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| 1 | Hepatocellular carcinoma surveillance:An evidence-based approach显示文摘Hepatocellular carcinoma(HCC) makes up 75%-85% of all primary liver cancers and is the fourth most common cause of cancer related death worldwide. Chronic liver disease is the most significant risk factor for HCC with 80%-90% of new cases occurring in the background of cirrhosis. Studies have shown that early diagnosis of HCC through surveillance programs improve prognosis and availability of curative therapies. All patients with cirrhosis and high-risk hepatitis B patients are at risk for HCC and should undergo surveillance. The recommended surveillance modality is abdominal ultrasound(US) given that it is cost effective and noninvasive with good sensitivity. However, US is limited in obese patients and those with non-alcoholic fatty liver disease(NAFLD). With the current obesity epidemic and rise in the prevalence of NAFLD, abdominal computed tomography or magnetic resonance imaging may be indicated as the primary screening modality in these patients. The addition of alpha-fetoprotein to a surveillance regimen is thought to improve the sensitivity of HCC detection.Further investigation of serum biomarkers is needed. Semiannual screening is the suggested surveillance interval. Surveillance for HCC is underutilized and low adherence disproportionately affects certain demographics such as nonCaucasian race and low socioeconomic status. | Patrick S Harris Ross M Hansen Meagan E Gray Omar I Massoud Brendan M McGuire Mohamed G Shoreibah | 2019 | World Journal of Gastroenterology2019，25，13： | 31 |
| 2 | 针对患者利益的机器学习和人工智能研究:在透明性、可重复性、伦理和有效性等方面的20个关键问题显示文摘机器学习(ML)、人工智能(AI)和其他现代统计方法正为利用先前尚未开发且极速增长的数据资源提供新的机会,以期让患者获益。尽管目前正在进行许多有前景的研究,特别是在图像方面,但就文献整体而言还缺乏透明度、对可重复性清晰的阐述、对潜在伦理问题的探究,以及对有效性的明确验证。这些问题的存在有许多原因,其中最重要的一点(为此我们提供了初步解决方案)就是当前缺乏针对ML和AI的最佳实践指南。我们认为从事研究的跨学科团队和应用ML/AI影响健康的项目,将因解决有关透明度、可重复性、伦理和有效性(TREE)的一系列问题而受益。这里提出的20个关键问题为研究团队提供了一个研究设计、实施和报告框架;帮助编辑和同行评审专家评估文献的贡献;让患者、临床医生和政策制定者评估新发现可能会给患者带来的获益。 | Sebastian Vollmer Bilal A Mateen Gergo Bohner Franz J Kirdly Rayid Ghani Pall Jonsson Sarah Cumbers Adrian Jonas Katherine S L McAllister Puja Myles David Granger Mark Birse Richard Branson Karel G M Moons Gary S Collins John P A Chris Holmes Harry Hemingwayp 李峰(译) 徐磊(校) 赵邑(校) | 2020 | 英国医学杂志中文版2020，23，9： | 5 |
| 3 | 糖尿病患者累积收缩压负荷与心血管病风险的关系显示文摘该研究旨在评估2型糖尿病患者累积收缩压负荷与心血管事件风险的关系。方法:对百普乐和达美康缓释片对糖尿病和血管疾病的对照评估试验的观察性研究(action in diabetes and vascular disease preterax and diamicron MR controlled evaluation post trial observational study, ADVANCE-ON)中的2型糖尿病患者进行事后分析。 | Wang N Harris K Hamet P Harrap S Mancia G Poulter N Williams B Zoungas S Woodward M Chalmers J Rodgers A 刘青(译) 郑武洪(审校) | 2022 | 中华高血压杂志2022，30，12： | 2 |
| 4 | Frictional characteristics of teflon-steel interfaces under dynamic conditions显示文摘 | Constantinou M C Caccese J Harris H G | 1987 | Earthquake Engineering and Structural Dynamics1987，15，6： | 1 |
