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| 1 | Current protective strategies in liver surgery显示文摘During liver resection surgery for cancer or liver transplantation,the liver is subject to ischaemia (reduction in blood flow) followed by reperfusion (restoration of blood flow),which results in liver injury [ischemiareperfusion (IR) or IR injury]. Modulation of IR injury can be achieved in various ways. These include hypothermia,ischaemic preconditioning (IPC) (brief cycles of ischaemia followed by reperfusion of the organ before the prolonged period of ischaemia i.e. a conditioning response),ischaemic postconditioning (conditioning after the prolonged period of ischaemia but before the reperfusion),pharmacological agents to decrease IR injury,genetic modulation of IR injury,and machine perfusion (pulsatile perfusion). Hypothermia decreases the metabolic functions and the oxygen consumption of organs. Static cold storage in University of Wisconsin solution reduces IR injury and has prolonged organ storage and improved the function of transplanted grafts. There is currently no evidence for any clinical advantage in the use of alternate solutions for static cold storage. Although experimental data from animal models suggest that IPC,ischaemic postconditioning,various pharma-cological agents,gene therapy,and machine perfusion decrease IR injury,none of these interventions can be recommended in clinical practice. This is because of the lack of randomized controlled trials assessing the safety and efficacy of ischaemic postconditioning,gene therapy,and machine perfusion. Randomized controlled trials and systematic reviews of randomized controlled trials assessing the safety and efficacy of IPC and various pharmacological agents have demonstrated biochemical or histological improvements but this has not translated to clinical benefit. Further well designed randomized controlled trials are necessary to assess the various new protective strategies in liver resection. | Kurinchi S Gurusamy Hector D Gonzalez Brian R Davidson | 2010 | World Journal of Gastroenterology2010，16，48： | 7 |
| 2 | Cholangiocarcinoma显示文摘 | Shahid A Khan Howard C Thomas Brian R Davidson Simon D Taylor-Robinson | 2005 | The Lancet . 2005 (9493)2005，，： | 3 |
| 3 | Cholangiocarcinoma显示文摘 | Shahid A Khan Howard C Thomas Brian R Davidson Simon D Taylor-Robinson | 2005 | The Lancet2005，，9493： | 2 |
| 4 | Diffusion and chemical activity of Zr-Sn and Zr-Ti systems 显示文摘 | ZEE R H WATTERS J F DAVIDSON R D | 1986 | Physical Review B1986，34，10： | 1 |
| 5 | The Retail Life Cycle显示文摘 | DAVIDSON W R BATES A D BASS S J | 2002 | Retailing:The Evolution and Development of Retailing2002，55，6： | 1 |
| 6 | 显示文摘 | Uhlmann D R Suratwala T Davidson K | 1997 | J Non-Cryst Solids1997，218，： | 1 |
| 7 | Effects of atracurium on intraocuiar pressure, eye position, and blood pressure in eucapnic and phyocapnic isoflurane-anes- thetized dogs 显示文摘 | Mcmurphy R M Davidson H J Hodgson D S | 2004 | Am J Vet Res2004，65，5： | 1 |
| 8 | The parp inhibitor abt -888 synergizes irinotecan treatment of colon cancer cell lines显示文摘 | DAVIDSON D WANG Y ALOYZ R | 2013 | Invest New Drugs2013，31，2： | 1 |
| 9 | Drawing graphs nicely using simula- ted annealing显示文摘 | Davidson R Harel D | 1996 | ACM Transactions on Graphics(TOG)1996，15，4： | 1 |
| 10 | A parametric study of droplet deformation through a microfluidic contraction: Low viscosity Newtonian droplets 显示文摘 | HARVIE D J E DAVIDSON M R COOPER WHITE J J | 2006 | Chemical Engineering Science2006，61，51： | 1 |
| 11 | GUDMAP :the genitourinary developmental molecular anatomy project显示文摘 | McMahon A P Aronow B J Davidson D R | 2008 | Journal of the American Society of Nephrolov2008，19，4： | 1 |
| 12 | Life prediction methodology for composite structures, Part Ⅰ-constant amplitude and two-stress level fatigue显示文摘 | SCHAFF J R DAVIDSON B D | 1997 | Journal of Composite Materials1997，31，： | 1 |
| 13 | Soil water content and temperature as independent or confounded factors controlling soil respiration in a temperate mixed hardwood forest显示文摘 | Davidson E A Belk & R D Boone | 1998 | Global Change Biology1998，4，： | 1 |
| 14 | Starvation period and age affect the response of female Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) to odor and visual cues 显示文摘 | Davidson M M Butler R C Teulon D A J | 2006 | Journal of Insect Physiology2006，52，： | 1 |
| 15 | Immunomodulatory properties of defensins and cathelicidins显示文摘 | Bowdish D M Davidson D J Hancock R E | 2006 | Curr Top Microbiol Immunol2006，306，： | 1 |
| 16 | A re-evaluation of the role of host defence peptides in mammalian immunity显示文摘 | Bowdish D M E Davidson D J Hancock R E W | 2005 | Current Protein and Peptide Science2005，6，1： | 1 |
| 17 | The mecha- nism of intergranular stress corrosion cracking of sensitised austenitic stainless steel in dilute thiosulphate solution 显示文摘 | Wells D B Stewart J Davidson R | 1992 | Corros Sci1992，33，： | 1 |
| 18 | Life Prediction Methodology for Composite Structures: Part I- constant Amplitude and Two-stress Level Fatigue 显示文摘 | Schaff J R Davidson B D | 1997 | Journal of Composite Materials1997，31，2： | 1 |
| 19 | Evidence of tick-borne organisms in mule deer (Odocoileus hemionus)from the westem United States 显示文摘 | Yabsley M J Davidson W R Stallknecht D E | 2005 | Vector Borne Zoonotic Dis2005，5，4： | 1 |
| 20 | Applications of Ultrasound to Organic Chemistry 显示文摘 | Davidson R S Safdar A Spencer J D | 1987 | Ultrasonics1987，25，1： | 1 |
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