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| 1 | Update on imaging of Peutz-Jeghers syndrome显示文摘Peutz-Jeghers syndrome(PJS) is a rare, autosomal dominant disease linked to a mutation of the STK 11 gene and is characterized by the development of benign hamartomatous polyps in the gastrointestinal tract in association with a hyperpigmentation on the lips and oral mucosa. Patients affected by PJS have an increased risk of developing gastrointestinal and extra-digestive cancer. Malignancy most commonly occurs in the smallbowel. Extra-intestinal malignancies are mostly breast cancer and gynecological tumors or, to a lesser extent, pancreatic cancer. These polyps are also at risk of acute gastrointestinal bleeding, intussusception and bowel obstruction. Recent guidelines recommend regular smallbowel surveillance to reduce these risks associated with PJS. Small-bowel surveillance allows for the detection of large polyps and the further referral of selected PJS patients for endoscopic enteroscopy or surgery. Video capsule endoscopy, double balloon pushed enteroscopy,multidetector computed tomography and magnetic resonance enteroclysis or enterography, all of which are relatively new techniques, have an important role in the management of patients suffering from PJS. This review illustrates the pathological, clinical and imaging features of small-bowel abnormalities as well as the role and performance of the most recent imaging modalities for the detection and follow-up of PJS patients. | Catherine Tomas Philippe Soyer Anthony Dohan Xavier Dray Mourad Boudiaf Christine Hoeffel | 2014 | World Journal of Gastroenterology2014，20，31： | 5 |
| 2 | Esophageal perforations显示文摘 | M. Chirica A. Champault X. Dray L. Sulpice N. Munoz-Bongrand E. Sarfati P. Cattan | 2010 | Journal of Visceral Surgery2010，，3： | 3 |
| 3 | Dual-color deep-tissue three-photon microscopy with a multiband infrared laser显示文摘Multiphoton microscopy combined with genetically encoded fluorescent indicators is a central tool in biology.Threephoton(3P)microscopy with excitation in the short-wavelength infrared(SWIR)water transparency bands at 1.3 and 1.7μm opens up new opportunities for deep-tissue imaging.However,novel strategies are needed to enable in-depth multicolor fluorescence imaging and fully develop such an imaging approach.Here,we report on a novel multiband SWIR source that simultaneously emits ultrashort pulses at 1.3 and 1.7μm that has characteristics optimized for 3P microscopy:sub-70 fs duration,1.25 MHz repetition rate,and μJ-range pulse energy.In turn,we achieve simultaneous 3P excitation of green fluorescent protein(GFP)and red fluorescent proteins(mRFP,mCherry,tdTomato)along with third-harmonic generation.We demonstrate in-depth dual-color 3P imaging in a fixed mouse brain,chick embryo spinal cord,and live adult zebrafish brain,with an improved signal-to-background ratio compared to multicolor twophoton imaging.This development opens the way towards multiparametric imaging deep within scattering tissues. | Khmaies Guesmi Lamiae Abdeladim Samuel Tozer Pierre Mahou Takuma Kumamoto Karolis Jurkus Philippe Rigaud Karine Loulier Nicolas Dray Patrick Georges Marc Hanna Jean Livet Willy Supatto Emmanuel Beaurepaire Frédéric Druon | 2018 | Light(Science & Applications)2018，7，1： | 3 |
| 4 | Transjugular intrahepatic portosystemic shunt as bridge-to-surgery in refractory gastric antral vascular ectasia显示文摘Gastric antral vascular ectasia(GAVE) may cause gastrointestinal bleeding(GIB). The treatment of GAVE relies on endoscopic approaches such as electrocoagulation(argon plasma coagulation, laser therapy, heater probe therapy, radiofrequency ablation), cryotherapy, and band ligation. In refractory cases, antrectomy may be considered. In the event of an associated cirrhosis and portal hypertension, it has been suggested that antrectomy could be an option, provided the mortality risk isn't considered too great. We report the case of a 67-year-old cirrhotic patient who presented with GAVE related GIB, unresponsive to multiple endoscopic