|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | CONSORT 2010说明与详述:报告平行对照随机临床试验指南的更新显示文摘大量证据显示随机对照临床试验(randomised controlled trial,RCT)的报告质量不理想。报告不透明,则读者既不能评判试验结果是否真实可靠,也不能从中提取可用于系统综述的信息。最近的方法学分析表明,报告不充分和设计不合理与对治疗效果产生评价偏倚有关。这种系统误差对RCT损害严重,而RCT正是以其能减少或避免偏倚而被视为评价干预措施的金标准。为了提高RCT的报告质量,一个由专家和编辑组成的工作组制定了临床试验报告的统一标准(Consolidated Standards of Reporting Trials,CONSORT)声明。CONSORT声明于1996年首次发表,并于2001年更新。声明由对照检查清单和流程图组成,供作者在报告RCT时使用。许多核心医学期刊和主要国际性编辑组织都已认可CONSORT声明。该声明促进了对RCT的严格评价和解释。2001年,在对CONSORT进行修订时,人们就已经清楚地认识到,解释和说明制定CONSORT声明的原理,有助于研究人员等撰写或评价临床试验报告。一篇CONSORT说明与详述文章于2001年同2001版CONSORT声明一起发表。2007年1月的专家会议之后,对CONSORT声明作了进一步修订并已发表,即'CONSORT2010声明'。这次更新对原版对照检查清单作了文字上的修改,使其更为明晰,并收入了与一些新近才认识到的主题相关的建议,如选择性报告结局产生的偏倚。说明与详述文件旨在加强人们对CONSORT声明的理解、应用和传播,这次也作了大量修订,对每一项新增或更新的清单条目的含义和增改理由进行了解释,提供了优秀的报告实例,还尽可能地提供了相关的经验性研究的参考文献。文中收入了若干流程图实例。'CONSORT2010声明'、其说明与详述文件,以及相关网站(www.consort-statement.org),对于改进随机临床试验报告必将有所裨益。 | David Moher Sally Hopewell Kenneth F Schulz Victor Montori Peter C Gφtzsche P J Devereaux Diana Elbourne Matthias Egger Douglas G Altman 周庆辉 卞兆祥 刘建平 | 2010 | 中西医结合学报2010，8，8： | 318 |
| 2 | Metal Fabrication by Additive Manufacturing Using Laser and Electron Beam Melting Technologies显示文摘Selective laser melting (SLM) and electron beam melting (EBM) are relatively new rapid, additive manufac- turing technologies which can allow for the fabrication of complex, multi-functional metal or alloy monoliths by CAD-directed, selective melting of precursor powder beds. By altering the beam parameters and scan strategies, new and unusual, even non-equilibrium microstructures can be produced; including controlled microstructural architectures which ideally extend the contemporary materials science and engineering paradigm relating structure-properties-processing-performance. In this study, comparative examples for SLM and EBM fabricated components from pre-alloyed, atomized precursor powders are presented. These include Cu, Ti–6Al–4V, alloy 625 (a Ni-base superalloy), a Co-base superalloy, and 17-4 PH stainless steel. These systems are characterized by optical metallography, scanning and transmission electron microscopy, and X-ray diffraction. | Lawrence E. Murr Sara M. Gaytan Diana A. Ramirez Edwin Martinez Jennifer Hernandez Krista N. Amato Patrick W. Shindo Francisco R. Medina Ryan B. Wicker | 2012 | Journal of Materials Science & Technology2012，28，1： | 98 |
| 3 | ATP-dependent chromatin remodeling: genetics, genomics and mechanisms显示文摘用 ATP 水解作用的精力调整染色质结构的 Macromolecular 集会在开发,癌症,和干细胞生物学有关键角色。这个家庭的 ATPases 被 27 人的基因编码并且通常与稳定的几另外的蛋白质被联系,非可交换的子单元。这些建筑群使用的一基本机制被认为是 nucleosomes 的运动或交换调整抄写。然而,最近的基因研究显示染色质 remodelers 可以也涉及在许多细胞的过程期间调整染色质结构的另外的方面。SWI/SNF 家庭特别地看起来在子单元作文和与多细胞体和连接 histones 的外观的进化来临重合的机制经历了一个实质的变化。哺乳动物的 BAF 子单元的这更大的差异的微分用法为特定的房间命运的发展是必要的,包括到到承诺的神经原的 multipotency 的从 pluripotency 的前进。最近的人的基因屏幕表明了 BRG1, ARID1A, BAF155,和 hSNF5 经常在肿瘤被变异,显示 BAF 建筑群也起在癌症的开始或前进的一个关键作用。在开发和癌症为 BAF 和另外的染色质 remodelers 位于基因要求下面的机械学的库是相对未经勘探的并且将是这评论的一个焦点。 | Diana C Hargreaves Gerald R Crabtree | 2011 | Cell Research2011，21，3： | 51 |
