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| 1 | Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI显示文摘 | Wang L Zang Y He Y Liang M Zhang X Tian L Wu T Jiang T Li K | 2006 | 中国生物学文摘2006,20,10: | 84 |
| 2 | Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non-Small-Cell Lung Cancer(摘要)显示文摘 | Hu, ZB Chen, X Zhao, Y Tian, T Jin, GF Shu, YQ Chen, YJ Xu, L Zen, K Zhang, CY Shen, HB | 2010 | 南京医科大学学报(自然科学版)2010,30,7: | 141 |
| 3 | Viral and host causes of fatty liver in chronic hepatitis B显示文摘AIM: To investigate the viral and host causes of fatty liver in chronic hepatitis B patients and the role of fat deposits in liver damage.METHODS: A total of 164 patients (113 males and 51 females, average age 35±11.3 years, and range 10-62 years) with previously untreated chronic hepatitis B were included in the study. The patients were divided into two groups depending on the result of liver biopsy: group without steatosis (100 patients with <5% hepatosteatosis) and group with steatosis (64 patients with >5% hepatosteatosis). The groups were compared in terms of gender, body mass index (BMI), liver enzymes (ALT, AST, ALP, GGT), cholesterol, triglyceride, HBeAg, viral load, and histological findings. In the group with steatosis, the patients were subdivided depending on the degree of steatosis into mild group (45 patients with 5-24% steatosis), and severe group (19 patients with >25% steatosis). RESULTS: In the group of chronic hepatitis B with steatosis, the mean age, BMI, cholesterol, and triglyceride levels were significantly higher than those in the group without steatosis (P<0.05). Steatosis was found in 53 (46.9%) of male patients and 11 (22%) of female patients (P<0.05). No significant difference was found in the positivity of ALT, AST, ALP, GGT, HBeAg, viral load, histological activity index (HAI) and stage between the two groups (P>0.05). In the group with severe steatosis, the BMI was significantly higher than that in the group with mild steatosis (P<0.05). No significant difference was found in the other parameters between the groups (P>0.05). CONCLUSION: Steatosis in chronic hepatitis B appears to be a result of metabolic factors of the host rather than the effect of viruses. Steatosis is unrelated to the HAI and degree of fibrosis, which are considered as the histological indicators of liver damage. | Emin Altiparmak Seyfettin K(o|¨)klü Mesut Yalinkilic Osman Yüksel Bahattin Cicek Ertugrul Kayacetin Tülin Sahin | 2005 | World Journal of Gastroenterology2005,11,20: | 52 |
| 4 | 血管内超声去肾交感神经术治疗高血压:一项多中心,国际,单盲,随机,假手术对照试验显示文摘早期研究表明,基于射频的去肾交感神经术可降低中度高血压患者的血压。研究者研究了在没有使用抗高血压药物的情况下,使用血管内超声去。肾交感神经术是否会降低高血压患者的动态血压。 | 刘青 叶鹏 Azizi M Schmieder RE Mahfoud F Weber MA Daemen J Davies J Basile J Kirtane AJ Wang Y Lobo MD Saxena M Feyz L Rader F Lurz P Sayer J Sapoval M Levy T Sanghvi K Abraham J Sharp ASP Fisher NDL Bloch MJ Reeve-Stoffer H Coleman L Mullin C Mauri L | 2018 | 中华高血压杂志2018,26,10: | 27 |
| 5 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012,45,5: | 22 |
