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272篇 您的检索式:作者名="Galipeau"
    题名 作者 年代 出处 被引量
1Plasminogen kringle 5-engineered glioma cells block migration of tumor- associated macrophages and suppress tumor vascularization and progres- sion.显示文摘Perri SR Nalbantoglu J Annabi B Koty Z Lejeune L Francois M Di Falco MR Beliveau R Galipeau J 2005中国神经肿瘤杂志2005,3,3:8
2Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease显示文摘Utilization of mesenchymal stromal cells(MSCs) for the treatment of Crohn's disease and ulcerative colitis is of translational interest.Safety of MSC therapy has been well demonstrated in early phase clinical trials but efficacy in randomized clinical trials needs to be demonstrated.Understanding MSC mechanisms of action to reduce gut injury and inflammation is necessary to improve current ongoing and future clinical trials.However, two major hurdles impede the direct translation of data derived from animal experiments to the clinical situation:(1) limitations of the currently available animal models of colitis that reflect human inflammatory bowel diseases(IBD).The etiology and progression of human IBD are multifactorial and hence a challenge to mimic in animal models; and(2) Species specific differences in the functionality of MSCs derived from mice versus humans.MSCs derived from mice and humans are not identical in their mechanisms of action in suppressing inflammation.Thus, preclinical animal studies with murine derived MSCs cannot be considered as an exact replica of human MSC based clinical trials.In the present review, we discuss the therapeutic properties of MSCs in preclinical and clinical studies of IBD.We also discuss the challenges and approaches of using appropriate animal models of colitis, not only to study putative MSC therapeutic efficacy and their mechanisms of action, but also the suitability of translating findings derived from such studies to the clinic.Raghavan Chinnadurai Spencer Ng Vijayakumar Velu Jacques Galipeau 2015World Journal of Gastroenterology2015,21,16:6
3Predictors of progression in Barrett’s esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression显示文摘Brian J Reid Laura J Prevo Patricia C Galipeau Carissa A Sanchez Gary Longton Douglas S Levine Patricia L Blount Peter S Rabinovitch 2001The American Journal of Gastroenterology2001,,10:2
4Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages 显示文摘Wang JS Shum-Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
5Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages显示文摘Wang JS Shum-Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
6Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages显示文摘Wang JS Shum-Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,:1
7Marrow stromal cells for cellar cardiomyoplasty:feasibility and potential clinical advantages显示文摘Wang JS Tim DS Galipeau J 2000Thorac Cardiovasc Surg2000,120,8:1
8A study of low-cost sensors for measuring low relative humidity 显示文摘Story P R Galipeau D W Mileham R D 1995Sensors andActuatorsB: Chemical1995,25,13:1
9Marrow stromal cells for cellular cardiomyoplasty: Feasibility and potential clinical advantages显示文摘 Shum - Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
10Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells显示文摘Allay J A Galipeau J Blakley R L 1998Stem Cells1998,16,1:1
11Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages显示文摘Wang JS Shum-Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
12Marrow stromal cells for cellular cardiomvoplasty: feasibility and potential clinical advantages 显示文摘Wang JS Shum-Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
13p53-mutant clones and field effects in barrett's esophagus1显示文摘Laura J Prevo Carissa A Sanchez Patricia C Galipeau 1999Cancer Research1999,59,19:1
14Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages 显示文摘Wang JS Shum-Tim Galipeau J 2000J Thorac Cardiovasc Surg2000,120,:1
15Marrow stromal cells for cellular cardiom yoplasty, feasibility and potential clinical advantages显示文摘Wang JS Shum Tim D Galipeau J 2000J Thorac Cardiovase Surg2000,120,5:1
16Marrow mesenchymal stem cells for celludar cardiomyoplasty:feasibility and potential clinical advantages显示文摘Wang JS Shum TD Galipeau J 2000Thorac Cardiovasc Surg2000,120,:1
17Marrow stromal cells for cellular cardiomyoplasty: feasibility and potential clinical advantages显示文摘Wang JS Shurn Tim D Galipeau J 0,,:1
18Marrow stromal cells for celluar cardiomyoplasty: feasibility and potential clinical advantages显示文摘Wang JS hum- Tim D Galipeau J 2000J Thorac Cardiovasc Surg2000,120,5:1
19Vesicular atomatitis virus G pseudotyped retrovector mediates effective in vivo suicide gene delivery in experimental brain cancer显示文摘Galipeau J Li H Paquim A 1999Cancer Res1999,59,10:1
20Vesicular stomatitis virus G pseudotyped retrovector mediates effective in vivo suicide gene delivery in experimental brain cancer 显示文摘Galipeau J Li H Paquin A 1999Cancer Res1999,59,10:1
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