|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 2 | Validation of an immunoperoxidase monolayer assay for total anti-Vac- cinia virus antibody titration 显示文摘 | Gerber P F Matos A C Guedes M I | 2012 | J Vet Diagn Invest2012，24，2： | 1 |
| 3 | Con-trols of heavy minerals and grain size in a holocene regressivebarrier(Ilha Comprida,southeastern Brazil)显示文摘 | Guedes C C F Giannini P C F Nascimento D R Jr | 2011 | Journal ofSouth American Earth Sciences2011，31，1： | 1 |
| 4 | Nucleation and crystal growth in commercial LAS compositions显示文摘 | Guedes M Ferro A C Ferreira J M F | 2001 | Journal of the E(ur)opean Ceramic Society2001，，21： | 1 |
| 5 | Adances and perspectives in using microalgae to produce biodiesel显示文摘 | AMANO M HELENA GUEDES CATAEINA MALCATA XAVIER F | 2011 | Applied Energy2011，88，： | 1 |
| 6 | Nucleation and Crystal Growth in Commercial LAS Composition显示文摘 | Guedes M Ferro A C Ferreira J M F | 2001 | Journal of the European Ceramic Society2001，21，： | 1 |
| 7 | Microalgae as sources of high added-value eompounds--a brief review of recent work显示文摘 | Guedes A C Amaro H M Malcata F X | 2011 | Biotechnology Progress2011，27，3： | 1 |
| 8 | Study of the aroma compounds of rose apple (Syzygium jambos Alston) fruit from Brazil显示文摘 | Guedes C M Pinto A B Moreira R F A | 2004 | Eur Food Res Technol2004，219，： | 1 |
| 9 | The influence of starch gelatinization on the rheological,thermal,and morphological properties of poly(?-caprolactone)with corn starch blends显示文摘 | Rosa D S Guedes C G F Pedroso A G | 2004 | Materials Science and Engineering:C2004，24，5： | 1 |
| 10 | Fenton oxidation of cork cooking wastewateroverall kinetic analysis显示文摘 | Anabela M F Guedes M Luis M P | 2003 | Water Research2003，37，： | 1 |
| 11 | New Copper(Ⅱ)Dimer with 3-(2-Hydroxy-4-nitrophenylhydrazo)pentane-2,4-dione and Its Catalytic Activity in Cyclohexane and Benzyl Alcohol Oxidations 显示文摘 | Mahmudov K T Kopylovich M N Guedes da Silva M F C | 2010 | J Mol Catal A:Chem2010，318，12： | 1 |
| 12 | Study of the aroma compounds of rose apple (Syzygium jambos Alston) fruit from Brazil 显示文摘 | GUEDES C M PINTO A B MOREIRA R F A | 2004 | Eur Food Res and Technol2004，219，5： | 1 |
| 13 | The influence of starch gelatinization on the rheological,thermal,and morphological properties of poly (ε-caproolactone) with corn starch blends 显示文摘 | Roas D S Guedes C G F Pedroso A G | 2004 | Material Science and Engineering2004，24，： | 1 |
| 14 | Fenton oxidation of cork cooking wastewater-overall kinetic analysis 显示文摘 | Anabela M F M Guedes Luis M P Madeira Rui A R Boaventura | 2003 | Water Research2003，37，13： | 1 |
| 15 | Advances and perspectives in using microalgae to produce biodiesel显示文摘 | Amaro H M Guedes A C Malcata F X | | 0，，： | 1 |
| 16 | Di- and Tri-organotin ( 1V ) Complexes of Arylhydrazones of Methylene Active Compounds and Their Antiproliferative Activity显示文摘 | Mahmudov K T Guedes M F C Kopylovich M N | 2014 | J Organomet Chem2014，761，： | 1 |
| 17 | Advances and perspectives in using microalgae to produce biodiesel显示文摘 | AMARO H M GUEDES A C MALCATA F X | 2011 | Appl Energ2011，88，10： | 1 |
| 18 | Assessment of a phosporus fractionation method for soils: problems for further investigation 显示文摘 | Potter R L Jordan C F Guedes R M | 1991 | Agriculture Ecosystems and Environment1991，34，： | 1 |
| 19 | Automated separation and preconcentration of copper(Ⅱ) from natural waters using a column treatment显示文摘 | Guedes da Mota M M Rmer F G Griepink B | 1977 | Fresenius'' Journal of Analytical Chemistry1977，287，1： | 1 |
| 20 | Fenton oxidation of cork cooking wastewater-Overall kinetic analysis显示文摘 | Anabela M F Guedes M Luis M P | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员