| 6 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013,11,3: | 23 |
| 7 | Modified boron neutron capture therapy for malignant gliomas performed using epithermal neutron and two boron compounds with different accumulation mechanisms: an efficacy study based on findings on neuroimages显示文摘 | Miyatake S Kawabata S Kafimoto Y Aoki A Yokoyama K Yamada M Kuroiwa T Tsuji M Imahori Y Kirihata M Sakurai Y Masunaga S Nagata K Maruhashi A Ono K | 2005 | 中国神经肿瘤杂志2005,3,4: | 14 |
| 8 | 腰椎椎间孔狭窄引起静息性腿痛显示文摘腰椎椎间孔狭窄(foraminal stenosis,FS)诊断困难,往往使腰椎管狭窄(canal stenosis,CS)常规手术的预后不尽如人意,有学者认为,近60%的术后持续疼痛来自于腰椎FS。 | Yamada K Aota Y Higashi T 杨庆磊 尹庆水 | 2014 | 中国骨科临床与基础研究杂志2014,6,3: | 11 |
| 9 | 根据血压等级确定脑卒中和冠状动脉粥样硬化性心脏病死亡的终生风险:日本EPOCH(观察队列的心血管预防证据)研究显示文摘在亚洲人群中.很少研究关注根据血压分类确定脑卒中和冠状动脉粥样硬化性心脏病(coronary heartdisease,CHD)的终生风险。该研究旨在用一个包含个体参与者数据的荟萃分析大数据库来评估它。该荟萃分析纳入来源于13个队列的107 737名日本人(男性占42.4%,平均年龄55.1岁)。在平均(15.2±5.3)年(1 559 136人年)的随访期.1922人死于脑卒中,913人死于CHDO研究者在调整其他死亡危险因素后估计风险。 | 陈嘉睿(译) 练桂丽(审校) Satoh M Ohkubo T Asayama K Murakami Y Sugiyama D Yamada M Saitoh S Sakata K Irie F Sairenchi T Ishikawa S Kiyama M Ohnishi H Miura K Imai Y Ueshima H Okamura T EPOCH-JAPAN research group | 2019 | 中华高血压杂志2019,27,4: | 9 |
| 10 | Cranial base chordoma——long term outcome and review of the literature显示文摘BACKGROUND: The purpose of this study is to clarify the latest long-term therapeutic result for cranial base chordomas.We are seeking an improvement of long term therapeutic outcome through a review of cranial base chordomas treated in | Yoneoka Y Tsumanuma I Fukuda M Tamura T Morii K Tanaka R Fujii Y | 2008 | 中国神经肿瘤杂志2008,6,3: | 9 |
| 11 | 全科诊疗中家庭血压监测的夜间血压是心血管事件的一个独立预测因素显示文摘研究者开发了一种新型的自动家庭血压监测方法,可以在数天内重复测量睡眠血压。该研究旨在评估患者采用家庭血压测量计所测的夜间血压预测心血管事件发生的能力。采用基于全国性的日本血压晨峰-家庭血压(Japan morning surge-home blood pressure,J-HOP)夜间血压研究的数据,研究纳入有心血管病史或危险因素的日本全科诊疗患者2545例(平均年龄63岁,83%服用降压药)。采用Cox比例风险模型评估家庭夜间血压(采用家庭自动电子血压计在夜间2:00,3:00及4:00时测量)与发生心血管病(包括冠状动脉粥样硬化性心脏病与脑卒中)的关系。诊室、家庭清晨及家庭夜间收缩压/舒张压分别为(140±15)/(82±10)、(137±15)/(79±10)及(121±15)/(70±9)mmHg(1mmHg=0.133kPa)。 | 赵狄(摘译) 练桂丽(审校) Kario K Kanegae H Tomitani N Okawara Y Fujiwara T Yano Y Hoshide S | 2019 | 中华高血压杂志2019,27,6: | 8 |
| 12 | Purified human bone marrow multipotent mesenchymal stem cells regenerate infarcted myocardium in experimental rats显示文摘 | Zhang S Jia Z Ge J Gong L Ma Y Li T Guo J Chen P Hu Q Zhang P Liu Y Li Z Ma K Li L Zhou C | 2006 | 中国生物学文摘2006,20,5: | 5 |
| 13 | 血流介导的血管舒张,硝酸甘油诱导的血管舒张,基线肱动脉直径,充血剪切应力与心血管病危险因素之间的相关性显示文摘血流介导的血管舒张功能(flow-mediated vasodilation,FMD)已被用于评估内皮功能。充血性剪切应力(hyperemic shear stress,HSS,一种FMD的刺激因素)、硝酸甘油诱导的血管舒张(nitroglycerine-induced vasodilation,NID,非内皮依赖性血管舒张指数)以及基线肱动脉直径(brachial artery diameter,BAD)也参与血管舒张反应。 | 刘青 叶鹏 Maruhashi T Iwamoto Y Kajikawa M Oda N Kishimoto S Matsui S Hashimoto H Aibara Y Yusoff FM Hidaka T Kihara Y Chayama K Noma K Nakashima A Goto C Hida E Higashi Y | 2018 | 中华高血压杂志2018,26,1: | 5 |
| 14 | Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS.显示文摘 | Ma Q Li Y Du J Liu H Kanazawa K Nemoto T Nakanishi H Zhao Y | 2006 | 中国生物学文摘2006,20,9: | 4 |
