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| 1 | Feasibility study of computed vs measured high b-value(1400 s/mm2) diffusion-weighted MR images of the prostate显示文摘AIM: To evaluate the impact of computed b = 1400 s/mm2(C-b1400) vs measured b = 1400 s/mm2(M-b1400) diffusion-weighted images(DWI) on lesion detection rate, image quality and quality of lesion demarcation using a modern 3T-MR system based on a small-field-of-view sequence(sFOV). METHODS: Thirty patients(PSA: 9.5 ± 8.7 ng/mL; 68 ± 12 years) referred for magnetic resonance imaging(MRI) of the prostate were enrolled in this study. All measurements were performed on a 3T MR system.For DWI, a single-shot EPI diffusion sequence(b = 0, 100, 400, 800 s/mm2) was utilized. C-b1400 was cal-culated voxelwise from the ADC and diffusion images. Additionally, M-b1400 was acquired for evaluation and comparison. Lesion detection rate and maximum lesion diameters were obtained and compared. Image quality and quality of lesion demarcation were rated accord-ing to a 5-point Likert-type scale. Ratios of lesion-to-bladder as well as prostate-to-bladder signal intensity(SI) were calculated to estimate the signal-to-noise-ratio(SNR). RESULTS: Twenty-four lesions were detected on M-b1400 images and compared to C-b1400 images. C-b1400 detected three additional cancer suspicious lesions. Overall image quality was rated significantly better and SI ratios were significantly higher on C-b1400(2.3 ± 0.8 vs 3.1 ± 1.0, P < 0.001; 5.6 ± 1.8 vs 2.8 ± 0.9, P < 0.001). Comparison of lesion size showed no significant differences between C- and M-b1400(P = 0.22). CONCLUSION: Combination of a high b-value extrap-olation and sFOV may contribute to increase diagnostic accuracy of DWI without an increase of acquisition time, which may be useful to guide targeted prostate biopsies and to improve quality of multiparametric MRI(mMRI) especially under economical aspects in a pri-vate practice setting. | Leonardo K Bittencourt Ulrike I Attenberger Daniel Lima Ralph Strecker Andre de Oliveira Stefan O Schoenberg Emerson L Gasparetto Daniel Hausmann | 2014 | World Journal of Radiology2014，6，6： | 5 |
| 2 | The activity of Caspase-3-like proteases is elevated during the development of colorectal carcinorna显示文摘 | Leonardos I Butler LM Hewett PJ | 1999 | Cancer Lett1999，143，1： | 1 |
| 3 | On the apterous line of the termite Velociterts heteropterus ( lsoptera : Termitidae ) : Developmental pathways and cellulose digestion 显示文摘 | Haifig I Leonardo FC Costa FF | 2012 | Zoological Science2012，29，12： | 1 |
| 4 | Speciation of phosphorus fractionation in river sediments by explanatory data analysis显示文摘 | KATSAOUOS C Z GIOKAS D L LEONARDOS I D | 2007 | Water Research2007，41，2： | 1 |
| 5 | Interdependent response of networked systems 显示文摘 | Leonardo D James I Barry J | 2007 | Journal of Infrastructure System2007，，10： | 1 |
| 6 | Copper and zinc in four fresh-water fish species from lake Pamvotis (Greece) 显示文摘 | Papagiannis I Kagalou I Leonardos J | 2004 | Environment International2004，30，： | 1 |
| 7 | Enhanced Power Quality Control Strategy for Single-Phase Inverters in Distributed Generation System显示文摘 | Radu I Leonardo R Daniel R | 2011 | IEEE Transactions on Power Electronics2011，26，3： | 1 |
| 8 | Land surface temperature retrieval from LANDSAT TM 5显示文摘 | SOBRINO J A JIMENEZ-MUNOZ J C LEONARDO P I | 2004 | Remote Sensing of Environment2004，90，： | 1 |
| 9 | Reproducibility of quantitative fiber tracking measurements in diffusion tensor imaging of frontal lobe tracts: A protocol based on the fiber dissection technique显示文摘 | Dini Leandro I Vedolin Leonardo M Bertholdo Debora | 2013 | Surg Ncurol Int2013，58，4： | 1 |
| 10 | Characterization of short chain fatty acid microcapsules produced by spray drying 显示文摘 | Maria I T Leonardo R A Farina M | 2004 | Materials Science and Engineering2004，24，5： | 1 |
| 11 | Net- work Coding and Evolutionary Theory for Per- formance Enhancement in Wireless Cooperative Clusters显示文摘 | LEONARDO M FITZEK F ANTONIO I | 2010 | European Transactions on Telecom- munications2010，21，8： | 1 |
| 12 | Cytokines and cell Adhesion Molecules in Cerebral Isehemia 显示文摘 | Leonardo P Cristina S Domenico I | 1998 | Arteriosclerosis Thrornbosis andVascular Biology1998，18，： | 1 |
| 13 | Learning for sharing:An empirical analysis of organizational learning and knowledge sharing 显示文摘 | LEONARDO I A PABLO E Z S | 2011 | International Entrepreneurship and Management Journal2011，7，4： | 1 |
| 14 | Estimation of primary drainage three-phase relative permeability for organic liquid transport in the vadose zone显示文摘 | Leonardo I Oliveira Avery H Demond | 2003 | Journal of Contaminant Hydrology2003，66，： | 1 |
| 15 | Interdependent response of networked systems显示文摘 | Leonardo Dueas-Osorio James I Craig Barry G Goodno | 2007 | Journal of Infrastructure Systems2007，10，： | 1 |
| 16 | The chemistry of some Brazilian soils: Element mobility during intense weathering显示文摘 | Kronberg B I Fyfe W S Leonardos O H | 1979 | Chemical Geology1979，24，： | 1 |
| 17 | Copper and zinc in four freshwater fish species from Lake Pamvotis(Greece)显示文摘 | Papagiannis I Kagalou I Leonardos J | 2004 | Environmental International2004，30，： | 1 |
| 18 | Reproduction of Mothocya epimerica ( Crustacea: Isopoda: Cymothoidae), parasitic on the sand smelt Atherina boyeri ( Osteichthyes : Atherinidae) in Greek lagoons 显示文摘 | LEONARDOS I TRILLES J P | 2004 | Diseases of Aquatic Organ- isms2004，62，： | 1 |
| 19 | Integrating reasoning and clinical archetypes using OWL ontologies and SWRL rules显示文摘 | Leonardo Lezcano Miguel-Angel Sicilia Carlos Rodr I guez-Solano | 2011 | Journal of Biomedical Informatics2011，44，： | 1 |
| 20 | Assessment of a Mediterranean shallow lentic ecosystem ( Lake Pamvotis, Greece) using benthic community diversity: Response to environmental parameters 显示文摘 | KAGALOU I ECONOMIDIS G LEONARDOS I | 2006 | Linmologica - Ecology and Management of Inland Waters2006，36，4： | 1 |
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