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| 1 | Human colorectal cancer-specific CCAT1-L IncRNA regulates long-range chromatin interactions at the MYC locus显示文摘人的 8q24 基因沙漠包含多重 enhancers 形式织物特定的远程的染色质与 MYC oncogene 循环,但是染色质在 MYC 地点循环怎么被调整,仍然保持糟糕理解。这里,我们表明那长 noncoding RNA (lncRNA ) , CCAT1-L,从一个地点在人的 colorectal 癌症明确地被抄录 MYC 在上游的 515 kb。这 lncRNA 在 MYC transcriptional 规定起一个作用并且支持远程的染色质循环。重要地, CCAT1-L 地点位于强壮的超级提高以内并且离 MYC 空间地靠近。CCAT1-L 击倒在 MYC 倡导者和它的 enhancers 之间的减少的远程的相互作用。另外, CCAT1-L 与 CTCF 交往并且在这些环区域调制染色质符合构造。这些结果揭示一个重要角色一以前在在 MYC 地点的基因规定的 unannotated lncRNA。 | Jian-Feng Xiang Qing-Fei Yin Tian Chen Yang Zhang Xiao-Ou Zhang Zheng Wu Shaofeng Zhang Hai-Bin Wang Junhui Ge Xutiua Lu Li Yang Ling-Ling Chen | 2014 | Cell Research2014，24，5： | 67 |
| 2 | Shortened Basal Internodes Encodes a Gibberellin 2-Oxidase and Contributes to Lodging Resistance in Rice显示文摘改进住宿抵抗的繁殖半矮子变化被证明了在自从绿 revolution.?However 的来临,增加谷物产量极其成功,在亚洲繁殖半矮子米饭变化的多数主要依赖于 SD1 的变异的等位基因的基因介绍,它编码赤霉素( GA ) 20-oxidase , OsGA20ox2 ,为催化 GA 生合成。这里,我们报导新米饭住宿抵抗基因,弄短的基础 Internodes (SBI ) ,它编码赤霉素 ? 2-oxidase 并且明确地控制灰煤杆的延伸通过撤销的基础 internodes GA 活动。SBI 主要在灰煤杆被表示基础 internodes。基因分析显示 SBI 是影响米饭高度和住宿抵抗的半主导的基因。SBI 突变而产生之遗传的变体显示不同活动并且与米饭变化的高度被联系。与 SBI 等位基因的更高的活动繁殖与改进住宿抵抗和增加的产量产生新米饭变化。SBI 的发现为生产半矮子米饭显型提供一个理想的基因资源并且为与提高的住宿抵抗和高产量引起米饭变化提供有效策略。 | Chang Liu Jinshan Gui Chenjian Fu Hasi Yu Dongliang Song Junhui Shen Peng Qin Xuanming Liu Bin Han Yuanzhu Yang Laigeng Li | 2018 | Molecular Plant2018，11，2： | 33 |
| 3 | Investigation on structural optimization of anti-overturning slipper of axial piston pump显示文摘Improving the carrying ability of oil film between slipper and swash plate and reducing the partial abrasion of slipper are important to improve the service life and reliability of axial piston pump.In this paper,a numerical simulation model was developed for slipper/swash-plate friction pair based on the elastohydrodynamic theory.The dynamic micro-motion and pressure distribution of slipper were analyzed and it was pointed out that the tilt of slipper was the main reason for its partial abrasion.The simulations about the slippers with different slopes on the outer edge of the sealing belt showed that the partial abrasion could reduce the carrying ability and increase the leakage of the slipper/swash-plate pair.The proper slope on the inner edge helped to improve the carrying ability and reduce the leakage of slipper.The experimental tests were in accord with the simulation results to a great extent,showing that the simulation model had a high accuracy and could be applied to the design and optimization of slipper,and that the slipper with optimal inner slope provided an encouraging method to improve the efficiency and reliability of axial piston pump. | XU Bing ZHANG JunHui YANG HuaYong | 2012 | Science China(Technological Sciences)2012，55，11： | 30 |
| 4 | Investigation on the Radial Micro-motion about Piston of Axial Piston Pump显示文摘The limit working parameters and service life of axial piston pump are determined by the carrying ability and lubrication characteristic of its key friction pairs. Therefore, the design and optimization of the key friction pairs are always a key and difficult problem in the research on axial piston pump. In the traditional research on piston/cylinder pair, the assembly relationship of piston and cylinder bore is simplified into ideal cylindrical pair, which can not be used to analyze the influences of radial micro-motion of piston on the distribution characteristics of oil-film thickness and pressure in details. In this paper, based on the lubrication theory of the oil film, a numerical simulation model is built, taking the influences of roughness, elastic deformation of piston and pressure-viscosity effect into consideration. With the simulation model, the dynamic characteristics of the radial micro-motion and pressure distribution are analyzed, and the