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| 1 | High-intensity focused ultrasound ablation:An effective bridging therapy for hepatocellular carcinoma patients显示文摘AIM:To analyze whether high-intensity focused ultrasound(HIFU) ablation is an effective bridging therapy for patients with hepatocellular carcinoma(HCC).METHODS:From January 2007 to December 2010,49 consecutive HCC patients were listed for liver transplantation(UCSF criteria).The median waiting time for transplantation was 9.5 mo.Twenty-nine patients received transarterial chemoembolization(TACE) as a bringing therapy and 16 patients received no treatment before transplantation.Five patients received HIFU ablation as a bridging therapy.Another five patients with the same tumor staging(within the UCSF criteria) who received HIFU ablation but not on the transplant list were included for comparison.Patients were comparable in terms of Child-Pugh and model for end-stage liver disease scores,tumor size and number,and cause of cirrhosis.RESULTS:The HIFU group and TACE group showed no difference in terms of tumor size and tumor number.One patient in the HIFU group and no patient in the TACE group had gross ascites.The median hospital stay was 1 d(range,1-21 d) in the TACE group and two days(range,1-9 d) in the HIFU group(P < 0.000).No HIFU-related complication occurred.In the HIFU group,nine patients(90%) had complete response and one patient(10%) had partial response to the treatment.In the TACE group,only one patient(3%) had response to the treatment while 14 patients(48%) had stable disease and 14 patients(48%) had progressive disease(P = 0.00).Seven patients in the TACE group and no patient in the HIFU group dropped out from the transplant waiting list(P = 0.559).CONCLUSION:HIFU ablation is safe and effective in the treatment of HCC for patients with advanced cirrhosis.It may reduce the drop-out rate of liver transplant candidate. | Tan To Cheung Sheung Tat Fan See Ching Chan Kenneth SH Chok Ferdinand SK Chu Caroline R Jenkins Regina CL Lo James YY Fung Albert CY Chan William W Sharr Simon HY Tsang Wing Chiu Dai Ronnie TP Poon Chung Mau Lo | 2013 | World Journal of Gastroenterology2013，19，20： | 23 |
| 2 | Characteristics, covariances, andaverage returns: 1929-1997显示文摘 | Davis James L Eugene F Fama and Kenneth R | 2000 | Journal of Finance2000，55，： | 1 |
| 3 | Hot blast stove process model and model-based controller显示文摘 | Kenneth R Muske James W Howse Glen A Hansen | 1999 | Iron and Steel Engineer1999，76，6： | 1 |
| 4 | Hot blast stove process model and model-based controller显示文摘 | Muske Kenneth R Howse James W Hansen Glen A | 1999 | Iron and Steel Engineer1999，76，6： | 1 |
| 5 | Practical guide to the diagnosis of thalassemia显示文摘 | Kenneth WD Boehm C James R | 1996 | Am J M Genetics1996，62，： | 1 |
| 6 | Practical guide to the di- agnosis of thalassemia显示文摘 | Kenneth WD Boehm C James R | 1996 | Am J M Genetics1996，62，1： | 1 |
| 7 | Physical Activi- ty and dimensions of subjective well-being in older a-dults显示文摘 | Aprodite S Kenneth R F James Mck | 2002 | Journal of Aging and Physical Activity2002，10，： | 1 |
| 8 | Atrial natriuretic factor release is enhanced by incremental atrial pacing显示文摘 | Pramod K James R | 1998 | Am Heart J1998，116，： | 1 |
| 9 | Atrial natriuretic factor release is enhanced by incremental atrial pacing显示文摘 | Kenneth A Pramod K James R | 1998 | Am Heart J1998，116，： | 1 |
| 10 | Investor Diversification and International Equity Markets 显示文摘 | Kenneth R French James M Poterba | 1991 | the American Economic Review1991，81，2： | 1 |
| 11 | Discovery of novel 2-aminobenzamide inhibitors of heat shock pro- tein 90 as potent, selective and orally active antitumor agents 显示文摘 | Kenneth H Huang James M Veal R | 2009 | J Med Chem2009，52，： | 1 |
| 12 | The stability of constrained receding horizon control显示文摘 | B Rawlings James R Muske Kenneth | 1993 | IEEE TRANSACTIONS ON AUTOMATIC CONTROL1993，38，10： | 1 |
| 13 | Predicting reflectance functions form complex surfaces显示文摘 | Stephen H Westin James R Arvo Kenneth E Torrance | 1992 | Computer Graphics1992，26，2： | 1 |
| 14 | Physical activity and dimensions of subjective well-being in older adults 显示文摘 | Aphrodite S Kenneth R F James McK | 2002 | Journal of Aging and Physical Activity2002，10，： | 1 |
| 15 | Discovery of novel 2-aminobenzamide inhibitors of heat shock protein 90 as potent, selective and orally active antitumor agents 显示文摘 | Kenneth H Huang James M Veal R | 2009 | J Med Chem2009，52，： | 1 |
| 16 | Atrial Natriuretic factor release is enhanced by incremental atrial pacing 显示文摘 | Pramod K James R | 1998 | Am Heart J1998，116，： | 1 |
| 17 | Practical guide to the diagnosis of thala ssemia显示文摘 | Kenneth WD Boehm C James R | 1996 | Am J M Genetics1996，62，： | 1 |
| 18 | Nkx2-5 Pathways and Congenital Heart Disease显示文摘 | Mohammad Pashmforoush Jonathan T Lu Hanying Chen Tara St Amand Richard Kondo Sylvain Pradervand Sylvia M Evans Bob Clark James R Feramisco Wayne Giles Siew Yen Ho D.Woodrow Benson Michael Silberbach Weinian Shou Kenneth R Chien | 2004 | Cell2004，，： | 1 |
| 19 | Characteristics,covariances,andaverage returns:1929-1997显示文摘 | Davis James L Eugene F Fama Kenneth R French | 2005 | Journal of Finance2005，5，： | 1 |
| 20 | Infiltration and wetting of alumina particulate performs by aluminum and aluminum-magnesium alloys 显示文摘 | Tamala R Jonas James A Cornie Kenneth C Russell | 1995 | Metall Mater Trans A1995，26，： | 1 |
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