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| 1 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014，6，10： | 6 |
| 2 | Assessment of intake from the diet显示文摘 | R Kroes D Müller J Lambe M.R.H L?wik J van Klaveren J Kleiner R Massey S Mayer I Urieta P Verger A Visconti | 2002 | Food and Chemical Toxicology2002，，2： | 1 |
| 3 | Sulfur emissions to the atmosphere from natural sources显示文摘 | Bate T S Lamb B K Guenther A | 1992 | Journal of Atmospheric Chemistry1992，14，： | 1 |
| 4 | The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver 显示文摘 | Eyal S Lamb J G Smith-Yockman M | 2006 | Br J Pharmacol2006，149，3： | 1 |
| 5 | Application of perfluoropolyether reverse micelles in supercritical CO2 to dyeing process显示文摘 | Saukaran P Lamb D | 1996 | Respir Med1996，90，3： | 1 |
| 6 | A novel Pd/MgAlOx catalyst for NOX storage-reduction显示文摘 | SILLETTI B A ADAMS R T SIGMON S M NIKOLOPOULOS A SPIVEY J J LAMB H H | 2006 | Catal Today2006，114，1： | 1 |
| 7 | Trends in the use and capacity of California's emergency departments, 1990- 1999显示文摘 | Lambe S Washington DL Fink A | 2002 | Ann Emerg Med2002，39，4： | 1 |
| 8 | Alliance competence,resources,and alliance success:Conceptualization,measurement,and initial test显示文摘 | LAMBE C J SPEKMAN R E HUNT S D | 2002 | Academy of Marketing Science2002，30，2： | 1 |
| 9 | Alliance Competence, Resources, and Alliance Success: Conceptualization, Measurement, and Initial Test显示文摘 | Lambe C J Spekman R E Hunt S D | 2002 | Journal of the Academy of Marketing Science2002，30，2： | 1 |
| 10 | Flagellate erythema induced by docetaxel 显示文摘 | Tallon B Lamb S | 2008 | Clin Exp Dermatol2008，33，3： | 1 |
| 11 | Heritability of crown trait in alfalfa显示文摘 | Marquez-Ortiz J J Lamb F S Johnson L D | 1999 | Crop Science1999，39，1： | 1 |
| 12 | Behavior of the brittle crust in wide plate boundary zones显示文摘 | Lamb S | 1994 | Journal of Geophysical Research1994，99，1： | 1 |
| 13 | Whole-genome microar- ray analysisin prenatal specimens identifies clinically significant ebromosomealterations without increase in results of unclear signifi- cance compared totargeted microarray 显示文摘 | Coppinger J Alliman S Lamb AN | 2009 | Prenat Diagn2009，29，12： | 1 |
| 14 | High-frequency oscillation for acute respiratory distress syndrome 显示文摘 | Young D Lamb SE Shah S | 2013 | N Engl J Med2013，368，9： | 1 |
| 15 | Cryopreservation of embryos and ova显示文摘 | Friedler S Giudice L C Lamb E J | 1988 | Fertil Sertil1988，49，： | 1 |
| 16 | Tetratrieopeptide repeat interactions:to TPR or not to TPR?显示文摘 | Lamb J R Tugendreich S Hieter P | 1995 | Trends Biochem Sci1995，20，： | 1 |
| 17 | Alliance compe tence, resources, and alliance success: Conceptualization, measurement, and initial test显示文摘 | Lambe C J Spekman R E Hunt S D | 2002 | Journal of the Academy Of Marketing Science2002，30，2： | 1 |
| 18 | Zopiclone, An update of its pharmacology, clinical efficacy and tolerability in the treatment of insomnia显示文摘 | NOBLE S LANGTRY HD LAMB HM | 1998 | Drugs1998，55，2： | 1 |
| 19 | Sulfur emissions to the atmosphere from natural sources显示文摘 | BATES T S LAMB B K GUENTHER A | 1992 | Journal of Atmospheric Chemistry1992，14，14： | 1 |
| 20 | Correlation between ultrasound characteristics, mammographic findings and histological grade in patients with invasive ductal carcinoma of the breast显示文摘 | LAMB P M PERRY N M VINNICOMBE S J | 2000 | Clin Radiol2000，55，1： | 1 |
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