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| 1 | 健康成人动脉粥样硬化斑块易感性和血栓形成的生物标志物变化与极端空气污染水平相关:北京AIRCHD研究显示文摘空气污染与心血管事件恶化的病理生理机制尚不完全清楚。该文探讨环境空气污染是否可以触发易损斑块.通过全身炎症途径促进血栓形成。方法:在北京AIRCHD研究中.2014-2016年间对73名健康成年人[年龄(23.3±5.4)岁]进行了随访。研究者使用线性混合效应模型评估了空气污染物与动脉粥样硬化斑块易损性、血栓形成和炎症相关生物标志物之间的关系,并使用中介效应分析(mediation analyses)探讨涉及的生物学途径。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析评估每种生物标记物预测环境空气污染暴露的能力。 | 刘青 叶鹏 Xu H Wang T Liu S Brook RD Feng B Zhao Q Song X Yi T Chen J Zhang Y Wang Y Zheng L Rajagopalan S Li J Huang W | 2019 | 中华高血压杂志2019，27，4： | 13 |
| 2 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008，，5： | 8 |
| 3 | Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3显示文摘 | Brooks P C Stromblad S Sanders L C | 1996 | Cell1996，85，5： | 4 |
| 4 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015，5，4： | 3 |
| 5 | Benefits of the use of blood conservation in scoliosis surgery显示文摘AIM To investigate whether autologous blood transfusion(ABT) drains and intra-operative cell salvage reduced donor blood transfusion requirements during scoliosis surgery.METHODS Retrospective data collection on transfusion requirements of patients undergoing scoliosis surgery is between January 2006 and March 2010. There were three distinct phases of transfusion practice over this time: Group A received 'traditional treatment' with allogeneic red cell transfusion(ARCT) in response to an intra- or postoperative anaemia(Hb < 8 g/d L or a symptomatic anaemia); Group B received intra-operative cell salvage in addition to 'traditional treatment'. In group C,ABT wound drains were used together with both intra-operative cell salvage and 'traditional treatment'.RESULTS Data from 97 procedures on 77 patients,there was no difference in mean preoperative haemoglobin levels between the groups(A: 13.1 g/d L; B: 13.49 g/d L; C: 13.66 g/d L). Allogeneic red cell transfusion was required for 22 of the 37 procedures(59%) in group A,17 of 30(57%) in group B and 16 of 30(53%) in group C. There was an overall 6% reduction in the proportion of patients requiring an ARCT between groups A and C but this was not statistically significant(χ2 = 0.398). Patientsin group C received fewer units(mean 2.19) than group B(mean 2.94)(P = 0.984) and significantly fewer than those in group A(mean 3.82)(P = 0.0322). Mean length of inpatient stay was lower in group C(8.65 d) than in groups B(12.83) or A(12.62).CONCLUSION When used alongside measures to minimise blood loss during surgery,ABT drains and intra-operative cell salvage leads to a reduced need for donor blood transfusion in patients undergoing scoliosis surgery. | Peter R Loughenbury Lyeanda Berry Ben T Brooke Abhay S Rao Robert A Dunsmuir Peter A Millner | 2016 | World Journal of Orthopedics2016，7，12： | 3 |
| 6 | A predictive tool to evaluate disc brake squeal propensity, Part 2: System linearization and modal analysis显示文摘 | LEE Y S BROOKS P C BARTON D C | 2003 | International Journal of Vehicle Design2003，31，： | 1 |
| 7 | National beef tenderness survey-1998显示文摘 | Brooks J C Gwartney J B Hale D S | 2000 | J Anim Sci2000，78，： | 1 |
| 8 | Thoughts beyond words:When language overshadows insight显示文摘 | Ohlsson S Brook K | 1993 | Journal of Experimental Psychology:General1993，，： | 1 |
| 9 | The taxonomic value of floral characters in tribe Trigonelleae (Leguminosae),with special reference to Medicago显示文摘 | Small E Crompton C W Brookes B S | 1981 | Canadian Journal of Botany1981，59，9： | 1 |
| 10 | Mutations in ABC1 in Tan- gier disease and familial high-density lipoprotein deficiency显示文摘 | Brooks WA Marcil M Clee S M | 1999 | Nat Genet1999，22，4： | 1 |
| 11 | The effect of osteogenic growth factors on bone growth into a ceramic-filled defect around an implant显示文摘 | Clarke S A Brooks R A Lee P T | 2004 | Bone Joint Surg Br2004，22，5： | 1 |
| 12 | Measurement of soil microbial biomass provides an early indication of chan- ges in total soil organic matter due to straw in corporation 显示文摘 | Powlson D S Brookes P C Christensen B | 1987 | Soil Biol Bioehem1987，19，： | 1 |
| 13 | Molecularcloning and expression of ovarian cathepsin D in seabream,Sparusauratal显示文摘 | CARNEVALI O CENTONZE F BROOKS S | 1999 | Biol Reprod1999，61，3： | 1 |
| 14 | Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer 显示文摘 | Urayama S Zou W Brooks K Tolstikov V | 2010 | Rapid Commun Mass Spectrom2010，24，： | 1 |
| 15 | Phosphorus in the soil mi- crobial biomass显示文摘 | Brooks P C Powlson D S Jenkinson D S | 1984 | Soil Biol Biochem1984，16，： | 1 |
| 16 | Nitric oxide partitioning into mitochondrial membranes and the control of respiration at cytochrome C oxidase显示文摘 | Shiva S Brookes PS Patel RP | 2001 | Proc Natl Acad Sci2001，98，13： | 1 |
| 17 | An extraction method for measuring soil microbial biomass C显示文摘 | Vance E D Brooks P C Jenkinson D S | 1987 | Soil Biology and Biochemistry1987，19，6： | 1 |
| 18 | An extraction method for measuring soil microbial biomass显示文摘 | Vance E D Brookes P C Jenkinson D S | 1987 | Soil Biology & Biochemistry1987，19，： | 1 |
| 19 | Measurement of microbial biomass phosphorus in soil 显示文摘 | BROOKES P C POWLSON D S JENKEINSON D S | 1982 | Soil Biology & Biochemistry1982，14，： | 1 |
| 20 | The action of chromium on serum lipids and on atherosclerosis in cholesterol feed rabbits 显示文摘 | Abraham A S Brooks B A Eylath U | 1982 | Atherosclersis1982，42，： | 1 |
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