| 4 | PBL:教育实践和研究的未来挑战显示文摘本文是一篇有关PBL的评论性研究,根据现代学习理论,作者论述了四个有关学习的原则,解释了这些原则在PBL中的应用,并对已进行的研究进行了评议。 | Diana HJM Dolmans Willem De Grave Ineke HAP Wolfhagen Cees PM van der Vleuten 梅人朗 | 2008 | 复旦教育论坛2008，6，1： | 44 |
| 5 | 西酞普兰及人际心理治疗对合并抑郁症的冠心病患者的影响——加拿大心脏病人群抗抑郁药及心理治疗疗效随机试验(CREATE)显示文摘背景:目前鲜有随机对照试验就冠心病(coronary artery disease,CAD)患者重度抑郁症的治疗效果进行评估,亦无试验同时对抗抑郁药和短期心理治疗进行评估。
目的:在同时患有CAD及重度抑郁症的患者中明确选择性5.羟色胺再摄取抑制剂(西酞普兰)及人际心理治疗(interpersonal psychotherapy,IPT)在减少抑郁症状方面的短期效果。 | Francois Lespérance Nancy Frasure-Smith Diana Koszycki 顾佳(译) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 36 |
| 6 | Gastrointestinal tract(gut) health in the young pig显示文摘An optimally functioning gastrointestinal tract(GIT) clearly is of importance to the overall metabolism,physiology, disease status and performance of pigs of all stages of growth and development.Recently, the‘health’ of the GIT(‘gut health’) has attracted much attention despite the lack of a clear definition to the term or its aetiology, although in broad terms, ‘gut health’ encompasses a number of physiological and functional features including nutrient digestion and absorption, host metabolism and energy generation, a stable and appropriate microbiota/microbiome, defence mechanisms including barrier function and mucosal immune mechanisms, and the interactions between these components.‘Gut health’ in the newlyweaned(young) pig is of obvious interest due to changes in GIT structure and function associated with the post-weaning transition, and more recently to the upsurge in interest in different feed additives as dietary alternatives/replacements caused by bans/reductions in certain antimicrobial compounds being available in some parts of the world.In the presence of enteric disease(s) after weaning, a deterioration in ‘gut health’ may be synonymous to the overall health of the pig, and although some direct relationships can be drawn between pig performance and efficiency and a ‘healthy' GIT, sometimes this connection is subtler and less obvious, especially in the absence of overt enteric disease(s).The factors and conditions involved in ‘gut health’ are multifactorial, complex, often poorly described and sometimes incorrectly interpreted,although it is evident that perturbations of the GIT can cause an imbalance and disturb the generalized homeostasis.In addition to any enteric diseases or conditions that might arise as a result of these disturbances, other influences will also impact such as the responses occurring in the GIT in the period immediately after weaning, any changes that might occur after a change in diet, and(or) disruptions to meal patterns and hence the flow of nutrients.Ultimately, ‘gut health’ represents the outcome of the GIT in response to its capacity and ability to respond and adapt to the insults and challenges it encounters. | John R.Pluske Diana L.Turpin Jae-Cheol Kim | 2018 | Animal Nutrition2018，，2： | 31 |
