987 | Arch Dermatol1987，123，4： | 1 |
| 20 | Anti- M3 peptide IgG from Sjogren's syndrome triggers apoptosis in A253 cells 显示文摘 | Rejna S Sterin- Borda L Borda E | 2012 | Cell Immu- nol2012，275，12： | 1 |
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