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| 1 | Irritable bowel syndrome: A microbiome-gut-brain axis disorder?显示文摘Irritable bowel syndrome(IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a suitable model for the disorder. The gut microbiome may play an important role in the onset and exacerbation of symptoms in the disorder and has been extensively studied in this context. Although a causal role cannot yet be inferred from the clinical studies which have attempted to characterise the gut microbiota in IBS, they do confirm alterations in both community stability and diversity. Moreover, it has been reliably demonstrated that manipulation of the microbiota can influence the key symptoms, including abdominal pain and bowel habit, and other prominent features of IBS. A variety of strategies have been taken to study these interactions, including probiotics, antibiotics, faecal transplantations and the use of germ-free animals. There are clear mechanisms through which the microbiota can produce these effects, both humoral and neural. Taken together, these findings firmly establish the microbiota as a critical node in the gut-brain axis and one which is amenable to therapeutic interventions. | Paul J Kennedy John F Cryan Timothy G Dinan Gerard Clarke | 2014 | World Journal of Gastroenterology2014,20,39: | 20 |
| 2 | 多种形式促动医患协作 营造自下而上的患者安全文化显示文摘通过对国内外医患关系和患者安全文化的现状进行梳理,明晰推广患者安全文化的必要性和紧迫性,着重介绍澳大利亚新南威尔士州为促进患者安全发起的患者合作、临床领导力改善等重点项目,以期为我国创建患者安全文化拓宽思路,提供借鉴和启示。Promote patient partnering and the bottom-to-top patient safety culture in various forms/SUN Dongyue,SUN Niuyun,Clifford F Hughes,et al//Chinese Hospitals.-2012,16(10) | 孙冬悦 孙纽云 Clifford F Hughes Peter Kennedy | 2012 | 中国医院2012,16,10: | 3 |
| 3 | 逐步推动政府主导、多方协作的患者安全管理保障体系建设显示文摘在系统介绍澳大利亚新南威尔士州卫生行政部门机构沿革和职能转变的基础上,着重从法律法规建立、法定卫生组织支撑、支付筹资手段改革、信息系统设计、专项措施和评估手段、安全文化建设等6个方面分析了其患者安全与质量管理体系的构建过程,为我国患者安全和质量管理体系建立和完善提供参考和建议。 | 孙纽云 房珊杉 Clifford F Hughes Peter Kennedy | 2012 | 中国医院2012,16,10: | 2 |
| 4 | The American Red Cross Donor Hemovigilance Program, complications of donation显示文摘 | Eder A F Dy B A Kennedy J A | 2006 | Transfusion2006,46,9: | 1 |
| 5 | Neurogenesis and commitment of corticospinal neurons in reeler显示文摘 | Polleux F Dehay C Kennedy H | 1998 | J Neurosci1998,18,: | 1 |
| 6 | Leaf surface chemicals from Nicotiana affecting germination of Peronospora tabacina (Adam) sporangia 显示文摘 | Kennedy B S Nielsen M T Severson R F | 1992 | J Chem Ecol1992,18,: | 1 |
| 7 | Symplectic analysis of vertical random vibration for coupled vehicle- track systems显示文摘 | LU F KENNEDY D WILLIAMS F W | 2008 | Journal of Sound and Vibration2008,317,12: | 1 |
| 8 | Characters of rice starch gel modified by gellan, carrageenan, and glueomannan: A texture profile analysis study显示文摘 | Huang M Kennedy J F Li B | 2007 | Carbohydrate Polymers2007,69,3: | 1 |
| 9 | A temporal link between the Emeishan large igneous province (SW China) and the end-Guagalupian mass extinction 显示文摘 | Zhou M F Malpas J Song X Y Robinson P T Sun M Kennedy A K Lesher C M Keays R R | 2002 | Earth arut Planetary Science Letters2002,196,: | 1 |
| 10 | Porcine circovirus infection in Northern Ireland显示文摘 | KENNEDY S ALLAN G MCNEILLY F | 1998 | Vet Rec1998,142,: | 1 |
| 11 | SHRIMP U - Pb zircon geochronological and geochemical evidence for Neoproterozoic arc-magmatism along the western margin of the Yangtze Block, South China 显示文摘 | Zhou M F Yan D P Kennedy A K | 2002 | Earth and Planetary Science Letters2002,196,1: | 1 |
| 12 | The ap- plication of NMR to study changes in polar metabolite concentrations in beef longissimus dorsi stored for differ- ent periods post mortem 显示文摘 | Graham S F Kennedy T Chevallier O | 2010 | Metabolomics2010,6,3: | 1 |
| 13 | Retention and transport of nutrients in a third-order stream in northwestern California: hyporheic processes 显示文摘 | Triska F J Kennedy V C Avanzino R J | 1989 | Ecology1989,70,6: | 1 |
| 14 | Porcine circovirus infection in Northern Ireland 显示文摘 | Kennedy S Allan G McNeilly F | 1998 | Veterinary Record1998,142,18: | 1 |
| 15 | Evaluation of floating treatment wetlands as retrofits to existing stormwater re- tention ponds 显示文摘 | WINSTON R J HUNT W F KENNEDY S G | 2013 | Ecological Engineering2013,54,: | 1 |
| 16 | Metal complexation by chitosan and its derivatives:a review显示文摘 | Varma A J Deshpande S V Kennedy J F | 2004 | Carbohydrate Polymers2004,55,: | 1 |
| 17 | Ecological, agricultural, genetic, and commercial considerations in the deployment of insect-resistant germplasm显示文摘 | Kennedy G G Gould F Deponti O M B | 1987 | Environmental Entomology1987,16,2: | 1 |
| 18 | Sliding wear mechanism of polytetrafluoroethylene ( PTFE ) and PTFE composites 显示文摘 | T A Blanchet F E Kennedy | 1992 | Wear1992,153,: | 1 |
| 19 | Shrimp zircon geochronological and geochemical evidence for Neo - Proterozoic arc - related magmatism along the western of the Yangtze Block, South China 显示文摘 | Zhou M F Yah D P Kennedy A K Li Q I and Ding J | 2002 | Earth Planet Sci Lett2002,196,: | 1 |
| 20 | SHRIMP U-Pb zircon geochronological and geochemical evidence for Neoproterozoic arcmagmatism along the western margin of the Yangtze Block, South China显示文摘 | Zhou M F Yan D P Kennedy A K | 2002 | Earth Planet Sci Lett2002,196,: | 1 |