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| 1 | Hyperferritinemia is a risk factor for steatosis in chronic liver disease显示文摘AIM: To investigate the relationship between ferritin and steatosis in patients with chronically abnormal liver function tests (LFTs) and high ferritin level. METHODS: One hundred and twenty-four consecutive patients with hyperferritinemia (male > 300 ng/mL, female > 200 ng/mL) were evaluated; clinical, biochemical and serological data, iron status parameters, HFE gene mutations and homeostasis model assessment score were obtained. Steatosis was graded by ultrasound as absent or present. Histology was available in 53 patients only. RESULTS: Mean level of ferritin was 881 ± 77 ng/mL in men and 549 ± 82 ng/mL in women. The diagnosis was chronic hepatitis C in 53 (42.7%), non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in 57 (45.9%), and cryptogenic liver damage in 14 (11.3%). None was diagnosed as hereditary hemochromatosis (HH). Hepatic siderosis on liver biopsy was present in 17 of 54 (32%) patients; grade 1 in eight and grade 2 in nine. Overall, 92 patients (74.2%) had steatosis. By logistic regression, ferritin and γ-glutamyltransferase were independent predictors of steatosis. Ferritin levels were signifi cantly related to low platelet count, steatosis and hepatitis C virus infection. CONCLUSION: In a non-obese cohort of non-alcoholic patients with chronically abnormal LFTs without HH, high serum ferritin level is a risk factor for steatosis. | Anna Licata Maria Elena Nebbia Giuseppe Cabibbo Giovanna Lo Iacono Francesco Barbaria Virna Brucato Nicola Alessi Salvatore Porrovecchio Vito Di Marco Antonio Craxì Calogero Cammà | 2009 | World Journal of Gastroenterology2009，15，17： | 6 |
| 2 | On the simulation of thermoplastic injection molding process:Ⅱ Relevance of interaction between flow and crystallization显示文摘 | Titomanlio G Sporanza V Brucato V | 1997 | International Polymer Processing1997，12，1： | 1 |
| 3 | Prognosis of idiopathic recurrent peri-carditis as determined from previously published reports显示文摘 | Imazio M Brucato A Adler Y Brambilla G Artom G Cecchi E | 2007 | Am J Cardiol2007，100，： | 1 |
| 4 | Controversial issues in the management of pericardial diseases显示文摘 | Imazio M Spodick DH Brucato A | 2010 | Circulation2010，121，7： | 1 |
| 5 | Aetiological diagnosis in acute and recurrent pericarditis:when and how显示文摘 | Imazio M Brucato A Derosa FG | 2009 | J Cardiovasc Med (Hagerstown)2009，10，3： | 1 |
| 6 | Numerical simulations of the dependency of flow pattern on impeller clearance in stirred vessels 显示文摘 | MONTANTE G LEE K C BRUCATO A | 2001 | Chemical Engineering Science2001，56，12： | 1 |
| 7 | A randomized trial of colchicine for acute pericarditis显示文摘 | Imazio M Brucato A Cemin R | 2013 | N Engl J Med2013，369，16： | 1 |
| 8 | Colchicine for recurrent pericarditis (CORP):a randomized trial显示文摘 | Imazio M Brucato A Cemin R | 2011 | Ann Intern Med2011，155，7： | 1 |
| 9 | Risk of congenitalcomplete heart block in newborns of mothers with anti-RO/SSA antibodies detected by counterimmunoelectro-phoresis:aprospective study of 100 women显示文摘 | Brucato A Frassi M Franceschini F | 2001 | ArthritisRheum2001，44，8： | 1 |
| 10 | State of the art: Reproduction and pregnancy in rheumatic diseases 显示文摘 | stensen M Andreoli L Brucato A | 2015 | Autoimmun Rev2015，14，5： | 1 |
| 11 | Efficacy and safety of colchicine for treatment of multiple recurrences of pericarditis (CORP-2):a multicentre,double-blind,placebo- controlled,randomised trial显示文摘 | Imazio M Belli R Brucato A | 2014 | Lancet2014，383，9936： | 1 |
| 12 | Extracellular poly(3-hydroxybutyrate) depolymerase of Penicillium funiculosum:general characteristics and active site studies显示文摘 | Brucato C L Wong S S | 1991 | Arch Bioehem Biophys1991，290，： | 1 |
| 13 | Clincal features and risk of congenital cardiac heart block in newborns from mothers with anti Ro/SSA antibodies clinical features and risk of congenital cardiac heart显示文摘 | Frassi M Brucato A Cavazzana I | 2001 | Reumatismo2001，53，4： | 1 |
| 14 | Concentration of autoantibodies to native 60-kd Ro/SS-A and denatured 52-kd RO/SS-A in eluates from the heart of a child who died with congenital complete heart block显示文摘 | Reichlin M Brucato A Frank MB | 1994 | Arthritis Rheum1994，37，： | 1 |
| 15 | Risk ofconstrictive pericarditis after acute pericarditis显示文摘 | Imazio M Brucato A Maestroni S | 2011 | Circulation2011，124，11： | 1 |
| 16 | Pericardial effusion triage 显示文摘 | Imazio M Mayosi BM Brucato A | 2010 | Journal of Cardiovascular Medicine2010，145，2： | 1 |
| 17 | Numerical prediction of flows in baffled stirred vessels: A comparison of alternative modeling approaches 显示文摘 | Brucato A Ciofalo M Grisafi F | 1998 | Chemical Engineering Science1998，53，： | 1 |
| 18 | Effect of R3487/MEM3454, a novel nicotinic alpha7 receptor partial ag- onist and 5-HT3 antagonist on sustained attention in rats显示文摘 | Rezvani AH Kholdebarin E Brucato FH | 2009 | Prog Neuropsychopharmacol Biol Psychiatry2009，33，： | 1 |
| 19 | Numerical simulations of the dependency of flow pattern on impeller clearance in stirred vessels显示文摘 | Montante G Lee K C Brucato A | 2001 | Chemical Engineering Science2001，56，： | 1 |
| 20 | State of the art: Reproduction and pregnancy in rheumatic diseases 显示文摘 | Stensen M Andreoli L Brucato A | 2015 | Autoimmun Rev2015，14，5： | 1 |
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