| 7 | 凡纳滨对虾养殖塘叶绿素a与水质因子的多元回归分析显示文摘2009年4-9月期间,对上海市奉贤区某凡纳滨对虾养殖场22个养殖池塘水体叶绿素a、水温、pH、溶解氧、透明度、悬浮物(SS)、总有机碳(TOC)、五日生化需氧量(BOD5)、高锰酸盐指数(CODMn)等15项水质因子进行测定。取164组测定数据,进行描述性统计,分析叶绿素a与各项因子的相关性系数。分析结果显示,与叶绿素a呈极显著线性正相关的水质因子为SS、TOC、BOD5、CODMn、TN、TP;呈显著正相关的为DO;而叶绿素a与透明度呈极显著线性负相关,与PO43--P呈显著线性负相关;与水温、pH、NO2--N、NO3--N、NH3-N则未呈现显著相关性。根据多元线性回归选择自变量的原则,选择了TOC、TN、PO34--P和TP4项水质因子,建立了叶绿素a与4项水质因子的逐步回归模型:Chl.a=-0.0545+0.00349TOC+0.0153TN-0.418PO43--P+0.276TP(r=0.7155)。利用偏回归系数检验各水质因子对叶绿素a的影响,结果表明,对叶绿素a影响从大到小依次是TP、TOC、PO34--P和TN。研究结果对进一步探讨养殖池塘生态系统的变化规律及水环境质量保护提供了依据。 | 江敏 余根鼎 戴习林 刘利平 顾德平 胡伟国 Diana James S | 2010 | 水产学报2010，34，11： | 20 |
| 8 | 报告随机对照试验的CONSORT声明修订版:说明与详述(一)显示文摘有充分的证据表明目前随机对照试验(RCT)的报告质量不尽如人意。最近的方法学调查表明,不恰当的报告及试验设计将使治疗措施的效果产生偏倚。这种系统偏差正严重损害RCT本可摒弃系统偏差的特征。RCT中的系统偏差反映出了科学性差,而科学性差会严重影响正确的伦理标准。科学家和编辑们共同制定了CONSORT(试验报告统一标准,ConsolidatedStandardsofReportingTrials,)声明以提高RCT报告质量。CONSORT声明由清单和流程图组成,作者可用来报告RCT。许多优秀期刊和重要国际性编辑组织已经采用CONSORT声明。CONSORT声明为作者提高临床试验报告质量提供指南,使得评价和解释RCT结果更方便。此文旨在增强大家对CONSORT声明的理解、应用和传播,并对每个清单项目的意义和原理进行了说明。很多项目都列出优秀报告的示例,并尽可能参考相关的经验性研究,还列出几个流程图的示例。CONSORT声明的说明和详述文件在以下网址可找到:http://gffzzff905fc352db4ba6hqw9fvf6xcc606k06.ffgz.tsg.suse.edu.cn,这是提高随机对照试验报告质量的有益资源。 | Douglas G.Altman Kenneth F.Schulz David Moher Matthias Egger Frank Davidoff Diana Elbourne Peter C.Gφtzsch Thomas Lang the CONSORT Group 刘雪梅 | 2005 | 中国循证医学杂志2005，5，9： | 19 |
| 9 | NADPH oxidases: an overview from structure to innate mmunity-associated pathologies显示文摘 | Arvind Panday Malaya K Sahoo Diana Osorio Sanjay Batra | 2015 | Cellular & Molecular Immunology2015，12，1： | 19 |
| 10 | indocyanine green-based fluorescence imaging in visceral and hepatobiliary and pancreatic surgery:State of the art and future directions显示文摘In recent years, the use of fluorescence-guided surgery(FGS) to treat benign and malignant visceral, hepatobiliary and pancreatic neoplasms has significantly increased. FGS relies on the fluorescence signal emitted by injected substances(fluorophores) after being illuminated by ad hoc laser sources to help guide the surgical procedure and provide the surgeon with real-time visualization of the fluorescent structures of interest that would be otherwise invisible. This review surveys and discusses the most common and emerging clinical applications of indocyanine green(ICG)-based fluorescence in visceral, hepatobiliary and pancreatic surgery. The analysis, findings, and discussion presented here rely on the authors' significant experience with this technique in their medical institutions, an up-to-date review of the most relevant articles published on this topic between 2014 and 2018, and lengthy discussions with key opinion leaders in the field during recent conferences and congresses. For each application, the benefits and limitations of this