relationships between radial micro-motion and carrying ability, lubrication condition, and abrasion are discussed. Furthermore, a model pump for pressure distribution measurement of oil film between piston and cylinder bore is designed. The comparison of simulation and experimental results of pressure distribution shows that the simulation model has high accuracy. The experiment and simulation results demonstrate that the pressure distribution has peak values that are much higher than the boundary pressure in the piston chamber due to the radial micro-motion, and the abrasion of piston takes place mainly on the hand close to piston ball. In addition, improvement of manufacturing roundness and straightness of piston and cylinder bore is helpful to improve the carrying ability of piston/cylinder pair. The proposed research provides references for designing piston/cylinder pair, and helps to prolong the service life of axial piston pump. | XU Bing ZHANG Junhui YANG Huayong ZHANG Bin | 2013 | Chinese Journal of Mechanical Engineering2013，26，2： | 26 |
| 5 | Future 5G-Oriented System for Urban Rail Transit:Opportunities and Challenges显示文摘As a development direction of urban rail transit system,the train autonomous circumambulate system(TACS)can operate in a safer,more efficient,and more economical mode.However,most urban rail transit systems transmit signals through industrial,scientific,and medical(ISM)frequency bands or narrow frequency bands,which cannot meet the requirements of TACS.As a promising solution,the 5th generation(5G)mobile communication provides more services for the future urban rail transit systems,and covers the shortages of exiting communication technologies in terms of capacity and reliability.In this paper,we first briefly review the research status of current train control system and introduce its limitations.Next,we propose a novel network architecture,and present new technologies and requirements of the proposed architecture for TACS.Some potential challenges are then discussed to give insights for further research of TACS. | Junhui Zhao Jin Liu Lihua Yang Bo Ai Shanjin Ni | 2021 | China Communications2021，18，2： | 18 |
| 6 | Designer TAL Effectors Induce Disease Susceptibility and Resistance to Xanthomonas oryzae pv. Oryzae in Rice显示文摘TAL (抄写像使活跃之物) 从 Xanthomonas 细菌的受动器激活血缘的主人基因,在主人目标基因的基因上下文上导致疾病危险性或抵抗依赖者。模块化的性质和 TAL 受动器的 DNA 识别代码启用为基因激活的设计者 TAL 受动器(dTALE ) 特定工程。然而, dTALEs 的可行性作为为基因的抄写使活跃之物,功能的分析没被表明。这里,我们报导 dTALEs 的使用,由病原的 Xanthomonas oryzae pv 表示了并且交付。oryzae (Xoo ) ,在揭示,二的新功能以前在 rice/Xoo 相互作用为疾病危险性识别了疾病相关的基因和一发展基因的潜力。dTALE 基因 dTALE-xa27,设计了指向抵抗基因 Xa27 的易受影响的等位基因,在不那样易受影响的米饭栽培变种 IR24 得到了抵抗反应。四 dTALE 基因被做导致四四导致的象 Xa27 一样基因的在米饭栽培变种 Nipponbare 的注解 Xa27 相应基因,而是没有授与抵抗到包含 dTALE Xoo 种类。dTALE 基因也被产生激活后退的抵抗基因 xa13,疾病危险性基因 Os8N3 的等位基因(也命名的 Xa13 或 OsSWEET11,蔗糖流出 transporter 的一个成员香甜的基因家庭) 。由 dTALE 的 xa13 的正式就职显示了抵抗米饭 IRBB13 (xa13/xa13 ) 产生 Xoo。最后, OsSWEET12,到 Xoo 的当还,没有相应自然地发生的 TAL 受动器的 uncharacterized 糖果基因识别的、授与的危险性尽力表示相应 dTALE 基因。我们的结果证明 dTALEs 能通过细菌的分泌物系统被交付在植物为功能的分析激活兴趣的基因。 | Ting Li Sheng Huang Junhui Zhou Bing Yang | 2013 | Molecular Plant2013，6，3： | 14 |
| 7 | Hydraulic operating mechanisms for high voltage circuit breakers: Progress evolution and future trends显示文摘High voltage circuit breakers are the most important protection and control apparatus in power system. As a core part of circuit breakers,the operating mechanisms have a trend to be hydraulic-style in high voltage power grid. Compared with other hydraulic systems,the hydraulic operating mechanisms have the characteristics of high hydraulic pressure,high speed,high power and long-term waiting etc.,and it is because of the characteristics that the hydraulic operating mechanisms become difficult to be developed and have been arousing significant study interest from more and more researchers as well as their promising applications. Therefore,it is significant