| 5 | The Effect of Financial Liberalization on the Capital Structure and Invest- ment Decisions of Indonesian Manufacturing Establishments 显示文摘 | Harris J R Schiantarelli F Siregar M G | 1994 | World Bank Economic Review1994，8，1： | 1 |
| 6 | Plasmas as antennas: Theory, experiment and applications显示文摘 | Borg G G Harris J H Martin N M etal | 2000 | Phys Plasmas2000，7，7： | 1 |
| 7 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 8 | Change in eco system service values in the San Antonio area, Texas显示文摘 | Kreuter U P Harris H G Matlock M D | 2001 | Eco- logical Economics2001，39，3： | 1 |
| 9 | Screening for asymptomtic deep vein thrombosis in surgical intensive care patients显示文摘 | Harris L M Curl G R Booth F V | 1997 | J Vasc Surg1997，26，6： | 1 |
| 10 | Phosphate-induced metal immobilization in a contaminated site 显示文摘 | CAO R X MA L Q CHEN M SINGH S P HARRIS W G | 2003 | Environmental Pollution2003，122，： | 1 |
| 11 | Carbon foot- printing of lamb and beef production systems: insights from an empirical analysis of farms in Wales, UK显示文摘 | Edwards-Jones G Plassmann K Harris I M | 2009 | The Journal of Agricultural Science2009，147，6： | 1 |
| 12 | Factors affecting local recurrence of colonic adenocarcinoma 显示文摘 | Harris G J Church J M Senagore A J | 2002 | Dis Colon Rectum2002，45，8： | 1 |
| 13 | Expression of bone morphogenetic protein-7 mRNA in normal and is chemic adult rat kidney 显示文摘 | Simon M Maresh J G Harris S E | 1999 | Am J Physiol1999，276，： | 1 |
| 14 | Personality and Team Performance : A Meta - Analysis 显示文摘 | Miranda A G Peeters Harrie F J M Vantuijl Christel G Rutte Isabelle M M J Reymen | 2006 | European Journal of Personality2006，，20： | 1 |
| 15 | Psy-chometrically equivalent Russian speech audiometrymaterials by male and female talkers显示文摘 | HARRIS R W NISSEN S L POLA M G | 2007 | Int J Audiol2007，46，： | 1 |
| 16 | The reaction of epoxides with thiourea显示文摘 | Bordwell F G Harry M Andersen | 1953 | J Amer Chem Soc1953，75，： | 1 |
| 17 | Ratoon stunting disease of sugarcane: isolation of the causal bacterium显示文摘 | Davis M J Gillaspie A G Harris R W | 1980 | Science1980，210，4476： | 1 |
| 18 | Change in ecosystem service values in the San Antonio area, Texas显示文摘 | Kreuter U P Harris H G Matlock M D | 2001 | Ecological Economics2001，39，3： | 1 |
| 19 | En- donasal laser dacryocytorhinosromy 显示文摘 | MASSARO B M GONNERING R S HARRIS G J | 1990 | Arch Ophthalmol1990，108，： | 1 |
| 20 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion 显示文摘 | Martinez D Challacombe J Morgenstern 1 Hibbett D Schmoll M Kubicek CP Ferreira P Ruiz-Duenas FJ Martinez AT Kersten P Hammel KE Wymelenberg AV Gaskell J Lindquist E Sabat G BonDurant SS Larrondo LF Canessa P Vicuna R Yadav J Doddapaneni H Subramanian V Pisabarro AG Lavin JL Oguiza JA Master E Henrissat B Coutinho PM Harris P Magnuson JK Baker SE Bruno K Kenealy W Hoegger PJ Kties U Ramaiya P kucas S Salamov A Shapiro H Tu H Chee CL Misra M Xie G Teter S Yaver D James T Mokrejs M Pospisek M Grigoriev IV Brettin T Rokhsar D Berka R Cullen D | 2009 | PNAS2009，106，6： | 1 |
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