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| 1 | 在心血管的疾病的先进 glycation 结束产品的角色显示文摘 Advanced glycation end products(AGEs) are produced through the non enzymatic glycation and oxidation of proteins,lipids and nucleic acids.Enhanced formation of AGEs occurs particularly in conditions associated with hyperglycaemia such as diabetes mellitus(DM).AGEs are believed to have a key role in the development and progression of cardiovascular disease in patients with DM through the modif ication of the structure,function and mechanical properties of tissues through crosslinking intracellular as well as extracellular matrix proteins and through modulating cellular processes through binding to cell surface receptors [receptor for AGEs(RAGE)].A number of studies have shown a correlation between serum AGE levels and the development and severity of heart failure(HF).Moreover,some studies have suggested that therapies targeted against AGEs may have therapeutic potential in patients with HF.The purpose of this review is to discuss the role of AGEs in cardiovascular disease and in particular in heart failure,focussing on both cellular mechanisms of action as well as highlighting how targeting AGEs may represent a novel therapeutic strategy in the treatment of HF. | Zeinab Hegab Stephen Gibbons Ludwig Neyses Mamas A Mamas | 2012 | World Journal of Cardiology2012，4，4： | 58 |
| 2 | The Partial Hydrolysis of Dialkyltin Dihalides显示文摘 | Gibbons A J Sawyer A K Ross A | 1961 | J Org Chem1961，26，： | 1 |
| 3 | Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells显示文摘 | Hsieh FH Sharma P Gibbons A | 2005 | Proc Natl Acad Sci USA2005，102，14： | 1 |
| 4 | Refocusing the agendaon cardiovascular guidelines: an announcement from the National Heart, Lung, and Blood Institute显示文摘 | Gibbons G H Shurin S B Mensah G A | 2013 | Circulatinn2013，128，15： | 1 |
| 5 | Relativistically correct hole-boring and ion acceleration by circularly polarized laser pulses显示文摘 | A P L Robinson P Gibbon M Zepf S Kar R G Evans C Bellei | 2009 | Plasma Physics and Controlled Fusion2009，，2： | 1 |
| 6 | The combined effects of zafirlukast, prednisone, and inhaled budesonide on IL-13 and IFN-gamma secretion显示文摘 | Gibbons FK Israel E Deykin A | 2005 | J Clin Immunol2005，25，5： | 1 |
| 7 | Modelling uncertainty ingreenhouse gas emissions from UK agriculture at the farmlevel显示文摘 | Gibbons J M Ramsden S J Blake A | 2006 | Agriculture Ecosystems and Environment2006，112，4： | 1 |
| 8 | In China,a handier Homo erectus显示文摘 | | 1999 | Sciences1999，279，： | 1 |
| 9 | Engineering phosphors for field emission displays显示文摘 | Vecht A Gibbons C Davies D | 1999 | J Vac Sci Technol B1999，17，： | 1 |
| 10 | Effective university-industry interaction:a multi-case evaluation of collaborative R&D projects显示文摘 | Barnes T Pashby I Gibbons A | | 0，，03： | 1 |
| 11 | Adsorption of arsenic from a Nova Scotia groundwater onto water treatment residual solids显示文摘 | Gibbons M K Gagnon G A | 2010 | Water Res2010，44，19： | 1 |
| 12 | Social Cognition in Frontotemporal Dementia and Huntington's Disease 显示文摘 | Snowden J S Gibbons Z C Blackshaw A | 2003 | Neuropsychologia2003，41，： | 1 |
| 13 | Y chromosome shows that Adam Was Africa显示文摘 | Gibbons A | 1997 | Science1997，278，5339： | 1 |
| 14 | Chinese stone tools reveal high-tech Homo erectus显示文摘 | | 2000 | Science2000，287，： | 1 |
| 15 | Effeets of lowdose aspirin on restenosis after coronary angioplasty显示文摘 | Taylor R R Gibbons F A Cope G D | 1991 | Am J Cardiol1991，68，9： | 1 |
| 16 | Transmission beyond the dispersion limit using a negative chirp electro absorption modulator 显示文摘 | Fells J A J Gibbon M A White I H | 1994 | Electronics Letters1994，30，14： | 1 |
| 17 | Production of proton beams with narrow-hand energy spectra from laser-irradiated ultrathin foils显示文摘 | Robinson A P L Gibbon P | 2007 | Phys Rev E2007，75，01： | 1 |
| 18 | Y chromosome shows that Adam Was African显示文摘 | Gibbons A | 1997 | Science1997，278，5339： | 1 |
| 19 | 显示文摘 | Stroud R M Viano A M Gibbons P C | 1996 | Appl Phys Lett1996，29，： | 1 |
| 20 | Efficiency of sperm-mediated gene transfer in the ovine by laparoscopic insemination,in vitro fertilization and ICSI显示文摘 | Pereyra-Bonnet F Gibbons A Cueto M | 2011 | J Reprod Dev2011，57，2： | 1 |
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