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| 1 | 前庭康复网络干预对老年慢性头晕患者的效果:一项英国社区医疗机构开展的随机对照试验显示文摘目的前庭康复治疗对由前庭功能障碍所致的眩晕来说比较有效,但迄今为止这种康复治疗的开展还较少。本研究旨在探讨前庭康复网络干预项目在社区老年慢性头晕患者中的效果。方法本项为单中心、单盲的随机对照试验,在英格兰南部54家社区医疗机构开展。研究对象为来自这些机构的年龄≥50岁、患有眩晕并头部运动眩晕加重的患者。患者被随机分为干预组和普通治疗组。干预组给予前庭康复网络干预[平衡训练(患者通过网络学习前庭康复训练及认知行为管理策略),详细内容见http://gffzz647ebb38d6614268suxu6ouxwkk5969of.ffgz.tsg.suse.edu.cn],普通治疗组给予普通全科治疗。在干预前、干预3个月及6个月后,采用简明眩晕症状量表(VSS-SF)对患者的眩晕程度进行调查。干预效果的主要评估指标为干预6个月后的VSS-SF分数。结果共纳入296例患者,其中66%为女性,中位年龄为67岁。250例(84%)患者在干预3个月后完成了VSS-SF测评,230例(78%)患者在干预6个月后完成了VSS-SF测评。干预3个月后,干预组VSS-SF分数比普通治疗组低2.75分[95%CI(1.39,4.12),P<0.001];干预组眩晕残障程度分数比普通治疗组低6.15分[95%CI(2.81,9.49),P<0.001]。干预6个月后,干预组VSS-SF分数比普通治疗组低2.26分[95%CI(0.39,4.12),P=0.020];干预组眩晕残障程度分数比普通治疗组低5.58分[95%CI(1.19,10.0),P=0.010]。结论在没有临床支持的情况下,前庭康复网络干预可使社区老年慢性头晕患者眩晕及眩晕残障程度有所降低。这种康复治疗可在社区医疗机构中广泛应用。 | GERAGHTY A W A ESSERY R KIRBY S 本刊编辑部 | 2017 | 中国全科医学2017,20,28: | 10 |
| 2 | A second lineage of mammalian major histocompatibility complex class I genes 显示文摘 | Bahram S Bresnahan M Geraghty DE | 1994 | Proe Natl Acad Sci USA1994,91,: | 1 |
| 3 | CT-guided transthoracic needle aspiration biopsy of pulmonary nodules:needle size and pneumothorax rate显示文摘 | Geraghty P R Kee S T McFarlane G et a1 | 2003 | Radiology2003,229,2: | 1 |
| 4 | 前庭康复网络干预项目对社区老年眩晕患者的效果:随机对照试验研究显示文摘目的前庭康复是治疗前庭功能障碍所致眩晕的有效方法,但相关研究较少。本研究的目的是确定一个有效的前庭康复网络干预项目,为社区老年眩晕患者提供初级保健。方法本研究为单中心单盲随机对照试验,选取英国南部年龄50岁以上的社区老年眩晕患者,分为两组,一组采用前庭康复网络干预项目(干预组),一组采用常规初级护理(对照组)。干预组通过访问一个基于互联网的自动化的程序来教授前庭康复训练,并提出认知行为管理策略。基线、3个月时、6个月时采用眩晕症状量表简表(VSS-SF)检测眩晕及眩晕相关残疾情况。结果共纳入296例患者,其中女195例(66%),平均年龄67岁。250例(84%)患者3个月时完成VSS-SF检测,230例(78%)患者6个月时完成VSS-SF检测。与对照组比较,干预组3个月时与基线VSS-SF眩晕减轻,差异有统计学意义[差值2.75分,95%CI(1.39,4.12),P<0.001]和干预组6个月时与基线VSS-SF眩晕减轻,差异有统计学意义[差值2.26分,95%CI(0.39,4.12),P=0.02]。与对照组比较,干预组3个月时与基线眩晕相关残疾减轻,差异有统计学意义[差值6.15分,95%CI(2.81,9.49),P<0.001]和干预组6个月时与基线眩晕相关残疾减轻,差异有统计学意义[差值5.58分,95%CI(1.19,10.00),P=0.01]。结论前庭康复网络干预项目可以减轻社区老年眩晕患者眩晕及眩晕相关残疾,在社区环境中有广泛的应用前景。 | GERAGHTY A W A ESSERY R KIRBY S 本刊编辑部 | 2017 | 中国全科医学2017,20,20: | 1 |
| 5 | Corneal optical aberrations and retinal image quality in palients in whom monofocalintraocular lenses were implanted显示文摘 | Guirao A Redondo M Geraghty E Piers P Norrby S Artal P | 2002 | Arch Ophlhalmol2002,120,9: | 1 |
