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| 1 | 含高钙和维生素D的强化奶能有效提高健康的绝经后的中国女性体内的维生素D水平并减少骨吸收显示文摘目的钙摄入水平低以及体内维生素D不足是导致亚洲女性罹患骨质疏松的危险因素。此项研究的目的是评估高钙维生素D强化牛奶(HCM)对健康的中国绝经后妇女的体内维生素D状态和骨吸收标志物进行干预的影响。方法本试验对象为55岁以上,绝经至少5年的女性。共有124名女性进行了总体健康状况和骨密度检查筛选。63名女性被随机分为对照组和试验组,试验组在12w内每日饮用两次高钙/维生素D强化奶(含900 mg钙、96 mg镁、2.4 mg锌和6.4μg维生素D)。2组分别在试验开始、试验2 w、8 w和12 w时测量血矿物质、25(OH)维生素D3和Ⅰ型胶原C端肽(CTX)水平。结果对照组女性平均年龄为63±4.6岁,高钙强化奶(HCM)组女性平均年龄为62±3.8岁。所测得的每日钙摄入量的基线值为HCM组260~482 mg,对照组为252~692 mg。12 w后HCM组的平均身体质量指数(BMI)显著降低(P<0.05)。HCM组的血25(OH)维生素D3水平显著提高(33.13~39.49 nmol/L),而对照组则维持不变(29.27~28.21 nmol/L)。HCM组的血CTX水平在0 w和2 w之间下降了25%,并保持不变直至第12w。从第2w开始HCM组和对照组相比血CTX水平就出现了显著差异(P<0.001)。结论通过饮用含高钙和维生素D的强化奶(HCM),在2至4w内能显著提高中国绝经妇女体内维生素D水平,并减少骨吸收破坏。如果长期持续地饮用含高钙和维生素D的强化奶(HCM),能减少骨吸收和骨量丢失的风险,从而减少患骨质疏松和由此引起骨折的风险。 | Marlena C Kruger PengCheng Ha Joanne M Todd Barbara Kuhn-Sherlock Linda M Schollum Jiliang Ma George Qin Edith Lau | 2013 | 中国骨质疏松杂志2013，19，2： | 2 |
| 2 | Web Mining for Distance Education显示文摘 | HA H S BAE S M PARK S C | 2002 | IEEE2002，，2： | 1 |
| 3 | Diabetes reporting as a cause of death:results from the Translating Research into Action for Diabetes( TRIAD) study显示文摘 | McWeen LN Kim C Ha an M | 2006 | Diabetes Care2006，29，： | 1 |
| 4 | Ganoderma lucidum mycelia enhance innate immunity by activating NF - kappa B显示文摘 | KUO M C WENG C Y HA C L | 2006 | Journal of Ethnopharmacology2006，103，2： | 1 |
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| 9 | Polymers for flexible displays:From material selection to device applications显示文摘 | Choi M C Kim Y Ha C S | | 0，，06： | 1 |
| 10 | Miscibility of nylon 46 and ethylene-vinyl alcohol copolymer blends 显示文摘 | HA C S CHO W KO M G | 1997 | Polymer1997，38，5： | 1 |
| 11 | Review a definition for dietary fiber显示文摘 | Jarvis M C Mann J I | 2000 | European Journal of Clinical Nutrition2000，54，12： | 1 |
| 12 | Highly transparent o-PDA functionalized ZnS-polymer nanocomposite thin films with high refractive index显示文摘 | Ullah M H Kim J H Ha C S | 2008 | Mater Lett2008，62，16： | 1 |
| 13 | Endothelial dysfunction in diabetes mellitus :molecular mechanisns and clinical implications显示文摘 | Tabit C E Orang W B Ha N M | 2010 | Rev Faldoer Metab Disord2010，11，1： | 1 |
| 14 | A resolver-to-digital conversion method for fast tracking显示文摘 | YIM C H HA I J KO M S | | 0，，05： | 1 |
| 15 | Production of transgenic tall fescue and red fescue plants by particle bombardment of mature seed-derived highly regenerative tissues显示文摘 | Cho M J Ha C D Lemaux P G | 2000 | Plant Cell Reports2000，19，11： | 1 |
| 16 | Lymphoma of the nasal cavity and paranasal sinuses:improved outcome and altered prognostic factors with combined modality therapy显示文摘 | Logsdon M Ha C Kavadi V | 1997 | Cancer1997，80，3： | 1 |
| 17 | Effect of chronic coadministraton of endotoxin and ethand on rat liver pathology and proinflammatort and anti-inflammatory cytokine显示文摘 | Jarvelainen HA Fang C Ingelman-Sundberg M | 1999 | Hepatology1999，29，5： | 1 |
| 18 | Production of transgenic tall rescue and red rescue plants by particle bombardment of mature seed derived highly regenerative tissues显示文摘 | Cho M J Ha C D Lemaux P G | 2000 | Plant Cell Reports2000，19，： | 1 |
| 19 | IgG expression in trophoblasts de- rived from placenta and gestational trophoblastic disease and its role in regulating invasion 显示文摘 | YANG M HA C LIU D | 2014 | Immunol Res2014，，： | 1 |
| 20 | Changes in microcystin production by Microcystis aeruginosa exposed to phytoplanktivorous and omnivorous fish显示文摘 | JANG M H HA K LUCAS M C | 2004 | Aquatic Toxicology2004，68，1： | 1 |
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