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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 3 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 4 | The Integrator complex controls the termination of transcription at diverse classes of gene targets显示文摘包含 INTS3 和 NABP1 或 NABP2 的建筑群开始在 DNA 损坏回答被描绘,但是他们的生物化学的功能仍然保持未知。用亲密关系纯化和 HIV 集成定序目标(HIT-Seq ) ,我们发现这些建筑群是综合者建筑群的部分,它绑 RNA 聚合酶 II 并且调整特定的目标基因。综合者作为他们在亲密地被结合的机制处理到他们的成熟形式的部分劈开 snRNAs 抄写结束。然而, HIT-Seq 表明那个综合者也绑在 3 ′以 polyadenylated 抄本复制依赖者 histones 和倡导者结束基因的近似区域。综合者子单元的弄空导致抄写结束失败, histone mRNA 处理的混乱,和 snRNAs 和 histone mRNAs 的 polyadenylation。而且,倡导者综合者的近似绑定否定地通常调整其抄本是的基因的表示 polyadenylated。到所有三个基因类的综合者招募是 DSIF 依赖的,建议那个综合者作为在 DSIF 依赖的 RNA 聚合酶 II 的结束建筑群工作暂停地点。 | Jeffrey R Skaar Andrea L Ferris Xiaolin Wu Anita Saraf Kum Kum Khanna Laurence Florens Michael P Washburn Stephen H Hughes Michele Pagano | 2015 | Cell Research2015，25，3： | 2 |
| 5 | Global prevalence of dementia: a Delphi consensus study显示文摘 | Cleusa P Ferri Martin Prince Carol Brayne Henry Brodaty Laura Fratiglioni Mary Ganguli Kathleen Hall Kazuo Hasegawa Hugh Hendrie Yueqin Huang Anthony Jorm Colin Mathers Paulo R Menezes Elizabeth Rimmer Marcia Scazufca | 2005 | The Lancet2005，，9503： | 2 |
| 6 | Global prevalence of dementia: a Delphi consensus study显示文摘 | Cleusa P Ferri Martin Prince Carol Brayne Henry Brodaty Laura Fratiglioni Mary Ganguli Kathleen Hall Kazuo Hasegawa Hugh Hendrie Yueqin Huang Anthony Jorm Colin Mathers Paulo R Menezes Elizabeth Rimmer Marcia Scazufca | 2005 | The Lancet . 2005 (9503)2005，，9503： | 2 |
| 7 | A new finite element formulation for computational fluid dynamics: Ⅷ: the Galerkin least squares method for advective diffusive equations显示文摘 | HUGHES T J R FRANCA L P HULBERT G M | 1989 | Computer Methods in Applied Mechanics and Engineering1989，73，2： | 1 |
| 8 | Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters显示文摘 | Wu L F Hughes T R Davierwala A P | 2002 | Nat Genet2002，31，7： | 1 |
| 9 | Formation and use of coal combustion residues from three types power plants burning Illinois coals 显示文摘 | DEMIR I HUGHES R E DEMARIES P J | 2001 | Fuel2001，，80： | 1 |
| 10 | Non-starch polysaccharide-degrading enzymes increase the performance of broiler chickens fed wheat of low apparent metabolizable energy显示文摘 | Choct M J Hughes R P Trimble R | 1995 | J Nutr1995，125，3： | 1 |
| 11 | Ecoregions:an approach to surface water protection显示文摘 | Hughes R M Larsen D P | 1988 | Journal of the Water Pol- lution Control Federation1988，60，： | 1 |
| 12 | Quinalazoline antifolateth ymdiylate synthase inhibitors: Heterocyclic benzoyl ring modifications 显示文摘 | Marsham P R Hughes L R Jackman A L | 1991 | J Med Chem1991，34，5： | 1 |
| 13 | In vitro fermentation by human fecal microflora of wheat arabinoxylans显示文摘 | HUGHES S A SHEWRY P R LI L | 2007 | Journal of Agricultural and Food Chemistry2007，55，11： | 1 |
| 14 | Common variation in the vitamin 0 receptor gene and risk of inflammatory bowel disease in an Irish case-control study显示文摘 | Hughes OJ McManus R Neary P O'morain C O'sullivan M | 2011 | Eu[J Gastroenterol Hepatol2011，23，9： | 1 |
| 15 | Development of cerium-based conversion coatings on 2024-T3 A1 alloy after rare-earth desmutting 显示文摘 | HUGHES A E GORMAN J D MILLER P R SEXTON B A PATERSON P J K TAYLOR R J | 2004 | Surface and Interface Analysis2004，36，44： | 1 |
| 16 | Climate change, human impacts, and the resilience of coralreefs显示文摘 | HUGHES T P BAIRD A H BELLWOOD D R | 2003 | Science2003，301，： | 1 |
| 17 | Sodium as a toxic ion in potassium deficiency 显示文摘 | CANNON P R FRAZIER L E HUGHES R H | 1953 | Metabolism1953，2，4： | 1 |
| 18 | Free-space quantum-key distribution 显示文摘 | Buttler W T Hughes R J Kwiat P G | 1998 | Phys Rev A1998，57，4： | 1 |
| 19 | The perils of shift work : evening shift, night shift and ratating shifts: are they for you 显示文摘 | Hughes R Stone P | 2004 | Am J Nurs2004，104，9： | 1 |
| 20 | Environ- mental and geometric constraints on Indo-Pacific coral reef biodiversity显示文摘 | Bellwood D R Hughes T P Connolly S R | 2005 | Ecol Lett2005，763，： | 1 |
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