to summarize the hydraulic operating mechanisms on their development,characteristics,and key technologies etc. In this review,the evolution process and recent studies of hydraulic operating mechanisms at home and abroad are viewed. The review then focuses on the characteristics and key technologies of hydraulic operating mechanisms,especially on time and velocity characteristics,high-speed cylinder cushioning,fast response and great flow rate control valve,temperature compensation,system monitoring and fault diagnosis,intelligent operation,energy storage module,etc. In the end,the future trends of this field are presented. | LIU Wei XU Bing YANG HuaYong ZHAO HongFei WU JunHui | 2011 | Science China(Technological Sciences)2011，54，1： | 10 |
| 8 | Dissecting the Genetic Basis of Grain Shape and Chalkiness Traits in Hybrid Rice Using Multiple Collaborative Populations显示文摘 | Junyi Gong Jiashun Miao Yan Zhao Qiang Zhao Qi Feng Qilin Zhan Benyi Cheng Junhui Xia Xuehui Huang Shihua Yang Bin Han | 2017 | Molecular Plant2017，10，10： | 8 |
| 9 | Microscopic examination of intracellular organisms in bronchoalveolar lavage fluid for the diagnosis of ventilator-associated pneumonia:a prospective multi-center study显示文摘 | Liu Chang Du Zhaohui Zhou Qing Hu Bo Li Zhifeng Yu Li Xu Tao Fan Xuepeng Yang Junhui Li Jianguo | 2014 | Chinese Medical Journal2014，，10： | 6 |
| 10 | A quasi-automated generation control strategy for multiple energy storage systems to optimize low-carbon benefits显示文摘Integrating a battery energy storage system(ESS)with a large wind farm can smooth the intermittent power obtained from the wind farm,but the smoothing function will not be achieved if multiple ESSs are used to smooth the fluctuations in individual wind power plants in a distributed pattern.Therefore,this study focuses on the development of a control strategy to optimize the use of multiple ESSs to accelerate the adoption of wind energy resources.This paper proposes a quasi-automated generation control(QAGC)strategy to coordinate multiple ESSs,which responds to the grid dispatch demand rather than smoothing out the intermittent power from individual wind farms.The aims of QAGC are to ensure that multiple ESSs provide a service that is as balanced as possible,so more wind power systems at various scales can be accepted by the grid,as well maximizing the low-carbon benefits of ESSs.The effectiveness of QAGC is demonstrated by using data from an actual gigawatt scale cluster of wind plants. | Gangui YAN Xudong ZHENG Gang MU Junhui LI Yang CUI Yue WANG | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，1： | 6 |
| 11 | Nb2C MXene-Functionalized Scaffolds Enables Osteosarcoma Phototherapy and Angiogenesis/Osteogenesis of Bone Defects显示文摘Early surgical resection and chemotherapy of bone cancer are commonly used in the treatment of bone tumor,but it is still highly challenging to prevent recurrence and fill the bone defect caused by the resection site.In this work,we report a rational integration of photonic-responsive two-dimensional(2D)ultrathin niobium carbide(Nb2C)MXene nanosheets(NSs)into the 3D-printed bone-mimetic scaffolds(NBGS)for osteosarcoma treatment.The integrated 2D Nb2C-MXene NSs feature specific photonic response in the second near-infrared(NIR-II)biowindow with high tissue-penetrating depth,making it highly efficient in killing bone cancer cells.Importantly,Nb-based species released by the biodegradation of Nb2C MXene can obviously promote the neogenesis and migration of blood vessels in the defect site,which can transport more oxygen,vitamins and energy around the bone defect for the reparative process,and gather more immune cells around the defect site to accelerate the degradation of NBGS.The degradation of NBGS provides sufficient space for the bone remodeling.Besides,calcium and phosphate released during the degradation of the scaffold can promote the mineralization of new bone tissue.The intrinsic multifunctionality of killing bone tumor cell and promoting angiogenesis and bone regeneration makes the engineered Nb2C MXeneintegrated composite scaffolds a distinctive implanting biomaterial on the efficient treatment of bone tumor. | Junhui Yin Shanshan Pan Xiang Guo Youshui Gao Daoyu Zhu Qianhao Yang Junjie Gao Changqing Zhang Yu Chen | 2021 | Nano-Micro Letters2021，13，2： | 5 |
