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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | Twenty-five years of research on the effects of exercise training in breast cancer survivors:A systematic review of the literature显示文摘AIM:To investigate the role of exercise training the past 25 years on major physiological-psychological outcomes studied thus far in this patient population.METHODS:Pub Med, Medline Plus, the Cochrane Library, Web of Science, SportD iscus, Embase, Scorpus, and Google Scholar were searched from September to November 2013 to identify exercise training studies that used objective measurements of fitness and/or patient reported outcomes assessed pre and post-exercise training with statistical analyses performed in at least one of the following outcome measurements:Cardiorespiratory function, body composition, muscular strength, fatigue, depression, and overall quality of life. Five reviewers independently identified the studies that met the criteria for the review and discrepancies were resolved by consensus among all authors.RESULTS:Fifty-one studies were included in this review with 5 from the period between 1989-1999, 11 from 2000-2006, and 35 from 2007-2013. The evolution of study designs changed from aerobic only exercise training interventions(1989-1999), to a combination of aerobic and resistance training(2000-2006), to studies including an arm of resistance training or examining the effects of resistance training as the main mode of exercise(2007-2013). Overall, the benefits of exercise showed improvements in cardiorespiratory function, body composition, strength, and patient reported outcomes including fatigue, depression, and quality of life.CONCLUSION:Exercise training appears to be safe for most breast cancer patients and improvements in physiological, psychological, and functional parameters can be attained with regular participation in moderate intensity exercise. | Claudio L Battaglini Robert C Mills Brett L Phillips Jordan T Lee Christina E Story Marcelo GB Nascimento Anthony Carl Hackney | 2014 | World Journal of Clinical Oncology2014，5，2： | 3 |
| 3 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 4 | Satellite sensor image classification using cascaded architecture of neural fuzzy network显示文摘 | Lin C T Lee Y C Pu P H | 2000 | IEEE Transactions on Geoscience and Remote Sensing2000，38，2： | 2 |
| 5 | 血根碱对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平以及肉品质的影响显示文摘研究旨在探索日粮添加血根碱(SGV)对肉鸡生长性能、相对器官重量、盲肠菌群、血清胆固醇水平和腿肌丙二醛含量的影响。选用840日龄雄性肉鸡(罗斯品种)饲养于28个稻草垫上,随机分为4个处理:玉米-豆粕型基础对照日粮、基础日粮中添加卑霉素10 ppm作为生长促进剂(AGP)、基础日粮中添加SGV 20 ppm(SGV20)和50 ppm(SGV50)。与饲喂基础日粮的肉鸡相比,基础日粮中添加AGP组、SGV20组和SGV50组的肉鸡最终体重(BW)、日增重、饲料转化率(FCR)显著改善(P<0.05)。与对照组相比,SGV20喂养组的肉鸡相对空肠重量显著降低(P<0.05),所有添加SGV组肉鸡相对空肠或回肠长度显著升高(P<0.05)。SGV20组较对照组肉鸡肠道菌群有所改变,尤其是盲肠乳酸菌数增加,但AGP组无改变。SGV20组或SGV50组肉鸡的总胆固醇水平较对照组显著降低(P<0.05),控制饮食物显著降低(P<0.05)。添加SGV后,作为脂质过氧化反应指示剂的腿肌丙二醛含量显著降低(P<0.05)。研究表明,在肉鸡日粮中补充SGV 20或50 ppm可以提高肉鸡生长性能,改变多种生物和生理参数,如相对器官重量、血清胆固醇水平、肠道菌群和肉品质。 | Lee K W Kim J S Oh S T Kang C W An B K | 2015 | 饲料博览2015，0，3： | 2 |
