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| 1 | 酒精摄入、心脏生物标志物和心房颤动风险与不良结局显示文摘酒精摄入和新发心房颤动相关性证据不一,尤其是在低剂量下。该研究评估欧洲队列在整个饮酒范围内酒精摄入、生物标志物和新发心房颤动的关系。方法和结果:在一个以社区为基础的汇集队列中,研究者随访107845人,以评估酒精摄入(酒精种类和饮酒方式)与新发心房颤动的关系。研究者收集经典心血管病危险因素和新发心力衰竭的信息,并检测生物标记物氨基末端脑钠肽前体和高敏肌钙蛋白I。 | 陈嘉睿(译) 练桂丽((审校) Csengeri D Sprünker NA Di Castelnuovo A Niiranen T Vishram-Nielsen JK Costanzo S S derberg S Jensen SM Vartiainen E Donati MB Magnussen C Camen S Gianfagna F L chen ML Kee F Kontto J Mathiesen EB Koenig W Stefan B de Gaetano G J rgensen T Kuulasmaa K Zeller T Salomaa V Iacoviello L Schnabel RB | 2021 | 中华高血压杂志2021，29，2： | 9 |
| 2 | Evaluation of chronic kidney disease in chronic heart failure: From biomarkers to arterial renal resistances显示文摘Chronic kidney disease and its worsening are recurring conditions in chronic heart failure(CHF) which are independently associated with poor patient outcome.The heart and kidney share many pathophysiological mechanisms which can determine dysfunction in each organ. Cardiorenal syndrome is the condition in which these two organs negatively affect each other, therefore an accurate evaluation of renal function in the clinical setting of CHF is essential. This review aims to revise the parameters currently used to evaluate renal dysfunction in CHF with particular reference to the usefulness and the limitations of biomarkers in evaluating glomerular dysfunction and tubular damage. Moreover, it is reported the possible utility of renal arterial resistance index(a parameter associated with abnormalities in renal vascular bed) for a better assesment of kidney disfunction. | Massimo Iacoviello Marta Leone Valeria Antoncecchi Marco Matteo Ciccone | 2015 | World Journal of Clinical Cases2015，3，1： | 8 |
| 3 | Non-invasive evaluation of arrhythmic risk in dilated cardiomyopathy:From imaging to electrocardiographic measures显示文摘Malignant ventricular arrhythmias are a major adverse event and worsen the prognosis of patients affected by ischemic and non-ischemic dilated cardiomyopathy.The main parameter currently used to stratify arrhythmic risk and guide decision making towards the implantation of a cardioverter defibrillator is the evaluation of the left ventricular ejection fraction.However,this strategy is characterized by several limitations and consequently additional parameters have been suggested in order to improve arrhythmic risk stratification.The aim of this review is to critically revise the prognostic significance of non-invasive diagnostic tools in order to better stratify the arrhythmic risk prognosis of dilated cardiomyopathy patients. | Massimo Iacoviello Francesco Monitillo | 2014 | World Journal of Cardiology2014，6，7： | 5 |
| 4 | Heart failure in elderly: progress in clinical evaluation and therapeutic approach显示文摘Chronic heart failure (CHF) represents a major and growing health problem, due to its high incidence and prevalence, its poor prognosis and its impact on health-care costs. Although CHF patients are mainly elderly, few studies were aimed at testing the efficacy of diagnostic and therapeutic approaches in this population. The difficulty in CHF diagnosis among the elderly is related to different factors, such as: the frequent presence of co-morbidity conditions mimicking or masking heart failure signs and symptoms; the different diagnostic cut-offs of natriuretic peptides; and the need to correctly evaluate diastolic function in order to assess CHF with preserved ejection fraction. Furthermore,the therapy of elderly CHF patients has not beenwell defined, considering the few studies involving very aged patients and the absence of a therapeutic strategy demonstrated to improve prognosis of CHF patients with preserved ejection fraction. The aim of this review is to focus on the most recent issues concerning the diagnosis and therapy of elderly patients affected byCHF. | Massimo Iacoviello Valeria Antoncecchi | 2013 | Journal of Geriatric Cardiology2013，10，2： | 3 |
| 5 | Role of imaging in the evaluation of renal dysfunction in heart failure patients显示文摘Heart failure and kidney disease share common pathophysiological pathways which can lead to mutual dysfunction,known as cardiorenal syndrome.In heart failure patients,renal impairment is related to hemodynamic and nonhemodynamic factors.Both decreased renal blood flow and renal venous congestion due to heart failure could lead to impaired renal function.Kidney disease and worsening renal function are independently associated with poor prognosis in heart failure patients,both in acute and chronic clinical settings.The aim of this review is to assess the role of renal imaging modalities in the evaluation and management of heart failure patients.Renal imaging techniques could complete laboratory data,as estimated glomerular filtration rate,exploring different pathophysiological factors involved in kidney disease and adding valuable information about renal structure and function.In particular,Doppler examination of arterial and venous hemodynamics is a feasible and non invasive technique,which has proven to be a reliable method for prognostic stratification in patients with cardiorenal syndrome.The renal resistance index,a measure related to renal hemodynamics,can be calculated from the Doppler evaluation of arterial flow.Moreover,the analysis of Doppler venous flow patterns can integrate information from the arterial study and evaluate renal congestion.Other imaging modalities are promising,but still confined to research purposes. | Dario Grande Paola Terlizzese Massimo Iacoviello | 2017 | World Journal of Nephrology2017，6，3： | 3 |