| 12 | The line emissions and polarization in blazars显示文摘The correlations between broad-line emission,polarization,and core-dominance parameters are investigated for a sample of 148 blazars(BL Lacertae objects-BLs and flat spectrum radio quasars-FSRQs). An anti-correlation between the broad-line luminosity and the linear polarization is found. The broad-line and polarization relation can be explained by using a relativistic beaming model,which perhaps suggests that BL Lacs and FSRQs are a single class. We also investigated the relation between the ratio of the broad-line luminosity to the Eddington luminosity and linear polarization,and that between the ratio of the broad-line luminosity to the Eddington luminosity and the core-dominance parameter. | YANG JiangHe 1,2 ,FAN JunHui 2,3 & YANG RuShu 1 1 Department of Physics and Electronics Science,Hunan University of Arts and Science,Changde 415000,China 2 Center for Astrophysics,Guangzhou University,Guangzhou 510405,China 3 Key Laboratory of Astronomy Observation and Technology,Guangzhou University,Guangzhou 510405,China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，6： | 4 |
| 13 | Preparation of birnessite-supported Pt nanoparticles and their application in catalytic oxidation of formaldehyde显示文摘Flaky and nanospherical birnessite and birnessite-supported Pt catalysts were successfully prepared and characterized by means of Xray diffraction (XRD),transmission electron microscopy (TEM),energy dispersive spectroscopy (EDS) and N2 adsorption-desorption.Effects of the birnessite morphology and Pt reduction method on the catalytic activity for the complete oxidation of formaldehyde (HCHO) were investigated.It was found that flaky birnessite exhibited higher catalytic activity than nanospherical birnessite.The promoting effect of Pt on the birnessite catalyst indicated that the reduction method of the Pt precursor greatly influenced the catalytic performance.Flaky birnessite-supported Pt nanoparticles reduced by KBH 4 showed the highest catalytic activity and could completely oxidize HCHO into CO2 and H2O at 50℃,whereas the sample reduced using H2-plasma showed lower activity for HCHO oxidation.The differences in catalytic activity of these materials were jointly attributed to the effects of pore structure,surface active sites exposed to HCHO and the dispersion of Pt nanoparticles. | Linlin Liu Hua Tian Junhui He Donghui Wang Qiaowen Yang | 2012 | Journal of Environmental Sciences2012，24，6： | 4 |
| 14 | Analysis of humidity-dependent adhesion between a probe tip and a surface显示文摘 | Li Yang Junhui Hu Huapeng Xiao Wenwen Quan | 2017 | Particuology2017，15，4： | 4 |
| 15 | Principle and Experimental Verification of Novel Dual Driving Face Rotary Ultrasonic Motor显示文摘Existing rotary ultrasonic motors operating in extreme environments cannot meet the requirements of good environmental adaptability and compact structure at same time,and existing ultrasonic motors with Langevin transducers show better environmental adaptability,but size of these motors are usually big due to the radial arrangement of the Langevin transducers.A novel dual driving face rotary ultrasonic motor is proposed,and its working principle is experimentally verified.The working principle of the novel ultrasonic motor is firstly proposed.The 5th in-plane flexural vibration travelling wave,excited by the Langevin transducers around the stator ring,is used to drive the rotors.Then the