| 6 | A potential based panel method for the analysis of a two-dimensional super or partially cavitating hydrofoil 显示文摘 | LEE C S KIM Y G LEE J T | 1992 | J of Ship Res1992，36，2： | 2 |
| 7 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 8 | 中草药对断奶仔猪中性粒细胞免疫活性和小肠形态学的影响显示文摘试验旨在评估由人参、薯蓣、白术、甘草、红枣和桔梗组成的中草药(CMH)对断奶仔猪生产性能、肠道形态学和免疫活性的影响。将240头断奶仔猪随机分为4个日粮处理组:负对照组(基础日粮),CMH0.1%、CMH0.3%、抗生素0.114%(金霉素钙复合物、磺胺噻唑、青霉素普鲁卡因G)添加组,试验期28d。结果表明,试验期前14d,两个CMH添加组比对照组(CT组)有较佳的增重和饲料增重比。与其他组比较,在试验前10d,CMH0.3%组的腹泻评分显著下降。与对照组比较,CMH添加组有较高的绒毛高度,回肠食糜乳酸菌计数增加,大肠菌群数下降。在试验第7天,CMH添加组的多形核白细胞(PMNs)活性,包括突发性呼吸和沙门氏菌杀灭能力显著提高。添加CMH和抗生素可提高断奶仔猪日粮干物质、粗蛋白质和总能的养分消化率。结果表明,日粮添加CMH可改善肠道形态学和PMNs的免疫活性,因而提高断奶仔猪的养分消化率,降低腹泻频率。 | Huang C W Lee T T Shih Y C Yu B 张树金 | 2012 | 饲料博览2012，，9： | 2 |
| 9 | Adaptive vector quantize using a self-development neural network显示文摘 | Lee T C | 1990 | IEEE Journal on Select Areas in Communications1990，8，10： | 2 |
| 10 | Tracking design of uncertain nonlinear SISO systems:adaptive fuzzy approach显示文摘 | CHEN B S LEE T S CHANG Y C | 1994 | IEEE Transactions on Fuzzy Systems1994，4，2： | 2 |
| 11 | The potential role of resistin in atherogenesis 显示文摘 | BURNETT M S LEE C W KINNAIRD T D | 2005 | Atherosclerosis2005，182，： | 1 |
| 12 | Screw Dislocation Dipole Near an Internal Crack显示文摘 | Lin K M Hu C T Lee S B | 1993 | Engineering Fracture Mechanics1993，45，： | 1 |
| 13 | 显示文摘 | Lee T H Oh C S Lee C G | 2004 | Scripta Materialia2004，5，50： | 1 |
| 14 | Adsorption and diffusion of aromatics in AIPO4-5显示文摘 | CHIANG A S T LEE C K CHANG Z H | 1991 | Zeolites1991，11，4： | 1 |
| 15 | Modeling of fugitive dust emission for construction sand and gravel processing plant显示文摘 | Lee C H Tang L W Chang C T | 2001 | Environmental Science and Technology2001，35，： | 1 |
| 16 | Fiber-to-the-home services based on wavelength-division-multiplexing passive optical network 显示文摘 | PARK S J LEE C H JEONG K T et at | 2004 | Journal of Lightwave Technology2004，22，11： | 1 |
| 17 | Effect of phosphorus dopant on photoluminescence and field-emission characteristics of MgZnO nanowires显示文摘 | Lee C Y Tseng T Y Li S Y | 2006 | J Appl Phys2006，99，24： | 1 |
| 18 | Investigations of pistoneffect and jet fan-effect in model vehicle tunnels 显示文摘 | Chen T Y Lee Y T Hsu C C | 1998 | Journal of Wind Engineering and Industrial Aerodynamics1998，73，2： | 1 |
| 19 | Sliding mode controller for linear systems with mismatched time-varying uncertainties 显示文摘 | TAO C W LEE T T | 2000 | Journal of Franklin Institute2000，337，： | 1 |
| 20 | Characterization and distribution of metals in surficial sediments in Sontheastern Taiwan显示文摘 | Lee C L Fang M D Hsich M T | 1998 | Marine Pollution Bulletin1998，36，6： | 1 |
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