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| 1 | Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial显示文摘 | Kris V Kowdley Eric Lawitz Israel Crespo Tarek Hassanein Mitchell N Davis Michael DeMicco David E Bernstein Nezam Afdhal John M Vierling Stuart C Gordon Jane K Anderson Robert H Hyland Hadas Dvory-Sobol Di An Robert G Hindes Efsevia Albanis William T Symo | 2013 | The Lancet2013，，9883： | 3 |
| 2 | Clinical significance of'anti-HBc alone'in human immunodeficiency virus-positive patients显示文摘AIM:To determine the prevalence and clinical relevance of isolated antibodies to hepatitis B core antigen as the only marker of infection('anti-HBc alone')among human immunodeficiency virus(HIV) type-1 infected patients.Occult hepatitis B infection frequency was also evaluated. METHODS:Three hundred and forty eight histories from 2388 HIV-positive patients were randomly reviewed.Patients with serological markers of hepatitis B virus(HBV)infection were classified into three groups:past hepatitis,'anti-HBc alone'and chronic hepatitis.Determination of DNA from HBV,and RNA and genotype from hepatitis C virus(HCV)were performed on'anti-HBc alone'patients. RESULTS:One hundred and eighty seven(53.7%) HIV-positive patients had markers of HBV infection: 118 past infection(63.1%),14 chronic hepatitis (7.5%)and 55'anti-HBc alone'(29.4%).Younger age[2.3-fold higher per every 10 years younger;95% confidence intervals(CI)1.33-4.00]and antibodies to HCV infection[odds ratio(OR)2.87;95%CI 1.10-7.48]were factors independently associated with the'anti-HBc alone'pattern.No differences in liver disease frequency were detected between both groups. Serum levels of anti-HBs were not associated with HCV infection(nor viral replication or HCV genotype),or with HIV replication or CD4 level.No'anti-HBc alone' patient tested positive for HBV DNA. CONCLUSION:'Anti-HBc alone'prevalence in HIVpositive patients was similar to previously reported data and was associated with a younger age and with antibodies to HCV infection.In clinical practice,HBV DNA determination should be performed only in those patients with clinical or analytical signs of liver injury. | M~aTeresa Pérez-Rodríguez Bernardo Sopea Manuel Crespo Alberto Rivera Teresa González del Blanco Antonio Ocampo César Martínez-Vázquez | 2009 | World Journal of Gastroenterology2009，15，10： | 2 |
| 3 | Computerized physician order entry‐based system to prevent HBV reactivation in patients treated with biologic agents: The PRESCRIB project显示文摘 | Blanca Sampedro Cándido Hernández‐López José Ramón Ferrandiz Aitziber Illaro Emilio Fábrega Antonio Cuadrado Paula Iruzubieta Susana Menéndez Joaquín Cabezas Javier Crespo | 2014 | Hepatology2014，，1： | 2 |
| 4 | Comparison between rotary and manual instrumentation in primary teeth显示文摘 | Crespo S Cortes O Garcia C | 2008 | J Clin PediatrDent2008，32，4： | 1 |
| 5 | The digesrive tract of the amberjack Seriola dumerili,Risso:a light and scanning electron microscope study显示文摘 | GRAU A CRESPO S SARASQUETE M C | 1992 | Journal of Fish Biolo gy1992，41，： | 1 |
| 6 | Pathology teach and tell: eosinophilic granuloma 显示文摘 | Khalil F K Wallis Crespo M C Gilbert Barness E | 2004 | Fetal Pediatr Pathol2004，23，4： | 1 |
| 7 | Superovulation and in vitro oocyte maturation in three species of mice (Mus musculus,Mus spretus and Mus spicilegus)显示文摘 | Martín-Coello J González R Crespo C | 2008 | Theriogenology2008，70，6： | 1 |
| 8 | Extraction and re- extraction of phenylalanine by cationic reversed micelles in hollow fibre contactors显示文摘 | CARDOSO M M VIEGAS R M C CRESPO J P S G | 1999 | Journal of Membrane Scince1999，156，2： | 1 |
| 9 | State-of-The-Art of Classical SPH for Free-Surface Flows显示文摘 | Rogers B D Dalrymplc R A Crespo A J C | 2010 | Journal of Hydraulic Re- search Extra Issue2010，，48： | 1 |
| 10 | Development of a proton-transfer reaction ion trap mass spectrometer: Online detection and analysis of volatile organic compounds显示文摘 | Steeghs M M L Sikkens C Crespo E | 2007 | International Journal of Mass Spectr ometry2007，262，12： | 1 |
| 11 | Modifiable and nonmodifiable factors associated with osteoporosis in postmenopausal women:results from the Third National Health and Nutrition Examination Survey, 1988-1994显示文摘 | Snelling AM Crespo C J Schaeffer M | 2001 | J Womens Health Gend Based Med2001，10，1： | 1 |
| 12 | An enhanced automatic algorithm for estimation of respiratory variations in arterial pulse pressure during regions of abrupt hemodynamic changes显示文摘 | Ahoy M Crespo C Austin D | 2009 | IEEE Trans Biomed Eng2009，56，： | 1 |
| 13 | Dioxins sources and current remediation technologies-A review显示文摘 | Kulkarni K S Crespo J G Afonso C A M | 2008 | EnvironmentInternational2008，34，： | 1 |
| 14 | Lack of association between clinical and Cognitive change in first - episode psychosis : the first 6 weeks of treatment 显示文摘 | Gonz61ez - Blanch C Crespo - Facorro B Alvarez - Jim6nez M | 2008 | Can J psychiatry2008，53，12： | 1 |
| 15 | Modifiable and nonmodifiab factors associated with osteoporosis in postmenopausal women:results from the Third National Health an d Nutrition examination Survey显示文摘 | Snelling AM Crespo C J Schaefer M | | 0，，02： | 1 |
| 16 | Direct determination of cobalt and zinc in samples of different volatility by means of solid sampling-graphite furace atomic absorption spectrometry 显示文摘 | Belarra M A Crespo C Martinez-Garbayo M P | 2003 | Spectrochim Acta B2003，58，10： | 1 |
| 17 | Simultaneous removal of perchlorate and nitrate from drinking water using the ion exchange membrane bioreactor concept显示文摘 | Matos C T Velizarov S Crespo J G | 2006 | Water Research2006，40，： | 1 |
| 18 | Green water overtopping analyzed with a SPH model显示文摘 | Gomez-Gesteira M Cerqueiro D Crespo C | 2005 | Ocean Engineering2005，32，： | 1 |
| 19 | The procurement of strategic parts:Analysis of a portfolio of contracts with suppliers using a system dynamics simulation model显示文摘 | Crespo A Blanchar C | 2004 | International Journal of Production Economics2004，88，1： | 1 |
| 20 | An Inference En gine Based on Fuzzy Logic for Uncertain and Imprecise Ex pert Reasoning显示文摘 | D'Aquila R O Crespo C Mate JL | 2002 | Fuzzy Sets and Systems2002，129，2： | 1 |
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