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	题名	作者	年代	出处	被引量
1	Short and long term fate of human AMSC subcutaneously injected in mice显示文摘AIM:To study the ability of human adipose-derived mesenchymal stem cells(AMSCs)to survive over the short and long term,their biodistribution and their biosafety in vivo in tumor-prone environments.METHODS:We subcutaneously injected human AMSCs from different human donors into immunodeficient SCID mice over both short-(2 and 4 mo)and long-(17 mo)term in young,and aged tumor-prone mice.Presence of human cells was studied by immunohistochemistry and polymerase chain reaction analysis in all organs of injected mice.RESULTS:Subcutaneously injected AMSCs did not form teratomas at any time point.They did not migrate but remained at the site of injection regardless of animal age,and did not fuse with host cells in any organ examined.AMSCs survived in vivo for at least 17 mo after injection,and differentiated into fibroblasts of the subdermic connective tissue and into mature adipocytes of fat tissue,exclusively at the site of injection.CONCLUSION:Our results support the assertion that AMSC may be safe candidates for therapy when injected subcutaneously because of their long term inability to form teratomas.	Pilar López-Iglesias Alejandro Blázquez-Martínez Jorge Fernández-Delgado Javier Regadera Manuel Nistal Maria P De Miguel	2011	World Journal of Stem Cells2011，3，6：	5
2	Rho kinase blockade prevents inflammation via nuclear factor κB inhibition: evidence in Crohn’s disease and experimental colitis显示文摘	Jean-Pierre Segain Diane Raingeard de la Blétière Vincent Sauzeau Arnaud Bourreille Gréory Hilaret Chrystelle Cario-Toumaniantz Pierre Pacaud Jean-Paul Galmiche Gervaise Loirand	2003	Gastroenterology2003，，5：	2
3	Domain motions in bacteriophage T4 lysozyme: a comparison between molecular dynamics and crystallographic date 显示文摘	De Groot BL Hayward S van Aahen DM	1998	Proteins1998，31，2：	1
4	An Approximate Analysis of Dry-frction-induced Stick-slip vibrations by a Smoothing Procedure 显示文摘	Van de Vrande BL Van Campen DH Kraker ADe	1999	Nonlinear Dynamics1999，19，1：	1
5	The worldwide preva- lence of ADHD: A systematic review and metaregression analysis 显示文摘	Polanczyk G de Lima MS Horta BL	2007	Am J Psychiatry2007，164，6：	1
6	Treatment with the radiolabeled somatostatin analog octreotate toxicity, efficacy, and survival 显示文摘	Kwekkeboom D J de Herder WW Kam BL	2008	J Clin On- col2008，26，13：	1
7	HIV-1discordant couples in sub Saharan Africa:explanations and implications for high rates of discordancy显示文摘	Cuthrio BL de Bruyn C Farquhar C	2007	Current HIV Research2007，5，4：	1
8	The worldwide prevalence of ADHD: a systematic review and metaregression analysis显示文摘	Polanczyk G de Lima MS Horta BL	2007	Am J Psychiatry2007，164，6：	1
9	Mild preoperative renal dysfunction as a predictor of long-term clinical outcome after coronary bypass surgery显示文摘	van de Wal RMA van Brussel BL Voors AA	2005	J Thorac Cardiovasc Surg2005，29，2：	1
10	Quality of life of idiopathic pulmonary fibrosis patients显示文摘	De Vries J Kessels BL Drent M	2001	Eur Respir J2001，17，5：	1
11	Immunosuppressive properties of mesenchymal stem cells:advances and applications显示文摘	De Miguel MP Fuentes-Julián S Blázquez-Martínez A	2012	Curr Mol Med2012，12，5：	1
12	Genetic Fibrillinopathies:new insights in molecular diagnosis and clinical management 显示文摘	LOEYS BL MATTHYS DM DE PAEGE AM	2003	Acta Clin Belg2003，58，1：	1
13	Struetion and fuction of water channels 显示文摘	Fujiyoshi Y Mitsuoka K de Groot BL	2002	Curr Opin Struct Biol2002，12，4：	1
14	Treatment with the radiolaboled somatostatin analogoctreotate:toxicity,efficacy,and survival显示文摘	Kwekkeboom DJ de Herder WW Kam BL	2008	J Clin Oncol2008，26，13：	1
15	Acute-phase responsiveness of mannose-binding lectin in community-ac-quired pneumonia is highly dependent upon MBL2genotypes显示文摘	Herpers BL Endeman H de Jong BAW	2009	Clin Exp Immunol2009，156，：	1
16	The worldwide prev- alence of ADHD : a systematrie review and metaregression analy- sis显示文摘	Polanczyk G De Lima MS Horta BL	2007	Am J Psychiatry2007，164，6：	1
17	Response of chronic and aggressive periodontitis to treatment显示文摘	Deas DE Mealey BL	2010	Periodontol 20002010，53，：	1
18	The role of femoral venous pressure and femoral venous oxygen saturation in the setting of intra-abdominal hypertension: a pig model 显示文摘	Regli A De Keulenaer BL Hockings LE	2011	Shock2011，35，4：	1
19	Nonoperative management of intra-abdominal hypertension and abdominal compartment syndrome: Evolving concepts 显示文摘	De Keulenaer BL De Waele J J Malbrain ML	2011	Am Surg2011，77，1：	1
20	The timing of prednisolone dosage and its effect on morning stiffness in rheumatoid arthritis 显示文摘	De Silva M Binder A Hazleman BL	1984	Ann Rheum Dis1984，43，6：	1

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