technique, as well as applicable future directions, are described. The imaging of fluorescence emitted by ICG is a simple, fast,relatively inexpensive, and harmless tool with numerous different applications in surgery for both neoplasms and benign pathologies of the visceral and hepatobiliary systems. The ever-increasing availability of visual systems that can utilize this tool will transform some of these applications into the standard of care in the near future. Further studies are needed to evaluate the strengths and weaknesses of each application of ICG-based fluorescence imaging in abdominal surgery. | Gian Luca Baiocchi Michele Diana Luigi Boni | 2018 | World Journal of Gastroenterology2018，24，27： | 19 |
| 11 | 高血压的时间治疗学显示文摘 | Ramón C. Hermida Diana E. Ayala Michael H. Smolensky Francesco Portaluppi 赵子彦 | 2007 | 中华高血压杂志2007，15，8： | 18 |
| 12 | Structure and Dynamics of the Isoprenoid Pathway Network显示文摘Isoprenoids 是机能上地并且植物代谢物的最多样的组迄今为止报导了的在结构上。他们能作为主要代谢物工作,参予必要植物细胞的进程,和同样第二等的代谢物,许多有实质的广告,药理学,和农业价值。Isoprenoid 结束产品在 synergistically 两个都在他们行动的大量生理的过程参予植物,例如在光合作用期间的叶绿素和类胡萝卜素,或反对地,例如 gibberellic 酸和在种子萌芽期间酸的 abscisic。这因此被期望经由 isoprenoid 的流动新陈代谢的网络紧时间地并且空间地被控制,并且这控制在全部 isoprenoid 上发生在规定并且以一种安排方式的不同层次新陈代谢的网络。在这评论,我们在跟随多样的刺激的基因表达式水平总结我们植物 isoprenoid 小径网络和它的规定的拓扑学的当前的知识。我们由讨论从植物 isoprenoid 新陈代谢出现的 agronomical 和 biotechnological 应用程序得出结论并且在植物 isoprenoid 小径网络的系统分析在未来方向上提供眼界。 | Eva Vranova Diana Coman Wilhelm Gruissem | 2012 | Molecular Plant2012，5，2： | 18 |
| 13 | 凡纳滨对虾池塘水质及对虾肌肉品质的对比分析显示文摘2010年5-9月期间,对上海奉贤区两个养殖场采取不同养殖方式的22个凡纳滨对虾养殖塘的水温(T)、总溶解盐(TDS)、溶解氧(DO)、pH、透明度(SD)、亚硝酸盐氮(NO2-N)、总氨氮(TAN)、硝酸盐氮(NO3-N)、总氮(TN)、活性磷(PO4-P)、总磷(TP)、叶绿素a(Chl.a)、五日生化需氧量(BOD5)等因子进行监测,其中1号场养殖用水为经沉淀处理的天然河水,而2号场则为添加了海水晶的河水。结果表明:试验期间水体的温度、DO、pH变化幅度不大,基本可满足凡纳滨对虾生长的条件;总体上硝酸盐氮(NO3-N)在无机氮(TIN)中所占比例最高,总氨氮(TAN)在TIN中所占比例随养殖周期的推延而增加,养殖后期NO2-N所占比例升高趋势明显;活性磷含量则逐渐下降,总磷逐渐升高;BOD5、叶绿素a的含量随时间延长而逐渐上升。测定了两个养殖场成虾的肌肉品质结果如下:1号场南美白对虾肌肉的粗蛋白和粗脂肪含量分别为16.30%和1.42%,低于2号场的18.30%和1.61%;1号场成虾氨基酸总量为23.27%,其中必需氨基酸含量为9.09%,而2号场则分别为27.52%和10.74%;在鲜味氨基酸方面,1号、2号养殖场的含量分别为8.52%和10.16%。 | 李世凯 江敏 戴习林 刘利平 胡伟国 JAMES S. DIANA | 2012 | 上海海洋大学学报2012，21，6： | 18 |
| 14 | Reducing preoperative fasting time: A trend based on evidence显示文摘Preoperative fasting is mandatory before anesthesia to reduce the risk of aspiration.However,the prescribed 6-8 h of fasting is usually prolonged to 12-16 h for various reasons.Prolonged fasting triggers a metabolic response that precipitates gluconeogenesis and increases the organic response to trauma.Various randomized trials and meta-analyses have consistently shown that is safe to reduce the preoperative fasting time with a carbohydrate-rich drink up to 2 h before surgery.Benefits related to this shorter preoperative fasting include the reduction of postoperative gastrointestinal discomfort and insulin resistance.New formulas containing amino acids such as glutamine and other peptides are being studied and are promising candidates to be used to reduce preoperative fasting time. | JoséEduardo de Aguilar-Nascimento Diana Borges Dock-Nascimento | 2010 | World Journal of Gastrointestinal Surgery2010，2，3： | 17 |