| 6 | Predicting mortality in patients with acute heart failure:Role of risk scores显示文摘Acute heart failure is a leading cause of hospitalization and death,and it is an increasing burden on health care systems. The correct risk stratification of patients could improve clinical outcome and resources allocation,avoiding the overtreatment of low-risk subjects or the early,inappropriate discharge of high-risk patients. Many clinical scores have been derived and validated for in-hospital and post-discharge survival; predictive models include demographic,clinical,hemodynamic and laboratory variables. Data sets are derived from public registries,clinical trials,and retrospective data. Most models show a good capacity to discriminate patients who reach major clinical end-points,with C-indices generally higher than 0.70,but their applicability in realworld populations has been seldom evaluated. No study has evaluated if the use of risk score-based stratification might improve patient outcome. Some variables(age,blood pressure,sodium concentration,renal function) recur in most scores and should always be considered when evaluating the risk of an individual patient hospitalized for acute heart failure. Future studies will evaluate the emerging role of plasma biomarkers. | Andrea Passantino Francesco Monitillo Massimo Iacoviello Domenico Scrutinio | 2015 | World Journal of Cardiology2015，7，12： | 3 |
| 7 | Ventricular repolarization measures for arrhythmic risk stratification显示文摘Ventricular repolarization is a complex electrical phenomenon which represents a crucial stage in electrical cardiac activity. It is expressed on the surface electrocardiogram by the interval between the start of the QRS complex and the end of the T wave or U wave(QT). Several physiological, pathological and iatrogenic factors can influence ventricular repolarization. It has been demonstrated that small perturbations in this process can be a potential trigger of malignant arrhythmias, therefore the analysis of ventricular repolarization represents an interesting tool to implement risk stratification of arrhythmic events in different clinical settings. The aim of this review is to critically revise the traditional methods of static analysis of ventricular repolarization as well as those for dynamic evaluation, their prognostic significance and the possible application in daily clinical practice. | Francesco Monitillo Marta Leone Caterina Rizzo Andrea Passantino Massimo Iacoviello | 2016 | World Journal of Cardiology2016，8，1： | 2 |
| 8 | House prices, borrowing constraints, and monetary policy in the business cycle 显示文摘 | Iacoviello M | 2005 | American Economic Review2005，95，3： | 1 |
| 9 | Analysis of gene environment interaction in coronary heart disease:fibrinogen polymorphisms as an example显示文摘 | Michela Vischetti Francesco Zito Maria Benedetta Donati Licia Iacoviello | 2002 | Ital Heart J2002，3，： | 1 |
| 10 | Prognostic role of sub- clinical hypothyroidism in chronic heart failure outpatients显示文摘 | IACOVIELLO M GUIDA P GUASTAMACCHIA E et ol | 2008 | Curr Pharm Des2008，14，26： | 1 |
| 11 | Genetic variation in the renin-angiotensin system and abdominal adiposity in men: the Olivetti Prospective Heart Study显示文摘 | Strazzullo P Iacone R Iacoviello L | 2003 | Ann Intern Med2003，138，： | 1 |
| 12 | Consumption,House Prices and Collateral Constraints显示文摘 | Iacoviello M | 2004 | Journal of Housing Economics2004，，4： | 1 |
| 13 | Chlamydia pneumoniae and cytomegalovirus seropositivity, inflammatory markers, and the risk of myocardial infarction at a young age 显示文摘 | Iacoviello L Colombo M | 2001 | Am Heart J2001，142，： | 1 |
| 14 | Cardiac resynchronization therapy tailored by echocardiography evaluation of ventricular asynchrony显示文摘 | Pitzalis MV Iacoviello M Romito R | 2002 | J Am Coll Cardiol2002，40，9： | 1 |
| 15 | Microstructure influence on fatigue crack propagation in sintered stainless steels 显示文摘 | IACOVIELLO F | 2005 | International Journal of Fatigue2005，27，： | 1 |
| 16 | Prognostic role of sub-clinical hypothyroidism in chronic heart failure outpatients显示文摘 | Edoardo Guastamacchia1 Vincenzo Triggiani1 Massimo Iacoviello | 2009 | Cur Pharm Des2009，14，26： | 1 |
| 17 | Relation of the 174 G/C polymorphism of inter leukin-6 to inter leukin-6 plasma levels and to length of hospitalization after surgi-cal coronary revasculariza-tion显示文摘 | Burzota F Iacoviello L Dicastelnuovo A | 2001 | Am J cardiol2001，88，： | 1 |
| 18 | Housing Prices,Borrow Constraints and Monetary Policy in the Business Cycle显示文摘 | Iacoviello M | | 0，，03： | 1 |
| 19 | House Prices, Borrowing Con- straints and Monetary Policy in the Business Cycle 显示文摘 | Iacoviello M | 2005 | American Economic Review2005，95，3： | 1 |
| 20 | Depression but not anxiety influences the autonomic control of heart rate after myocardial infarction显示文摘 | Iacoviello M Todarello O | 2001 | Am Heart J2001，141，： | 1 |
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