|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long-term survival after resection of pancreatic cancer:A single-center retrospective analysis显示文摘AIM: To retrospectively analyze factors affecting the long-term survival of patients with pancreatic cancer who underwent pancreatic resection.METHODS: From January 2000 to December 2011,195 patients underwent pancreatic resection in our hospital.The prognostic factors after pancreatic resection were analyzed in all 195 patients.After excluding the censored cases within an observational period,the clinicopathological characteristics of 20 patients who survived ≥ 5(n = 20) and < 5(n = 76) years were compared.For this comparison,we analyzed the patients who underwent surgery before June 2008 and were observed for more than 5 years.For statistical analyses,the log-rank test was used to compare the cumulative survival rates,and the χ2 and Mann-Whitney tests were used to compare the two groups.The CoxHazard model was used for a multivariate analysis,and P values less than 0.05 were considered significant.A multivariate analysis was conducted on the factors that were significant in the univariate analysis.RESULTS: The median survival for all patients was 27.1 months,and the 5-year actuarial survival rate was 34.5%.The median observational period was 595 d.With the univariate analysis,the UICC stage was significantly associated with survival time,and the CA19-9 ≤ 200 U/m L,DUPAN-2 ≤ 180 U/m L,t u m o r s i ze ≤ 2 0 m m,R 0 re s e c t i o n,a b s e n c e o f lymph node metastasis,absence of extrapancreatic neural invasion,and absence of portal invasion were favorable prognostic factors.The multivariate analysis showed that tumor size ≤ 20 mm(HR = 0.40; 95%CI: 0.17-0.83,P = 0.012) and negative surgical margins(R0 resection)(HR = 0.48; 95%CI: 0.30-0.77,P = 0.003) were independent favorable prognostic factors.Among the 96 patients,20 patients survived for 5 years or more,and 76 patients died within 5 years after operation.Comparison of the 20 5-year survivors with the 76 non-survivors showed that lower concentrations of DUPAN-2(79.5 vs 312.5 U/mL,P = 0.032),tumor size ≤ 20 mm(35% vs 8%,P = 0.008),R0 resection(95% vs 61%,P = 0.004),and absence of lymph nodemetastases(60% vs 18%,P = 0.036) were significantly associated with the 5-year survival.CONCLUSION: Negative surgical margins and a tumor size ≤ 20 mm were independent favorable prognostic factors.Histologically curative resection and early tumor detection are important factors in achieving long-term survival. | Takehito Yamamoto Shintaro Yagi Hiromitsu Kinoshita Yusuke Sakamoto Kazuyuki Okada Kenji Uryuhara Takeshi Morimoto Satoshi Kaihara Ryo Hosotani | 2015 | World Journal of Gastroenterology2015，21，1： | 18 |
| 2 | Silicon micromachining to tissue engineer branched vascular channels for liver fabrication 显示文摘 | Borenstein J Koka R | 2000 | Tissue Eng2000，6，2： | 1 |
| 3 | Simultaneous determination of azimsulfuron, flazasulfuron and halosulfuronmethyl in grains, seeds, vegetables and fruits by HPLC 显示文摘 | ISHIMITSU S KAIHARA A YOSHII K | 2002 | Jouranl of Health Science2002，48，4： | 1 |
| 4 | Multi-agent based supply chain modeling with dynamic environment显示文摘 | TOSHIYA KAIHARA | 2003 | International Journal of Production Economics2003，85，2： | 1 |
