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| 1 | Residual renal function in peritoneal dialysis with failed allograft and minimum immunosuppression显示文摘Immunosuppression(IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function(RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis(PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation. Hemodialysis was initiated via tunneled dialysis catheter(TDC) and IS was gradually withdrawn. Two weeksafter IS withdrawal he developed a febrile illness, which necessitate removal of the TDC and conversion to PD. He was maintained on small dose of tacrolimus(1 mg/d) and prednisone(5 mg/d). Currently(1 year later) he is doing exceedingly well on cycler-assisted PD. Residual urine output ranges between 600-1200 m L/d. Total weekly Kt/V achieved 1.82. RRF remained well preserved in this patient with failed renal allograft with minimal immunosuppressive therapy. This strategy will need further study in well-defined cohorts of PD patients with failed allografts and residual RRF to determine efficacy and safety. | Nadear Elmahi éva Csongrádi Kenneth Kokko Jack R Lewin Jamie Davison Tibor Fülp | 2013 | World Journal of Transplantation2013，3，2： | 5 |
| 2 | Genetic improvement of Trichoderma ability to induce systemic resistance显示文摘The beneficial applications of Trichoderma spp. in agriculture include not only the control of plant pathogens, but also the improvement of plant growth, micronutrient availability, and plant tolerance to abiotic stress. In addition, it has been suggested that these fungi are able to increase plant disease resistance by activating induced systemic resistance (ISR) . The mode of action of these beneficial fungi in the Trichoderma -plant-pathogen interaction are many, complex and not completely understood. Numerous lytic enzymes have been characterized, the encoding genes (ech42 gluc78, nag1 from T. atroviride strain P1) cloned, and their role in biocontrol demonstrated. The corresponding biocontrol-related inducible promoters have been used in a reporter system based on the Aspergillus niger glucose oxidase gene (goxA) to monitor biocontrol activity. Glucose oxidase catalyzes the oxygen-dependent oxidation of D-glucose to D-glucono-1,5-lactone and hydrogen peroxide; this latter compound is known to have an antifungal effect and activate the plant defence cascade, thus increasing resistance to pathogen attack. T. atroviride P1 transformants with various promoters gox were tested as seed coating treatments on bean seeds planted in soil infested with a soilborne fungal pathogen. Successively, the emergent leaves were inoculated with a foliar pathogen to determine the effect of the GOX transformants on biocontrol and resistance to pathogen attack. Inoculations with the P1-GOX transformants not only reduced disease symptoms caused by a soil pathogen, but also the lesions of various foliar pathogens applied far from the Trichoderma colonization, thus activating ISR. A similar approach is being use to genetically improve T. harzianum T22, a rhizosphere competent and commercially marketed strain not transformed yet, by using four different gox gene constructs under the control of constitutive and inducible promoters. Plasmids have been introduced in Trichoderma by protoplasts co-transformation. hygromicin resistant progeny selected, and mitotically stable transformants analysed to confirm the presence of the novel enzyme activity. Progenies are being tested for biocontrol ISR inducing activity. | Ciliento R Woo S L Di Benedetto P Ruocco M Scala F Soriente I Ferraioli S Brunner K Zeilinger S Mach R L Lorito M | 2004 | 浙江大学学报(农业与生命科学版)2004，30，4： | 2 |
| 3 | New simple and rapid method for purification of mesenchy- mal stem cells from the human umbilical cord Wharton jelly显示文摘 | Montanucci P G Basta T Pescara I Pennoni F Di Giovanni and R Calafiore | 2011 | Tis- sue Eng Part A2011，，： | 1 |
| 4 | Rosuvastatin reduces platelet recruitment by inhibiting NADPH oxidase activation显示文摘 | Pignatelli P Carnevale R Di Santo S | 2012 | Biochem Pharmacol2012，84，12： | 1 |
| 5 | New Genera-tion of Linux Meta-installers显示文摘 | Trezentos P Di Cosmo R Lauriere S | | 0，，： | 1 |
| 6 | Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours:a pilot clinical trial显示文摘 | Olioso P Giancola R Di Riti M | 2009 | Hematol Oncol2009，27，3： | 1 |
| 7 | Optimal existence theory for single and multiple positive periodic solutions to functional difference equations显示文摘 | DI QING-jiang O'REGAN D AGARWAL R P | 2005 | Appl Math Letters2005，161，： | 1 |
| 8 | A poly- morphism in the VKORC1 gene is associated with an interindivid- ual variability in the dose anticoagulant effect of warfarin 显示文摘 | D'ANDREA G D'AMBROSIO R L DI PEMA P | 2005 | Blood2005，1，5： | 1 |
| 9 | Effect of thyroid state on H2O2 production by mt liver mitochondria 显示文摘 | Venditti P De Rosa R Di Meo S | 2003 | Mol Cell Endocrinol2003，205，12： | 1 |
| 10 | Control of the growth of zinc-iron phases in the hot-dip galvanizing process 显示文摘 | CULCASI J D SER P R ELSNER C I DI SARLI A R | 1999 | Surf Coat Technol1999，122，1： | 1 |
| 11 | Microneurographic evaluation of sympathetic activity in small fiber neuropathy 显示文摘 | Liguori R Giannoccaro M P Di Stasi V | 2011 | Neurophysiol Clin2011，，122： | 1 |
| 12 | Ablation of atrial fibrillation utilizing robotic catheter navigation in comparison to manual navigation and ablation:single-center experience显示文摘 | Di Biase L Wang Y Horton R Gallinghouse G J Mohanty P Sanchez J | | 0，，： | 1 |
| 13 | (1) H-MR spectroscopy indicates prominent cerebellar dysfunction in benign adult familial myoclonic epilepsy显示文摘 | Striano P Caranci F Di Benedetto R | 2009 | Epilepsia2009，50，： | 1 |
| 14 | Conjunetival epithelium improvement after systemic pilocarpine in patients with Sj~gren's syndrome显示文摘 | Aragona P di Pietro R Spinella R | 2006 | Br J Ophthalmol2006，90，2： | 1 |
| 15 | Needle Artifact Localization in 3T MR Images显示文摘 | Di Maio S P Kacher D F Ellis R E | 2006 | Stud Health Teehnol Inform2006，119，： | 1 |
| 16 | Mechanisms of apoptosis induced by purine nucleosides in astrocytes显示文摘 | Di lorio P Kleywegt S Ciccarelli R | 2002 | Glia2002，38，3： | 1 |
| 17 | Relationship between texture and corrosion resistance in hot-dip galvanized steel sheets显示文摘 | SERE P R CULCASI J D ELSNER C I DI SARLI A R | 1999 | Surface and Coatings Technology1999，122，6： | 1 |
| 18 | Immunotherapy with cytokine induced killer cells in solid and hematopoietic tumours: a pilot clinical trial显示文摘 | OLIOSO P GIANCOLA R DI RITI M | 2009 | Hematol Oncol2009，27，3： | 1 |
| 19 | Clinical application of stereolithographic surgical guides for implant placement:preliminary results显示文摘 | DI GIACOMO G A CURY P R DE ARAUJO N S | 2005 | J Periodontol2005，76，4： | 1 |
| 20 | miR-203 represses 'sternness' by repressing DeltaNp63 显示文摘 | A M Lena R Shalom-Feuerstein P Rivetti di Val Cervo | 2008 | Cell Death Differ2008，15，7： | 1 |
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