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412篇 您的检索式：作者名="Fuller T"

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	题名	作者	年代	出处	被引量
1	Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations显示文摘	Thompson MC Fuller C Hogg TL Dalton J Finkelstein D Lau CC Chintagumpala M Adesina A Ashley DM KeUie SJ Taylor MD Curran T Gajjar A Gilbertson RJ	2006	中国神经肿瘤杂志2006，4，1：	17
2	Tumor Antigen Specific Activation of Primary Human T-Cells Expressing a Virally Encoded Chimeric T-Cell Receptor Specific for p185HER2显示文摘We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vectors expressing the N29γ or N29ζ receptors were constructed in pRET6. Amphotropic viral producer cells were established in the GALV-based PG13 packaging cell line. Ficoll purified human peripheral blood lymphocytes (PBL) were virally transduced using an optimized protocol incorporating activation with immobilized anti-CD3/anti-CD28 monoclonal anti- bodies, followed by viral infection in the presence of fibronectin fragment CH296. Transduced cells were co-cultured with human tumor cell lines that overexpress (SK-OV-3) or underexpress (MCF7) p185HER2 to assay for antigen specific im- mune responses. Both CM+ and CD8+ T-cells transduced with the N29γ or N29ζ chTCR demonstrated HER2-specific anti- gen responses, as determined by release of Th1 like cytokines, and cellular cytotoxicity assays. Our results support the fea- sibility of adoptive immunotherapy with genetically modified T-cells expressing a chTCR specific for p185HER2.	杨建民 Michael S FRIEDMAN Christopher M REYNOLDS Marianne T HUBEN Lee WILKE Jennifer FULLER 李桥 Zelig ESHHAR James J MULE Kevin T MCDONAGH	2004	Journal of Microbiology and Immunology2004，2，4：	5
3	In vivo anti-tumor activity of murine hematopoietic stem cells expressing a p185HER2-specific chimeric T-cell receptor gene显示文摘We have confirmed efficient anti-tumor activities of the peripheral lymphocytes transduced with a p185HER2-specific chimeric T-cell receptor gene both in murine and in human in our previous studies. To further test the feasibility of chimeric T-cell receptor in a bone marrow transplantation model, we first, made two murine tumor cell lines: MT901 and MCA-205, to express human p185HER2 by retroviral gene transduction. Murine bone marrow cells were retrovirally transduced to express the chimeric T-cell receptor and gene-modified bone marrow cells were transplanted into lethally irradiated mouse. Six months post transplantation, p185HER2-positive tumor cells:MT-901/HER2 or MCA-205/ HER2 was subcutaneously or intravenously injected to make mouse models simulating primary breast cancer or pulmonary metastasis. The in vivo anti-tumor effects were monitored by the size of the subcutaneous tumor or counting the tumor nodules in the lungs after India ink staining. The size of the subcutaneous tumor was significantly inhibited and the number of pulmonary nodules were significantly decreased in mouse recipients transplanted with chimeric T-cell receptor modified bone marrow cells compared with the control group. Our results suggest the efficient in vivo anti-tumor activities of chimeric T-cell receptor gene modified bone marrow cells.	JIAN MIN YANG MICHAEL S FRIEDMAN MARIANNE T HUBEN JENNIFER FULLER QIAO LI ALFRED E CHANG JAMES J MULE KEVIN T MCDONAGH	2006	Journal of Microbiology and Immunology2006，4，2：	3
4	Lithium insertion in high capacity carbonaceous materials显示文摘	ZHENG T LIU Y FULLER E W	1995	J Electrochem Soc1995，142，8：	2
5	Control of mitochondrial morphology by a human mitofusin显示文摘	SANTEL A FULLER M T	2001	J Cell Sci2001，114，5：	1
6	Proposal: the leopard cat ( Felisben- galensis) in China: ecology and management for sustainable utiliza- tion显示文摘	JOHNSON K A FULLER T K	2004	J Forestry Res2004，15，4：	1
7	Newly codified glial neop asms of the 2007 WHO classification of tumours of the central nervous system: angiocentric glioma, pilomyxoid astrocyto- ma and pituicytoma 显示文摘	Brat D J Scheithauer B W Fuller G N Tihan T	2007	Brain Pathol2007，17，3：	1
8	Modeling of galvanostatic charge and discharge of the lithium/polymer/insertion cell显示文摘	Doyle M Fuller T F Newman J	1993	Journal of the Electrochemical Society1993，140，6：	1
9	Pharmacokinetics of quetiapine in elderly patients with selected psychotic disorders显示文摘	Jaskiw G E Thyrum P T Fuller M A	2004	Clin Pharmacokinet2004，43，14：	1
10	A methanol sensor for portable direct methanol fuel cells显示文摘	Barton S A C Murach B L Fuller T F	1998	Journal of the electrochemical society1998，145，11：	1
11	Forest management effects on carabid beetle communities in coniferous and broadleaved forests: implications for conservation显示文摘	Fuller R J Oliver T H Leather H R	2008	Insect Conservation and Diversity2008，1，：	1
12	A critical review of thermal issues in lithium-ion batteries 显示文摘	BANDHAUER T M GARIMELLA S FULLER T F	2011	Journal of The Electrochemical Society2011，158，3：	1
13	Water and thermal management in solid- polymer-electrolyte fuel cells显示文摘	FULLER T F NEWMAN J	1993	Journal of Electro-chemical Society1993，140，1：	1
14	Water and thermal management in solid-polymer-electrolyte fuel cells 显示文摘	FULLER T F NEWMAN J	1993	J Electrochem Soc1993，140，：	1
15	Water and thermal management in solid-polymer-electrolyte fuel cells 显示文摘	Fuller T F Newman J	1993	J Electrochem Soc1993，140，1：	1
16	Resorption of bone by isolated rabbit osteoclasts 显示文摘	Chamber T J Revell P A Fuller K	1984	Cell Sci1984，66，：	1
17	Model-based analysis and classification of driver distraction under secondary tasks显示文摘	ERSAL T FULLER H J A TSIMHONI O	2010	Ieee Transactions on Intelligent Transportation Systems2010，11，3：	1
18	The room temperature ionic liquid 1-ethyl-3-methyl imidazolium terefluoroborate: electrochemical couples and physical properties显示文摘	Carlin R T Oster young R A	1997	J Eleetroehem Soc1997，144，11：	1
19	Osteoclast activation: potent inhibition by the bisphosphonate alendronate through a nonresorptive mechanism显示文摘	Owens J M Fuller K Chambers T J	1997	J Cell Physiol1997，172，2：	1
20	Assessing estimators of snow leopard abundance显示文摘	MCCARTHY K P FULLER T K MA M	2008	The Journal of Wildlife Management2008，72，8：	1

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