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| 1 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 2 | Medical training fails to prepare providers to care for patients with chronic hepatitis B infection显示文摘AIM: To investigate physicians' knowledge including chronic hepatitis B(CHB) diagnosis, screening, and management in various stages of their training.METHODS: A voluntary 20-question survey was administered in Santa Clara County, CA where Asian and Pacific Islanders(API) account for a third of the population. Among the 219 physician participants,there were 63 interns, 60 second-year residents, 26 chief residents and 70 attending physicians. The survey asked questions regarding respondents' demographics,general hepatitis B virus knowledge questions(i.e.,transmission, prevalence, diagnostic testing, prevention,and treatment options), as well as, self-reported practice behavior and confidence in knowledge.RESULTS: Knowledge about screening and managing patients with CHB was poor: only 24% identified the correct tests to screen for CHB, 13% knew the next steps for patients testing positive for CHB, 18% knew the high prevalence rate among API, and 31% knew how to screen for liver cancer. Wald chi-square analysis determined the effect of training level on knowledge; in all cases except for knowledge of liver cancer screening(p = 0.0032), knowledge did not significantly increase with length in residency training or completion of residency.CONCLUSION: Even in a high-risk region, both medical school and residency training have not adequatelyprepared physicians in the screening and management of CHB. | Stephanie D Chao Bing-Mei Wang Ellen T Chang Li Ma Samuel K So | 2015 | World Journal of Gastroenterology2015，21，22： | 2 |
| 3 | Effects of Adalimumab Therapy on Incidence of Hospitalization and Surgery in Crohn’s Disease: Results From the CHARM Study显示文摘 | Brian G. Feagan Remo Panaccione William J. Sandborn Geert R. D’Haens Stefan Schreiber Paul J. Rutgeerts Edward V. Loftus Kathleen G. Lomax Andrew P. Yu Eric Q. Wu Jingdong Chao Parvez Mulani | 2008 | Gastroenterology2008，，5： | 2 |
| 4 | Juglone, an inhibitor of the peptidyl-prolyl isomerase Pinl ,also directly blocks transcription 显示文摘 | CHAOS H GREENLEAF A L PRICE D H | 2001 | Nucl Acids Res2001，29，3： | 1 |
| 5 | Non-planar dynamic modeling for the optical disk drive spindles equipped with an automatic balancer显示文摘 | Chao P C Huang Y D Sung C K | 2003 | Mechanism and Machine Theory2003，38，： | 1 |
| 6 | A young RNA polymerase Ⅱ holoenzyme contains SWI/SNF regulators involved in chromatin remodeling显示文摘 | WILSO C J CHAO D M Imbelzano A N | 1996 | Cell1996，84，： | 1 |
| 7 | A previously unknown zinc finger protein DST regulates drought and salt tolerance in rice via stomatal aperture control 显示文摘 | Huang X Y Chao D Y Gao ] P | 2009 | Genes Development2009，23，15： | 1 |
| 8 | Study of wire bonding looping formation in the electronic packaging process using the three-dimensional finite element method显示文摘 | Liu D S Chao Y C Wang C H | 2004 | Finite Elements in Analysis and Design2004，40，3： | 1 |
| 9 | Dioxin stimulates RANTES expression in an in-vitro model of endometriosis显示文摘 | Zhao D Pritts EA Chao VA | 2002 | Mol Hum Reprod2002，8，9： | 1 |
| 10 | Juglone, an inhibitor of the peptidyl-prolyl isomerase Pinl, also directly blocks transcription显示文摘 | CHAOS H GREENLEAF A L PRICE D H | 2001 | Nucleic Acids Res2001，29，3： | 1 |
| 11 | R-curve behavior and flaw insensitivity of Ce-TZP/Al2O3 composite显示文摘 | Ramachandran N Chao L Y Shetty D K | | Journal of the American Ceramic Society0，176，4： | 1 |
| 12 | Immunolocalization and regulation of the chemokine RANTES in human endometrial and endometriosis and cells显示文摘 | Hornung D Ryan IP Chao VA | 1997 | J Clin Endocrinol Metab1997，82，： | 1 |
| 13 | 显示文摘 | Lu X F Mao H Chao D M | 2007 | Materials Letters2007，61，6： | 1 |
| 14 | A previously unknown zinc finger protein, DST, regulates drought and salt tolerance in rice via stomatal aperture control显示文摘 | Huang X Chao D Gao J | 2009 | Genes & Development2009，23，15： | 1 |
| 15 | Knowing when to grow:signals regulating bud dormancy显示文摘 | HORVATH D P ANDERSON J V CHAO W S FOLEY M E | 2003 | Trends in Plant Science2003，8，： | 1 |
| 16 | Human cytomegalovirus-in- hibitory flavouoids: Studies on antiviral activity and mechanism of action显示文摘 | Evers D L Chao C F Wang X | 2005 | Antiviral Res2005，68，3： | 1 |
| 17 | Collecting duct renal cell carci- noma:clinical study of a rare tumor 显示文摘 | Chao D Zisman A Pantuck A J | 2002 | J Urol2002，167，1： | 1 |
| 18 | A Long Intrudingly Investigation of New Comer Expectations, Early Socialization out Comes, and Than Overrating Effects Froe Development factors 显示文摘 | Major D A Kozlowski S W J Chao G | 1995 | Journal of Applied Psychology1995，80，3： | 1 |
| 19 | IL-1 beta induction of RANTES (regulated upon activation, normal T cell expressed and secreted) chemokine gene expression in endometriotic stromal cells depends on a nuclear factor- kappaB site in the proximal promoter 显示文摘 | Lebovic D I Chao V A Martini J F | 2001 | Clin Endocrinol Metab2001，86，10： | 1 |
| 20 | Lay Theory of Race Affects and Moderates Asian Ameri- cans' Responses Toward American Culture 显示文摘 | No S Hong Y Y Liao H Y Lee K Wood D Chao M M | 2008 | Journal of Personality and Social Psychology2008，，95： | 1 |
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