| 15 | 吸烟状况与急性缺血性脑卒中后功能结局的关系显示文摘吸烟是脑卒中的既定危险因素;然而,脑卒中前吸烟状态是否会影响急性缺血性脑卒中的临床预后尚不确定。该研究旨在阐明吸烟状态与急性缺血性脑卒中后功能预后的关系。研究者获取一项基于日本多中心医院的脑卒中登记资料,调查了2007年7-12月期间住院的10825例急性缺血性脑卒中患者,这些患者在脑卒中发作之前生活能够自理。吸烟状况分为从未吸烟者(不吸烟者),曾经吸烟者和现在吸烟者。临床结局包括3个月时功能转归不良(改良的Rankin量表评分≥2)和功能性依赖(改良的Rankin量表评分2~5)。 | 刘青(译) 刘莉(摘、审校) Matsuo R Ago T Kiyuna F Sato N Nakamura K Kuroda J Wakisaka Y Kitazono T | 2020 | 中华高血压杂志2020,28,2: | 4 |
| 16 | Power management unit chip design for automobile active-matrix organic light-emitting diode display module显示文摘A power management unit (PMU) chip supplying dual panel supply voltage, which has a low electro-magnetic interference (EMI) characteristic and is favorable for miniaturization, is designed. A two-phase charge pump circuit using external pumping capacitor increases its pumping current and works out the charge-loss problem by using bulk-potential biasing circuit. A low-power start-up circuit is also proposed to reduce the power consumption of the band-gap reference voltage generator. And the ring oscillator used in the ELVSS power circuit is designed with logic devices by supplying the logic power supply to reduce the layout area. The PMU chip is designed with MagnaChip’s 0.25 μm high-voltage process. The driving currents of ELVDD and ELVSS are more than 50 mA when a SPICE simulation is done. | KIM J H PARK J H KIM J H CAO T V LEE T Y BAN H J YANG K KIM H G HA P B KIM Y H | 2009 | Journal of Central South University2009,16,4: | 4 |
| 17 | 厚壁奥氏体焊缝超声波检测之探究(英文)显示文摘由于奥氏体焊缝中材料性能的各向异性和微观组织结构的不同,奥氏体焊缝的超声波检测是非常困难的。超声波在奥氏体焊缝中会沿金属结晶方向发生偏转,并在焊缝边界上发生散射。过去十年来,人们开发了多种模拟各向异性材料中声波传播的仿真工具。本文则以常规超声波检测方法为基础,将声线跟踪法和弹性动力学有限积分技术(EFIT)相结合,应用于含晶间应力腐蚀裂纹的厚壁奥氏体焊缝中,其结果显示声线跟踪法和弹性动力学有限积分技术(EFIT)结合应用,有助于超声波检测参数的选取。 | Han T Y Khler B Schmitz V Zimmer A Langenberg K J | 2009 | 无损检测2009,31,11: | 3 |
| 18 | Changes in hippocampal connectivity in the early stages of Alzheimer's disease: evidence from resting state fMRI显示文摘 | Wang L Zang Y He Y Liang M Zhang X Tian L Wu T Jiang T Li K | 2006 | 中国生物学文摘2006,20,8: | 3 |
| 19 | 云南省农村地区男男性接触者与HIV相关的风险行为显示文摘目的探讨中国农村地区男男性接触者(MSM)与艾滋病病毒(HIV)相关的风险行为的具体特点和问题。方法采用半结构化深度访谈的方式进行定性研究。通过一个当地的MSM联系网络,以滚雪球和相互转告的方式招集了24名访谈对象。主要测量指标是与HIV有关的风险行为的上升情况。结果在中国农村地区,风险行为、社会歧视、独生子女政策以及传统中医的观念,在HIV的传播中都起着重要的作用。在中国,许多MSM过着双重生活;调查显示,安全套的使用情况也是因人而异,使风险行为'合理化'的意图是决定是否使用安全套的主要因素;就泌尿生殖系统的问题主动寻求医疗帮助的现象很不普遍,而现有卫生系统以及医务人员对此问题表现出来的不敏感,也进一步加剧了这种现象。结论在资源匮乏的农村地区,MSM人群存在着HIV流行的趋势,并有向普通人群传播的危险。 | 张建波 黄志威 T S K Kong D C Y Ling | 2007 | 中国艾滋病性病2007,13,5: | 3 |
| 20 | 钻孔千斤顶压裂测量技术的发展和原地测量显示文摘为了测量距地表1 000m以下位置的地壳应力状态,我们研究并开发了钻孔千斤顶压裂技术。技术的原理是:当钻孔千斤顶对钻孔壁加载时,与钻孔轴向平行的方向将会产生两个相对的新裂隙;卸载之后,如果千斤顶对钻孔壁的同一个地方进行施压,这对裂隙将会再次张开。与钻孔轴向垂直的平面上的两个主应力的大小和方向分别是由重张压力和裂隙的方向决定的。这个技术与水压致裂法相似。因此,测量深度没有理论上的限制。这个技术的特点就是它可以产生一对任意方向的轴向裂隙,可以测量裂隙张开的位移大小,根据测量结果可以精确计算重张压力的大小。在实地测试中,先用水压致裂法形成裂隙,再用钻孔压力千斤顶法加以与水压近似相等的压力值使之重张。本文介绍了我们的数值分析结果、实验室实验和现场测试。 | Yokoyama T Ogawa K Sano O Hirata A Mizuta Y 徐伟(译) 张雷 姚瑞 沙鹏(校) | 2011 | 国际地震动态2011,,1: | 3 |