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| 1 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 12 |
| 2 | Human enamel thickness and ENAM polymorphism显示文摘The tooth enamel development gene, enamelin(ENAM), showed evidence of positive selection during a genome-wide scan of human and primate DNA for signs of adaptive evolution. The current study examined the hypothesis that a single-nucleotide polymorphism(SNP) C14625T(rs7671281) in the ENAM gene identified in the genome-wide scan is associated with a change in enamel phenotype. African Americans were selected as the target population, as they have been reported to have a target SNP frequency of approximately 50%, whereas non-Africans are predicted to have a 96% SNP frequency. Digital radiographs and DNA samples from 244 teeth in 133 subjects were analysed, and enamel thickness was assessed in relation to SNP status,controlling for age, sex, tooth number and crown length. Crown length was found to increase with molar number, and females were found to have thicker enamel. Teeth with larger crowns also had thicker enamel, and older subjects had thinner enamel.Linear regression and generalized estimating equations were used to investigate the relationship between enamel thickness of the mandibular molars and ENAM SNP status; enamel in subjects with the derived allele was significantly thinner(P = 0.040)when the results were controlled for sex, age, tooth number and crown length. The derived allele demonstrated a recessive effect on the phenotype. The data indicate that thinner dental enamel is associated with the derived ENAM genotype. This is the first direct evidence of a dental gene implicated in human adaptive evolution as having a phenotypic effect on an oral structure. | Diane M Daubert Joanna L Kelley Yuriy G Udod Carolina Habor Chris G Kleist Ilona K Furman Igor N Tikonov Willie J Swanson Frank A Roberts | 2016 | International Journal of Oral Science2016,8,2: | 2 |
| 3 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 1 |
| 4 | The Determinants of National Innovative Capacity显示文摘 | FURMAN J L PORTER M E STERN S | 2002 | Research Policy2002,31,8: | 1 |
| 5 | Management of colorectal carcinoma in children and young adults显示文摘 | Goldberg J Furman W L | | 0,,2: | 1 |
| 6 | Dynamics of entanglement in a one-dimensional Ising chain显示文摘 | Furman G B Meerovich V M Sokolovsky V L | 2008 | Phys Rev A2008,77,06: | 1 |
| 7 | The Determinants of National Innovative Capacity显示文摘 | FURMAN JEFFERY L MICHAEL E P SCOTT STERN | 2002 | Research Policy2002,31,6: | 1 |
| 8 | The determinants of national innovative capacity 显示文摘 | Furman J L Porter M E Stern S | 2002 | Research Policy2002,31,6: | 1 |
| 9 | The determinants of nati- onal innovative capacity显示文摘 | Furman J L Porter M E Stem S | 2002 | Research Policy2002,31,6: | 1 |
| 10 | The Determinants of Na- tional Innovative Capacity 显示文摘 | Furman J L Porter M E Stem S | 2002 | Research Policy2002,31,6: | 1 |
| 11 | 2010 Mechanism of base activation of persulfate 显示文摘 | Furman O S Teel A L Watts R J | 2010 | Environmental Science & Technology2010,44,: | 1 |
| 12 | The determinants of national innovative capacity显示文摘 | Jeffrey L Furman Michael E Porter Scott Stern | 2002 | Research Policy2002,,6: | 1 |
| 13 | The determinants of national innovative capacity显示文摘 | FURMAN J L PORTER M E STERN S | 2002 | Research Policy2002,31,: | 1 |
| 14 | Catching Up or Standing Still? Na- tional Innovative Productivity among 'Follower' Countries, 1978-1999 显示文摘 | Furman J L Hayes R | 2004 | Research Policy2004,33,9: | 1 |
| 15 | The Determinants of National Inno- vative Capacity显示文摘 | Furman J L Porter M E Stern S | 2002 | Research Policy2002,31,6: | 1 |
| 16 | Epidemiology and management options for colorectal cancer in adolescent 显示文摘 | Saab R Furman W L | 2008 | Paediatr Drugs2008,10,3: | 1 |
| 17 | Mechanism of base activation of persulfate显示文摘 | FURMAN O S TEEL A L WATTS R J | 2010 | Environmental Science&Technology2010,44,16: | 1 |
| 18 | The determinants of national innovative capacity显示文摘 | Furman J L Porter M E Stern S | 2002 | Research Policy2002,31,: | 1 |
| 19 | Academic collaboration and organi- zational innovation: The development of research capabilities in the US pharmaceutical industry, 1927-1946 显示文摘 | FURMAN J L MACGARVIE M | 2009 | Industrial and Cor- porate Change2009,18,5: | 1 |
| 20 | The determi- nants of national innovative capacity 显示文摘 | FURMAN J L PORTER M E STERN S | 2002 | Research Policy2002,31,6: | 1 |