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102篇 您的检索式:作者名="GOSS J R"
    题名 作者 年代 出处 被引量
1Failure of P-selectin blockade alone to protect the liver from ischemia-reperfusion injury in the isolated blood-perfused rat liver显示文摘AIM:To determine if blockade of P-selectin in the isolated blood-perfused cold ex vivo rat liver model protects the liver from ischemia-reperfusion injury. METHODS:The effect of P-selectin blockade was assessed by employing an isolated blood-perfused cold ex vivo rat liver with or without P-selectin antibody treatment before and after 6 h of cold storage in University of Wisconsin solution. RESULTS:In our isolated blood-perfused rat liver model,pre-treatment with P-selectin antibody failed to protect the liver from ischemia-reperfusion injury,as judged by the elevated aspartate aminotransferase activity. In addition,P-selectin antibody treatment did not significantly reduced hepatic polymorphonuclear leukocyte accumulation after 120 min of perfusion. Histological evaluation of liver sections obtained at 120 min of perfusion showed significant oncotic necrosis in liver sections of both ischemic control and P-selectin antibody-treated groups. However,total bile production after 120 min of perfusion was signifi cantly greater in P-selectin antibody-treated livers,compared to control livers. No signifi cant difference in P-selectin and ICAM-1 mRNAs and proteins,GSH,GSSG,and nuclear NF-κB was found between control and P-selectin antibody-treated livers. CONCLUSION:In conclusion,we have shown that blockade of P-selectin alone failed to reduced polymorphonuclear leukocyte accumulation in the liver and protect hepatocytes from ischemia-reperfusion injury in the isolated blood-perfused cold-ex vivo rat liver model.Samuel Wyllie Neal R Barshes Saul J Karpen John A Goss 2008World Journal of Gastroenterology2008,14,44:4
2Threat Perception in Product Harm Crises:Do Older Consumers Feel More Vulnerable?显示文摘Silvera D H Meyer T Laufer D Goss R J Arsena A R 2010Advances in Consumer Research2010,37,:1
3Orthotopic liver transplantation for primary sclerosing chlolangitis:a 12-year single experience显示文摘Goss J A Shackleton C R Farmer D G 1997Ann Surg1997,225,:1
4What drives health spending in theNorthern Territory显示文摘Zhao Y J Goss J Malyon R 2010Economic Papers2010,29,3:1
5Trinexapac-ethyl arm ni- trogen effects on creeping bentgrass grown under reduced light conditions 显示文摘Goss R M Baird J H Kelm S L 2002Crop Science2002,42,2:1
6A new species-specific nuclear DNA marker for identification of hybrids between Atlantic salmon and brown Trout 显示文摘Goss R Nilsson J Schmitz M 1996Journal of Fish Biology1996,49,:1
7Addressing the difficulties in using inductive methods to evaluating human body composition显示文摘Peyton A J Mackin R Goss D 2003Biometrie Humaine at Anthropologie2003,21,:1
8A novel fluorinated eryth- romycin antibiotic 显示文摘GOSS R J M HONG H 2005Chem Commun2005,,31:1
9Antinociceptive effect of a genomic herps simpex virus-based vector expressing human proenkephalin in rat dorsal root ganglion显示文摘Goss J R Mata M Goin W F 2001Gene Therapy2001,8,7:1
10Seasonal changes in the response of oyster catchers Haematopus ostralegusto human disturbance 显示文摘STILLMAN R A GOSS - CUSTARD J D 2002Journal of Avian Biology2002,33,:1
11Hypothermia attenuates the normal increase in interleukin-1β RNA and nerve growth factor following traumatic brain injury in the rat显示文摘Goss J R Styren S D Miller P D 1995J Neurotrauma1995,12,:1
12Theory of Li in ZnO:A limitation for Li-based p-type doping显示文摘Wardle M G Goss J P Briddon P R 2005Phys Rev B2005,71,15:1
13Predicting the impacts of disturbance on shore bird mortality using a behavior based model 显示文摘West A D Goss - Custard J D StiUman R A 2002Biological Conservation2002,106,3:1
14Losses of nitrate-N in water draining from uoder autunm-sewn crops established by direct drilling or moldboard ploughing显示文摘Goss M J K R Howse PW lane 1993Journal of Soil Science1993,44,1:1
15Effect of soil management productice on soil physical conditions affecting root growth显示文摘Ehlers W Goss M J Boone F R 1984Journal of Agricultural Engineering Research1984,30,:1
16The saponins-polar isoprenoids with important and diverse biological activities 显示文摘Osboum A Goss R J Field R A 2011Nat Prod Rep2011,28,7:1
17Carrying ca pacity in overwintering migratory birds显示文摘GOSS C J D STILLMAN R A WEST A D 2002Biological Conser- vation2002,105,:1
18Effect of soil management production on soil physical conditions affecting root growth显示文摘Goss M J Ehlers W Boone F R 1984J Agric Eng Res1984,30,:1
19Herpes vector-mediated expression of proenkephalin reduces bone cancer pain显示文摘Goss J R Harley C F Mata M 2002Ann Neurol2002,52,2:1
20Trinexapac-erhyl and ni trogen effects reeping bentgrass grown under reduced light conditions显示文摘Goss R M Baird J H Keim S L etal 2002Crop Science2002,42,:1
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