finite element method is used in the determination of dimensions of the prototype motor,and the confirmation of its working principle.After that,a laser Doppler vibrometer system is used for measuring the resonance frequency and vibration amplitude of the stator.At last,output characteristics of the prototype motor are measured,environmental adaptability is tested and performance for driving a metal ball is also investigated.At room temperature and 200 V(zero to peak) driving voltage,the motor's no-load speed is 80 r/min,the stalling torque is 0.35 N·m and the maximum output power is 0.85 W.The response time of this motor is 0.96 ms at the room temperature,and it decreases or increases little in cold environment.A metal ball driven by the motor can rotate at 210 r/min with the driving voltage 300 V(zero to peak).Results indicate that the prototype motor has a large output torque and good environmental adaptability.A rotary ultrasonic motor owning compact structure and good environmental adaptability is proposed,and lays the foundations of ultrasonic motors' applications in extreme environments. | LU Xiaolong HU Junhui YANG Lin ZHAO Chunsheng | 2013 | Chinese Journal of Mechanical Engineering2013，26，5： | 4 |
| 16 | Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay显示文摘Optical-resolution photoacoustic microscopy(OR-PAM)has demonstrated high-spatial-resolution imaging of optical absorption in biological tissue.To date,most OR-PAM systems rely on mechanical scanning with confocally aligned optical excitation and ultrasonic detection,limiting the wide-field imaging speed of these systems.Although several multifocal OR-PA(MFOR-PA)systems have attempted to address this limitation,they are hindered by the complex design in a constrained physical space.Here,we present a two-dimensional(2D)MFOR-PAM system that utilizes a 2D microlens array and an acoustic ergodic relay.Using a single-element ultrasonic transducer,this system can detect PA signals generated from 400 optical foci in parallel and then raster scan the optical foci patterns to form an MFOR-PAM image.This system improves the imaging resolution of an acoustic ergodic relay system from 220 to 13μm and enables 400-folds shorter scanning time than that of a conventional OR-PAM system at the same resolution and laser repetition rate.We demonstrated the imaging ability of the system with both in vitro and in vivo experiments. | Yang Li Terence T.W.Wong Junhui Shi Hsun-Chia Hsu Lihong V.Wang | 2020 | Light(Science & Applications)2020，9，1： | 4 |
| 17 | The gamma-ray spectral index changes for blazars显示文摘Based upon Fermi 1FGL and EGRET 3EG samples,a sample including 79 blazars(53 FSRQs,26 BL Lacs) is presented.It is investigated that the correlations between the ratio of EGRET to Fermi blazars-ray flux densities and the spectral index differ for EGRET to Fermi blazars for three subclasses of high-frequency peaked BL Lacertae objects-HBL,low-frequency peaked BL Lacertae objects-LBL,and flat spectrum radio quasars-FSRQs.There is a consistent relationship between the ratio of the two γ-ray flux densities and the spectral index difference for the three subclasses.It suggests that the spectrum changed with the source brightness in the gamma-ray band.Both the spectral index difference and the correlation slopes follow a continuous sequence from FSRQs to LBLs to HBLs,which is consistent with the noted blazar sequence. | YANG JiangHe FAN JunHui NIE JianJun YANG RuShu | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，11： | 3 |