treatments. The patient had a good liver function(model for end-stage disease 10). After a multidisciplinary meeting, a transjugular intrahepatic portosystemic shunt(TIPS) procedure was performed, in order to treat the cirrhosis associated ascites. The outcome was successful. An antrectomy was then performed, with no recurrence of GIB and no transfusion need during three months of follow up. In this case, the TIPS procedure achieved a complete ascites regression, allowing a safer surgical treatment of the GAVE-related GIB. | Aymeric Becq Violaine Ozenne Aurélie Plessier Patrice Valleur Xavier Dray | 2015 | World Journal of Gastroenterology2015，21，18： | 3 |
| 5 | Reliable gastric closure after natural orifice translumenal endoscopic surgery (NOTES) using a novel automated flexible stapling device显示文摘 | O. R. Meireles S. V. Kantsevoy L. R. Assumpcao P. Magno X. Dray S. A. Giday A. N. Kalloo E. J. Hanly M. R. Marohn | 2008 | Surgical Endoscopy2008，，7： | 2 |
| 6 | Factors Associated With Diagnosis of Obscure Gastrointestinal Bleeding by Video Capsule Enteroscopy显示文摘 | Lucie Lepileur Xavier Dray Michel Antonietti Isabelle Iwanicki–Caron Sébastien Grigioni Ulriikka Chaput Aude Di–Fiore Raied Alhameedi Philippe Marteau Philippe Ducrotté Stéphane Lecleire | 2012 | Clinical Gastroenterology and Hepatology2012，，12： | 2 |
| 7 | Carcinoid tumors of the small-bowel: Evaluation with 64-section CT-enteroclysis显示文摘 | Philippe Soyer Anthony Dohan Clarisse Eveno Xavier Dray Lounis Hamzi Christine Hoeffel Rachid Kaci Mourad Boudiaf | 2013 | European Journal of Radiology2013，，6： | 2 |
| 8 | Modulation of spinal excitability:co-operation between neurokinin and excitatory amino acide neurotransmitters 显示文摘 | URBAN I THOMPSON S W N DRAY A | 1994 | Trends Neurosci1994，17，： | 1 |
| 9 | Foreign bodies and caustic lesions 显示文摘 | Dray X Cattan P | 2013 | Best Pract Res Clin Gastroentero12013，27，5： | 1 |
| 10 | p16INK4a as a complementary marker of high grade intraepithelial lesions of the uterine cervix:experience with squamous lesions in 189 consecutive cervical biopsies显示文摘 | Dray M Russell P Dalrymple C | 2005 | Pathology2005，37，2： | 1 |
| 11 | Apelin stimulates glucose utilization in normal and obese insulin-resistant mice显示文摘 | DRAY C KNAUF C DAVIAUD D | 2008 | Cell Metab2008，8，5： | 1 |
| 12 | Cloud point extraction:an alternative to traditional liquid-liquid extraction for lanthanides(Ⅲ) separation显示文摘 | Favre-Reguillon A Draye M Lebuzit G | 2004 | Talanta2004，63，3： | 1 |
| 13 | Malnutrition in Adults with Cystic Fibrosis显示文摘 | Dray X Kanaan R Bienvenu T | 2005 | Eur J Clin Nutr2005，59，1： | 1 |
| 14 | Spatial modeling : a comprehensive framework for principal coordinate analysis of neighbor matrices ( PC- NM) 显示文摘 | Dray S Legendre P Peres - Neto P R | 2006 | Ecological Modelling2006，196，： | 1 |
| 15 | Octreotide for recurrent intestinal variceal bleeding in patients without portal hypertension显示文摘 | Dray X Vahedi K Odinot JM | 2009 | Eur J Gastroenterol Hepatol2009，21，7： | 1 |
| 16 | Tube feeding improves intestinal absorption in short bowel syndrome patients显示文摘 | Joly F Dray X Corcos O | 2009 | Gastroenterology2009，136，3： | 1 |
| 17 | Air and Fluid Leak Tests after NOTES Procedures: a Pilot Study in a Live Porcine Model 显示文摘 | Dray X Gabrielson K L Buseaglia J M | 2008 | Gastrointest Endosc2008，68，3： | 1 |
| 18 | Spatial modeling : a comprehensive framework for principal coordinate analysis of neighbor matrices (PCNM)显示文摘 | Dray S Legendre P Peres-Neto P R | 2006 | Ecological Modelling2006，196，： | 1 |
| 19 | Factors associated with diagnosis of obscure gastrointestinal bleeding by video capsule enteroscopy 显示文摘 | Lepileur L Dray X Antonietti M | 2012 | Clin Gastroenterol Hepatol2012，10，12： | 1 |
| 20 | Hydrogen Leak Test Is Minimally Invasive and Highly Specific for Assessment of the Integrity of the Luminal Closure after Natural Orifice Transluminal Endoscopic Surgery Procedures显示文摘 | Dray X Redding S K Shin E J | 2009 | Gastrointest Endose2009，69，31： | 1 |
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