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1血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物.Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) 2020中华高血压杂志2020,28,5:9
2Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients.Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder 2009World Journal of Gastroenterology2009,15,9:6
3Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogenactivated protein kinase in mouse lung显示文摘Xin-qi PENG Mahendra DAMARLA Jarrett SKIRBALL Stephanie NONAS Xiao-ying WANG Eugenia J HAN Emile J HASAN Xuan CAO Adel BOUEIZ Rachel DAMICO Rubin M TUDER Alfred M SClUTO Dana R ANDERSON Joe GNGARCIA David A KASS Paul M HASSOUN Jun-tian ZHANG 2010Acta Pharmacologica Sinica2010,31,2:6
4残余应力导致三层聚烯烃管道防腐层剥离与开裂显示文摘这是美国运输部发起的研究项目,一个管道防腐层专家团队参与了本研究项目,评价了三层聚烯烃管道外防腐涂层(3LPO)的完整性。研究表明,三层聚烯烃管道外防腐涂层(3LPO)存在剥离和面层开裂两大完整性问题。过去几年里,据文献报道,三层聚烯烃管道外防腐涂层(3LPO)的熔结环氧粉末(FBE)底漆与钢管界面上发生多起防腐层剥离事故,以及聚丙烯(PP)面层发生开裂事故。这些防腐层事故引起人们对使用三层聚烯烃管道外防腐涂层(3LPO)的关注。一般来讲,三层聚烯烃管道外防腐涂层(3LPO)采用比较厚的聚烯烃面层增强防腐层抗机械损伤和防止水渗透的能力。但是,聚烯烃的热膨胀系数比钢材高得多,结果在防腐层系统里产生比较高的残余热应力。因为残余应力高,造成防腐层剥离,尤其在管端截短防腐层和任何防腐层的边上,因为这些是高应力集中部位。特别是假如钢管表面预处理不当,就无法保证防腐层持久达到很强的粘合强度。如果熔结环氧粉末(FBE)底漆配方选择不当,发生热氧化降解,也导致防腐层过早失效。如果使用温度很高,聚丙烯也会因为热氧化降解而变脆。在残余应力下,这样脆性的聚丙烯面层就会开裂。本文分析了三层聚烯烃管道外防腐涂层(3LPO)中的残余应力,并且探讨了残余应力对三层聚烯烃管道外防腐涂层(3LPO)剥离和聚丙烯(PP)面层开裂机理的影响。B.T.A.Cheng S Hung-jue J Han D Wong A Kehr M Mallozzi F Aguirre H Pham W Snider 王向农(译) 2011防腐保温技术2011,19,3:3
5Successful operation of a cooperative SLR station of China and Argentina in San Juan显示文摘We introduced the observations and researches using a Satellite Laser Ranging (SLR) system with high precision, which was designed and made in China and installed in the Observatory of San Juan Uni- versity, Argentina, the capability of the system and the achievement of the cooperative procedure be- tween China and Argentina. The SLR station in San Juan, set up by China and Argentina, is quite sig- nificant for improving the distribution of SLR stations and enhancing the orbital coverage of the whole earth. Since the SLR system started to work in the Observatory of San Juan University in the beginning of 2006, the operation is rather good, and rich data with high precision have been obtained. Further plan of the cooperation for the near future is also presented.HAN YanBen LIU WeiDong E ACTIS R PODESTA WANG TanQiang GUO TangYong QU Feng A M PACHECO A A GONZALEZ E ALONSO XIANG QingGe HUANG DongPing YIN ZhiQiang 2008Chinese Science Bulletin2008,53,16:2
6短期常压低氧步行训练对肥胖成年人运动能力和步态的影响显示文摘为了比较以个人喜好的步行速度(preferred walking speed,PWS)短期低氧与常氧训练对肥胖患者的能量、力学、效率和代谢风险标志物的影响,Fernández Menéndez等纳入肥胖患者23例,在缺氧[海拔3km,n=12;体质量指数(body mass index,BMI)(34.0±0.8)kg/m2]或常氧[海拔360m,n=11;BMI(32.9±0.8)kg/m2]情况下.刘青 叶鹏 Fernández Menéndez A Saudan G Sperisen L Hans D Saubade M Millet GP Malatesta D 2018中华高血压杂志2018,26,6:2