| 18 | Electropolishing of titanium alloy under hydrodynamic mode显示文摘Titanium(Ti) alloys are widely used in aerospace industry due to the low density and high corrosion resistance. However, machining and polishing remain great challenges because of the hardness and chemical stability. With a home-made electrochemical machining workstation, cyclic voltammetry is performed at a wide potential range of [0 V, 20 V] to record the details of passivation and depassivation processes under a hydrodynamic mode. The results show that the thickness of viscous layer formed on the alloy surface plays a crucial effect on the electropolishing quality. The technical parameters, including the mechanical motion rate, polishing time and electrode gap, are optimized to achieve a surface roughness less than 1.9 nm, which shows a prospective application in the electrochemical machining of Ti and it alloys. | Pei Huang Junhui Lai Lianhuan Han Fang-Zu Yang Li-Min Jiang Jian-Jia Su Zhao-Wu Tian Zhong-Qun Tian Dongping Zhan | 2016 | Science China Chemistry2016，59，11： | 3 |
| 19 | Hydrophilic modification of poly(aryl sulfone) membrane materials toward highly-efficient environmental remediation显示文摘Poly(aryl sulfone)as a typical membrane material has been widely used due to excellent mechanical,chemical and thermal stability.However,the inherent hydrophobicity of poly(aryl sulfone)based membranes bears with the fouling issue during applications,which makes the membrane tending to adsorb contaminants on the surface so as to result in decreased separation performance and lifetime.In this critical review,we give a comprehensive overview on characterizations of hydrophilic membrane and diverse hydrophilic modification approaches of poly(aryl sulfone)membranes,predominantly including bulky,blending and surface modification technology.The discussions on the different modification methods have been provided in-depth.Besides,focusing on modification methods and performance of modified membranes,the related mechanisms for the performance enhancement are discussed too.At last,the perspectives are provided to guide the future directions to develop novel technology to manipulate the hydrophilicity of poly(aryl sulfone)membranes toward diverse practical and multifunctional applications. | Fan Yang Junhui Huang Lijun Deng Yanqiu Zhang Guodong Dang Lu Shao | 2022 | Frontiers of Chemical Science and Engineering2022，16，5： | 3 |
| 20 | Enhancing phosphorus uptake efficiency through QTL-based selection for root system architecture in maize显示文摘Root system architecture(RSA) plays an important role in phosphorus(P) acquisition,but enhancing P use efficiency(PUE) in maize via genetic manipulation of RSA has not yet been reported.Here,using a maize recombinant inbred line(RIL) population,we investigated the genetic relationships between PUE and RSA,and developed P-efficient lines by selection of quantitative trait loci(QTLs) that coincide for both traits.In low-P(LP) fields,P uptake efficiency(Pup E) was more closely correlated with PUE(r =0.48-0.54),and RSA in hydroponics was significantly related to Pup E(r=0.25-0.30) but not to P utilization efficiency(Put E).QTL analysis detected a chromosome region where two QTLs for PUE,three for Pup E and three for RSA were assigned into two QTL clusters,Cl-bin3.04 a and Cl-bin3.04 b.These QTLs had favorable effects from alleles derived from the large-rooted and high-Pup E parent.Marker-assisted selection(MAS) identified nine advanced backcross-derived lines carrying Cl-bin3.04 a or Cl-bin3.04 b that displayed mean increases of 22%e26% in PUE in LP fields.Furthermore,a line L224 pyramiding Clbin3.04 a and Cl-bin3.04 b showed enhanced Pup E,relying mainly on changes in root morphology,rather than root physiology,under both hydroponic and field conditions.These results highlight the physiological and genetic contributions of RSA to maize Pup E,and provide a successful study case of developing P-efficient crops through QTL-based selection. | Riliang Gu Fanjun Chen Lizhi Long Hongguang Cai Zhigang Liu Jiabo Yang Lifeng Wang Huiyong Li Junhui Li Wenxin Liu Guohua Mi Fusuo Zhang Lixing Yuan | 2016 | Journal of Genetics and Genomics2016，43，11： | 3 |
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