| 6 | A second lineage of mammalian major histocompatibility complex class I genes显示文摘 | Bahram S Bresnahan M Geraghty DE | | 0,,: | 1 |
| 7 | A second lineage of mammalian major histoeompatibility complex class I genes显示文摘 | Bahram S Bresnahan M Geraghty DE | 1994 | Proc Nail Aead Sei USA1994,91,14: | 1 |
| 8 | Optical add-drop multiplexers based on the antisymmetric waveguide Bragg grating 显示文摘 | CASTRO J M GERAGHTY D F HONKANEN S | 2006 | Applied Optics2006,45,6: | 1 |
| 9 | A second lineage of mammalian major histocompatibility complex class I genes 显示文摘 | Bahrain S Bresnahan M Geraghty DE | 1994 | Proc Natl Acad Sci USA1994,91,14: | 1 |
| 10 | A second lineage of mammalian major histocompatibility complex class Ⅰ genes显示文摘 | Bahram S Bresnahan M Geraghty DE | 1994 | Proc Natl Acad Sci USA1994,91,14: | 1 |
| 11 | Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1,EGF,PMA and AICAR显示文摘 | Geraghty KM Chen S Harthill JE Ibrahim AF Toth R Morrice NA | 2007 | Biochem J2007,407,2: | 1 |
| 12 | Complete sequence and gene map of a human major histocompatibility comlex 显示文摘 | Beck S Geraghty D Inoko H | 1999 | Nature1999,401,28: | 1 |
| 13 | Results of secondary prophylaxis in children with severe hemophilia显示文摘 | Manco Johnson M J Nuss R Geraghty S | | 0,,2: | 1 |
| 14 | The killer cell immunoglobulin-like receptor ( KIR ) genomic region : gene-order, haplotypes and allelic polymorphism 显示文摘 | Hsn KC Chida S Geraghty DE | 2002 | Immunol Rev2002,190,: | 1 |
| 15 | 显示文摘 | Bahram S Bresnahan M Geraghty DE | 1994 | Proc Natl Acad Sci USA1994,91,13: | 1 |
| 16 | A second lineage of mammalian major histocompatibility complex class Ⅰ genes显示文摘 | Bahrain S Bresnahan M Geraghty D E | 1994 | Proc Natl Acad Sci USA1994,91,14: | 1 |
| 17 | Evaluation of resident communication skills and professionalism:a matter of per- spective? 显示文摘 | Brinkman W B Geraghty S R Lanphear B P | 2006 | Pediatrics2006,118,4: | 1 |
| 18 | When TCP breaks delay-and disruption-tolerant networking显示文摘 | Farrell S Cahill V Geraghty D | | 0,,04: | 1 |
| 19 | A second lineage of mammalian major histocompatibility complex class I genes显示文摘 | BAHRAM S BRESNAHAN M GERAGHTY D E | 1994 | Proc Natl Acad Sci U S A1994,91,14: | 1 |
| 20 | A second lineage of mammalian major histocompatibility complex class Ⅰ genes显示文摘 | BAHRAM S BRESNAHAN M GERAGHTY D E | 1994 | Proc Natl Acad Sci USA1994,91,14: | 1 |