| 5 | Development of mitsubishi 'I'powertrain显示文摘 | Higashi H Kaihara K Miyamoto H | 2004 | Mitsubishi Motors Technical Review2004，，16： | 1 |
| 6 | Redifferentiation and decreased expression of adhesion molecules, E-eadherin and ZO-1 in colorectal cancer are closely related to liver metastasis 显示文摘 | Kaihara T Kusaka T Nishi M | 2003 | J Exp Clin Cancer Res2003，22，1： | 1 |
| 7 | Living donor liver transplantation with monosegments 显示文摘 | Kasahara M Kaihara S Oike F | 2003 | Transplantation2003，76，： | 1 |
| 8 | Influence of parents'oral health behaviour on oral health status of their school children:an exploratory study employing a causal modelling technique显示文摘 | Okada M Kawamura M Kaihara Y | 2002 | Int J Paediatr Dent2002，12，2： | 1 |
| 9 | Anatomical variations and surgical strategies in right lobe living donor liver transplantation: lessons from 120 cases1显示文摘 | Taro Nakamura Koichi Tanaka Tetsuya Kiuchi Mureo Kasahara Fumitaka Oike Mikiko Ueda Satoshi Kaihara Hiroto Egawa Ilgin Ozden Nobuaki Kobayashi Shinji Uemoto | 2002 | Transplantation2002，，12： | 1 |
| 10 | Redifferentiation and ZO-1 reexprcssion in liver-metastasized colorectal cancer: possible association with epidermal growth factor receptor-induced tyrosine phosphorylation of ZO-1 显示文摘 | Kaihara T Kawamata H Irnura J | 2003 | Cancer Sci2003，94，2： | 1 |
| 11 | Living donor liver transplantation显示文摘 | Tanaka K Kaihara S | 2003 | Chirurg2003，74，10： | 1 |
| 12 | Olme- sartan and temoeapril prevented the development of hypergly- cemia and the deterioration of pancreatic islet morphology in Otsuka- Long- Evans- Tokushima Fatty rats 显示文摘 | KAIHARA M NAKAMURA Y SUGOMOTO T | 2009 | Acta Med Okayama2009，63，1： | 1 |
| 13 | BACKGROUND AND CLINICAL IMPACT OF TISSUE CONGESTION IN RIGHT-LOBE LIVING-DONOR LIVER GRAFTS: A MAGNETIC RESONANCE IMAGING STUDY显示文摘 | Hidekazu Yamamoto Yoji Maetani Tetsuya Kiuchi Takashi Ito Satoshi Kaihara Hiroto Egawa Kyo Itoh Yasuo Kamiyama Koichi Tanaka | 2003 | Transplantation2003，，1： | 1 |
| 14 | 可变涡流进气系统及其对柴油机性能和排放的影响[J]显示文摘 | SHIMADAKT SAKAI KAIHARA | 1987 | 车用发动机1987，，6： | 1 |
| 15 | Development of mitsubishi ‘‘i,,powertrain 显示文摘 | HIGASHI H KAIHARA K MIYAMOTO H | 2004 | MitsubishiMotors Technical Review2004，，16： | 1 |
| 16 | Development of mitsubishi 'i' powertrain显示文摘 | Hirofumi Higashi Kuniaki Kaihara Hideki Miyamoto | 2004 | Mitsubishi Motors Technical Review2004，，16： | 1 |
| 17 | Simultaneous Determination of Residues of Emamectin and Its Metabolites,and Milbemectin, Ivermectin, and Abamectin in Crops by Liquid Chromatography with Fluorescence Detection显示文摘 | YOSHII K KAIHARA A TSUMURA Y | 2001 | Journal of AOAC International2001，84，3： | 1 |
| 18 | Influence of parents'oral health behavior on oral health status of their school children: an exploratory study employing a caus- al modeling technique显示文摘 | Okada M Kawamura M Kaihara Y | 2002 | Int J Paediatr Dent2002，12，： | 1 |
| 19 | Practical efficacy of telmisartan for decreasing morning home blood pressure and pulse wave velocity in patients with mild-to-moderate hypertension 显示文摘 | Uchida H Nakamura Y Kaihara M | 2004 | Hypertens Res2004，27，： | 1 |
| 20 | Contribution of Waste to Energy Technology to Global Warming显示文摘 | Takuma M Kaihara Y Yamada A | 2004 | Tech Rev2004，41，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员