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| 1 | Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma显示文摘 | Ling CQ Li B Zhang C Zhu DZ Huang XQ Gu W Li SX | 2005 | 第二军医大学学报2005,26,10: | 30 |
| 2 | Transjugular intrahepatic portosystemic shunt vs endoscopic therapy in preventing variceal rebleeding显示文摘AIM:To compare early use of transjugular intrahepatic portosystemic shunt(TIPS) with endoscopic treatment(ET) for the prophylaxis of recurrent variceal bleeding.METHODS:In-patient data were collected from 190 patients between January 2007 and June 2010 who suffured from variceal bleeding.Patients who were older than 75 years;previously received surgical treatment or endoscopic therapy for variceal bleeding;and complicated with hepatic encephalopathy or hepatic cancer,were excluded from this research.Thirty-five cases lost to follow-up were also excluded.Retrospective analysis was done in 126 eligible cases.Among them,64 patients received TIPS(TIPS group) while 62 patients received endoscopic therapy(ET group).The relevant data were collected by patient review or telephone calls.The occurrence of rebleeding,hepatic encephalopathy or other complications,survival rateand cost of treatment were compared between the two groups.RESULTS:During the follow-up period(median,20.7 and 18.7 mo in TIPS and ET groups,respectively),rebleeding from any source occurred in 11 patients in the TIPS group as compared with 31 patients in the ET group(Kaplan-Meier analysis and log-rank test,P = 0.000).Rebleeding rates at any time point(6 wk,1 year and 2 year) in the TIPS group were lower than in the ET group(Bonferroni correction α' = α/3).Eight patients in the TIPS group and 16 in the ET group died with the cumulative survival rates of 80.6% and 64.9%(Kaplan-Meier analysis and log-rank test c2 = 4.864,P = 0.02),respectively.There was no significant difference between the two groups with respect to 6-wk survival rates(Bonferroni correction α' = α/3).However,significant differences were observed between the two groups in the 1-year survival rates(92% and 79%) and the 2-year survival rates(89% and 64.9%)(Bonferroni correction α' = α/3).No significant differences were observed between the two treatment groups in the occurrence of hepatic encephalopathy(12 patients in TIPS group and 5 in ET group,KaplanMeier analysis and log-rank test,c2 = 3.103,P = 0.08).The average total cost for the TIPS group was higher than for ET group(Wilcxon-Mann Whitney test,52 678 RMB vs 38 844 RMB,P < 0.05),but hospitalization frequency and hospital stay during follow-up period were lower(Wilcxon-Mann Whitney test,0.4 d vs 1.3 d,P = 0.01;5 d vs 19 d,P < 0.05).CONCLUSION:Early use of TIPS is more effective than endoscopic treatment in preventing variceal rebleeding and improving survival rate,and does not increase occurrence of hepatic encephalopathy. | Hui Xue Meng Zhang Jack XQ Pang Fei Yan Ying-Chao Li Liang-Shan Lv Jia Yuan Muna Palikhe Wei-Zhi Li Zhi-Lun Wang | 2012 | World Journal of Gastroenterology2012,18,48: | 17 |
| 3 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005,4,3: | 10 |
| 4 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005,26,10: | 5 |
| 5 | Orientobilharzia turkestanicum is grouped within African schistosomes based on phylogenetic analysis using sequences of mitochondrial genes 显示文摘 | Li L Yu LY Zhu XQ | 2008 | Parasitol Res2008,102,5: | 1 |
| 6 | Comparison of inhibitory effects of the proton pump-inhibiting drugs Omeprazole, Lansoprazole, Pantoprazole, Esomeprazole and Rabeprazole on human cytochrome P450 activities显示文摘 | Li XQ Andersson TB Weidolf L | 2004 | Drug Metab Dispos2004,32,: | 1 |
| 7 | Nuclear beta-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer显示文摘 | Li XQ Yang XL Zhang G | 2013 | J Transl Med2013,11,: | 1 |
| 8 | Effects and mechanism of down- regulation of survivin expression by RNA interference on prolifera- tion and apoptosis of lung cancer ceils 显示文摘 | Chen XQ Yang S Li ZY | 2012 | Mol Med Report2012,5,4: | 1 |
| 9 | Disease burden of chronic ob-structive pulmonary diseases in west rural areas of China,2004-2005显示文摘 | Shi XQ Hu N Li XY Huang ZJ | 2011 | Zhonghua Yu Fang Yi Xue Za Zhi2011,45,1: | 1 |
| 10 | Diabetic patients with cataract ultrason- ic emulsification iol implantation of clinical observation 显示文摘 | Li XH Pang XQ Zheng R | 2008 | Interna- tional Journal of Ophthalmology2008,,6: | 1 |
| 11 | An evaluation of selfefficacy and satisfaction with the effectiveness of Bu-Fei Yi-Shen Granule combined with acupoint sticking therapy in patients with Chronic Obstructive Pulmonary Disease显示文摘 | Li JS Xie Y Yu XQ | 2013 | Eur J Integr Med2013,5,4: | 1 |
| 12 | Inhibition of T-cell expansion caused by inducible eostimulator/B7h costimulatian blockade in direct alloreeognition pathway 显示文摘 | Du JF Li QY Ji XQ | 2011 | Transplant Proc2011,43,10: | 1 |
| 13 | Belimumab in systemic lupus erythematosus: a perspective review显示文摘 | Hui-Yuen JS Li XQ Askanase AD | 2015 | Ther Adv Musculoskelet Dis2015,7,4: | 1 |
| 14 | Dendritic Cells Induce Specific Cy-totoxic T Lymphocytes against Prostate Cancer TRAMP-C2 CellsLoaded with Freeze-thaw Antigen and PEP-3 Peptide显示文摘 | Liu XQ Jiang R Li SQ | 2015 | AsianPac J Cancer Prev2015,16,2: | 1 |
| 15 | Sertraline protects against monocrotaline induced pulmonary, hypertension in rats 显示文摘 | Li XQ Hong Y Wang Y | 2006 | Clin ExpPharmacol Physiol2006,33,11: | 1 |
| 16 | Differentiation of rat bone marrow stromal ceils into neuron like cells 显示文摘 | LI CQ LIU D WU XQ | 2004 | Zhong Nan Da Xue Xue Bao Yi Xue Ban2004,29,1: | 1 |
| 17 | Inhibition of hydrogen sulfide gen- eration contributes to 1-methy-4-phenylpyridinium ion-induced neu- rotoxicity 显示文摘 | Tang XQ Fan LL Li Y J | 2011 | Neurotox Res2011,19,: | 1 |
| 18 | Serum thymidine kinase 1 is a prognostic and monitoring factor in patients with non-small cell lung cancer显示文摘 | Li HX Lei DS Wang XQ | 2005 | Oncol Rep2005,13,1: | 1 |
| 19 | Computer-assisted orbital volume measurement in the surgical correction of late enophthalmos caused by blowout fractures 显示文摘 | Fan XQ Li J Zhu J | 2003 | Ophthal Plast Reconstr Surg2003,19,3: | 1 |
| 20 | Expression and significance of three types of Fos-immunoreactive cells after gammak nife irradiation of the forebrain in the rat显示文摘 | Duan XQ Wu SL Li T | 1999 | Neurosci Res1999,33,2: | 1 |