| 15 | Self-Assembly and Photocatalysis of Mesoporous TiO2 Nanocrystal Clusters显示文摘有大表面区域和提高的 photocatalytic 活动的锐钛矿 TiO2 的 Mesoporous nanocrystal 簇成功地被综合了。合成包含进亚微米簇,有硅石层的这些簇的涂层,移开器官的 ligands 并且改进簇的 crystallinity 的热处理,和暴露 mesoporous 催化剂的最后搬迁的硅石的恐水病的 TiO2 nanocrystals 自己组装。在硅石涂层的帮助下,簇不仅维持他们的小谷物尺寸而且在高温度在锻烧以后保留他们的 mesoporous 结构(与象 277 m2/g 一样高的赌注表面区域) 。蚀刻 SiO2 也导致在水里有高 dispersity 的簇。我们能识别最佳的锻烧温度生产拥有高 crystallinity 和大表面区域的 TiO2 nanocrystal 簇,因此由紫外光在照明下面在器官的分子的分解显示出优秀催化效率。与氮的方便的做在可见的光和自然日光把这些 nanocrystal 簇变换成活跃光催化剂。用 nanocrystals 形成明确的 mesoporous 簇的策略为与提高的活动和稳定性设计光催化剂答应一个万用、有用的方法。 | Qiao Zhang Ji-Bong Joo Zhenda Lu Michael Dahl Diana Q. L. Oliveira Miaomiao Ye Yadong Yin | 2011 | Nano Research2011，4，1： | 17 |
| 16 | Biological response to prosthetic debris显示文摘Joint arthroplasty had revolutionized the outcome of orthopaedic surgery. Extensive and collaborative work of many innovator surgeons had led to the development of durable bearing surfaces, yet no single material is considered absolutely perfect. Generation of wear debris from any part of the prosthesis is unavoidable. Implant loosening secondary to osteolysis is the most common mode of failure of arthroplasty. Osteolysis is the resultant of complex contribution of the generated wear debris and the mechanical instability of the prosthetic components. Roughly speaking, all orthopedic biomaterials may induce a universal biologic hostresponse to generated wear débris with little specific characteristics for each material; but some debris has been shown to be more cytotoxic than others. Prosthetic wear debris induces an extensive biological cascade of adverse cellular responses, where macrophages are the main cellular type involved in this hostile inflammatory process. Macrophages cause osteolysis indirectly by releasing numerous chemotactic inflammatory mediators, and directly by resorbing bone with their membrane microstructures. The bio-reactivity of wear particles depends on two major elements: particle characteristics(size, concentration and composition) and host characteristics. While any particle type may enhance hostile cellular reaction, cytological examination demonstrated that more than 70% of the debris burden is constituted of polyethylene particles. Comprehensive understanding of the intricate process of osteolysis is of utmost importance for future development of therapeutic modalities that may delay or prevent the disease progression. | Diana Bitar Javad Parvizi | 2015 | World Journal of Orthopedics2015，6，2： | 16 |