7Glycosaminoglycans enhance human leukemic cell growth in vitro显示文摘Maurer A M Han Z C Dhermy D 1994Leuk Res1994,18,11:2
8前列腺癌pT3亚型细分建议:精囊侵犯加前列腺腺外扩散比单独精囊侵犯的生化复发和淋巴结转移率更高显示文摘2020年美国前列腺癌发病率为21%,病死率为10%。术前血清PSA、预后分期肿瘤淋巴结转移、手术切缘状态和组织学分级[格里森评分和国际泌尿外科病理学会(ISUP)分组]被列为最高级别(Ⅰ类)证据。AJCC第8版TNM分期将前列腺癌pT3分为pT3a和pT3b,前者仅前列腺腺外扩散(EPE),后者为精囊侵犯(SVI)伴或不伴EPE。方三高(摘译) 魏建国(审校) Rehman A El-Zaatari Z M Han S H 2022临床与实验病理学杂志2022,38,3:2
9Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies.Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo 2017World Journal of Hepatology2017,9,14:2
10Modeling piezoelectric actuators显示文摘 Willem L 2000IEEE/ASME Transactions on Mechatronics2000,5,4:1
11Benefits of Soy Isoflavone Therapeutic Regimen on Menopausal Symptoms显示文摘Han K K Soares J M Haidar M A 2002Obstet Gynecol2002,99,3:1
12STATCOM impact study on the integration of a large wind farm into a weak loop power system显示文摘HAN Chong HUANG A Q BARAN M E 2008IEEE Transactions on Energy Conversion2008,23,1:1
13Genetic diversityand recombination of porcine sapoviruses显示文摘WANG Q H HAN M G FUNK J A 2005J Clin Microbiol2005,43,12:1
14Influence of various P/NandP/P ligands on the palladium-catalysed reductive carbonylation of nitrobenzene显示文摘Wehman P Hans M A van Donge 1997J Organomet Chem1997,535,:1
15Microstructure and hydrogenation behavior of ball-milled and melt-spun Mg-10Ni-2Mm alloys 显示文摘WU Y HAN W ZttOU S X LOTOTSKY M V SOLBERG J K YARTYS V A 2008J Alloys Compd2008,466,12:1
16Two-photon-excited fluorescence imaging of human RPE cells with a femtosecond Ti: Sapphire laser显示文摘Bindewald-Wittich A Han M Schmitz-Valckenberg S Snyder Sar- ah R Giese G Bille Josef F 2006Invest Ophthalmol Vis Sci2006,47,10:1
17Network model- ing links breast cancer susceptibility and centrosome dysfunc- tion显示文摘Pujana M A Han J D J Starita L M 2007Nat Genet2007,39,11:1
18Clinical value of 18F-FDG PET-CT in detectingprimary tumor for patients with carcinoma of unknown primary显示文摘Han A Xue J Hu M 2012CancerEpidemiol2012,36,5:1
19Analysis of mixed inverter-rectifier multi-infeed HVDC systems显示文摘CHEN Xiuyu GOLE A M HAN Minxiao 2012IEEE Transactions on Power Delivery2012,27,3:1
20Loss of Halophytism by Interference with SOS1 Expression1[W][OA]显示文摘Oh Dong-Ha Leidi Eduardo Zhang Quan Hwang Sung-Min Li Youzhi Quintero Francisco J Jiang Xingyu D’Urzo Matilde Paino Lee Sang Yeol Zhao Yanxiu Bahk Jeong Dong Bressan Ray A Yun Dae-Jin Pardo José M Bohnert Hans J 2009Plant Physiology2009,,1:1
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