| 17 | Diagnostic aids for detection of oral precancerous conditions显示文摘Oral cancer has a tendency to be detected at late stage which is detrimental to the patients because of its high mortality and morbidity rates. Early detection of oral cancer is therefore important to reduce the burden of this devastating disease. In this review article, the most common oral precancerous lesions are discussed and the importance of early diagnosis is emphasized. In addition, the most common non-invasive oral cancer devices that can aid the general practitioners in early diagnosis are also discussed. | Diana V Messadi | 2013 | International Journal of Oral Science2013，5，2： | 15 |
| 18 | 硫胺素与甘草酸二铵治疗慢性乙型肝炎的临床疗效分析显示文摘观察硫胺素与甘草酸二铵治疗慢性乙型肝炎的临床疗效。在美国加州及大连分别对慢性乙型肝炎患者应用硫胺素和甘草酸二铵。甘草酸二铵组与甘草酸二铵 +硫胺素组肝功复常率两组间有显著差异 ;硫铵素组与上述两组比较肝功复常率明显降低 ,差异显著。硫铵素组连续用药 4 8周后 ,肝功复常率、血清HBVDNA、HBeAg阴转率与治疗第八周结束时各治疗组比较有显著差异。硫铵素可降低乙肝病毒含量 ,稳定肝脏内环境 。 | 李永新 高庆伟 Diana M Luan Amy E. Wallace 王英兰 | 2003 | 临床肝胆病杂志2003，19，4： | 12 |
| 19 | 应对中国隐现的人才短缺显示文摘来自麦肯锡全球研究院的研究表明,中国宠大的大学毕业生队伍中极少有入具备在服务出口行业成功工作的能力,这对目前在华的跨国公司和日渐增多的胸怀全球的中国企业将产生严重的影响。 | Diana Farrell 高安德 | 2005 | 商学院2005，，11： | 12 |
| 20 | Effectiveness of Acupuncture on Pain, Physical Function and Health-Related Quality of Life in Patients with Rheumatoid Arthritis: A Systematic Review of Quantitative Evidence显示文摘Objective: To identify and synthesize the most recent available evidence of effectiveness of acupuncture on pain, physical function and health-related quality of life(HRQoL) in patients with rheumatoid arthritis(RA). Methods: A comprehensive search of 12 Western and Chinese databases was undertaken from their inception up to end of 2016. Randomized controlled trials(RCTs), concerning patients with RA treated with needle acupuncture, written in English, Portuguese, German or Chinese were included. Primary outcomes included pain, physical function and HRQoL. Secondary outcomes included morning stiffness, functional impairment, number of tender and swollen joints and serum concentrations of inflamatory markers. Methodological quality was assessed by three independent reviewers using the standardized critical appraisal instrument from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument. Results: Twenty-two studies met the inclusion criteria. Of those, 9 studies were excluded after assessment of their methodological quality. The remaining 13 original RCTs included 974 patients. Ten of these studies published in China, showed favorable statistical significant effects of acupuncture in relieving symptoms of RA compared with controls. Conclusions: Evidence suggests that acupuncture interventions may have a positive effect in pain relief, physical function and HRQo L in RA patients. However, due to the heterogeneity and methodologic limitations of the studies included in this systematic review, evidence is not strong enough to produce a best practice guideline. | Susana Seca Diana Miranda Daniela Cardoso Bernice Nogueira Henry J.Greten Antonio Cabrita Manuel Alves Rodrigues | 2019 | Chinese Journal of Integrative Medicine2019，25，9： | 11 |
您所在的机构暂未开通此部分的功能，请联系管理员