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| 1 | A metabonomic investigation on the biochemical perturbation in liver failure patients caused by hepatitis b virus显示文摘 | Yu, K Sheng, GP Sheng, JF Chen, YM Xu, W Liu, XL Cao, HC Qu, HB Cheng, YY Li, LJ | 2007 | 中国生物学文摘2007，21，11： | 25 |
| 2 | Study on the expression of matrix metalloproteinase-2 mRNA in human gastric cancer显示文摘 | Ji F Wang WL Yang ZL Li YM Huang HD Chen WD | 1999 | World Journal of Gastroenterology1999，5，5： | 19 |
| 3 | Effect of extracorporeal bioartificial liver support system on fulminant hepatic failure rabbits显示文摘AIM To evaluate the possibility of usingcultured human hepatocytes as a bridge betweenbioartificial liver and liver transplantation.METHODS In this experiment,the efficacy ofextracorporeal bioartificial liver support system(EBLSS)consisting of spheriodal human livercells and cultured hepatocytes supernatant wasassessed in vivo using galactosamine inducedrabbit model of fulminant hepatic failure.RESULTS There was no difference of survivalbetween the two groups of rabbits,but in thesupported rabbits serum alanineaminotransferase,total bilirubin and creatininewere significantly lower and hepatocyte necrosiswas markedly milder than those in controlanimals.In addition,a good viability of humanliver cells was noted after the experiment.CONCLUSION EBLSS plays a biologic role inmaintaining and compensating the function ofthe liver. | Wang YJ Li MD Wang YM Chen GZ Lu GD Tan ZX | 2000 | World Journal of Gastroenterology2000，6，2： | 17 |
| 4 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 5 | Association of nonalcoholic fatty liver disease with type 2 diabetes: clinical features and independent risk factors in diabetic fatty liver patients显示文摘Nonalcoholic fatty liver disease(NAFLD) is a common chronic liver disease in China, of which diabetic fatty liver (DFL) accounts for a large proportion in clinic. DFL is a disease without specific clinical features and lacking of confirmatory laboratory tests, and the etiology of hepatic steatosis remains poorly understood. The aim of this paper was to explore the clinical characteristics and to determine associated risk factors in type 2 diabetes patients with fatty liver. METHODS: A total of 166 patients, 53 in DFL group and 113 in NDFL(diabetes without fatty liver) group participated in this study. Serum fasting blood glucose (FBG), alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphate (AKP), gamma glutamyl transpeptidase (GGT), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) were measured in both groups. And these variables were analyzed by using Student’ s t test and logistic regression model. RESULTS:A progressive increase in the level of FBG, ALT, AST, AKP, GGT, TG( P<0.05) and a decrease of HDL-C(P<0.01)were observed from DFL group to NDFL group. And there was no statistical difference in the level of TC between the two groups. CONCLUSIONS:Dyslipidemia, dysglycemia and elevation of liver enzyme can be seen more frequently in the DFL patients than in the NDFL patients. The successive escalation of serum ALT and TG levels and the lower HDL-C level are the independent risk factors of DFL. | Department of Digestive Medicine, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Jin HB, Gu ZY, Yu CH and Li YM) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 6 | A novel solid state Michael addition reaction of N-heterocyclic compounds containing active C-H bond显示文摘In this paper,a novel solid state Michael-type addition reaction of N-heterocyclic compounds containing the active-CH group was investigated.3-Methyl-l-phenyl-5-pyrazolone (MPP) and indole (In) reacted with 4-arylmethylene-3-methyl-l-phenyl-5-pyrazolone (1) hi the solid state at room temperature to give the corresponding adducts,aryl-4,4’-bis(5-hydroxy-3-methyl-l-phenyl-pyrazolyl) methane (2a-n) and l-aryl-l-(5’-hydroxy-3’-methyl-1’-phenyl-4’-pyrazolyl)-l-(3'-indolyl) methane (3a-n),respectively.This is a feasible method for preparing the compound which contains two heterocyclic groups on the same carbon. | Li, XL Wang, YM Tian, B Meng, JB | 1996 | Chinese Journal of Chemistry1996，14，5： | 3 |
| 7 | Effet of Maotai liguor in inducing metallothioneins and on hepatic stellate cells显示文摘 | Cheng ML Wu J Wang HQ Xue LM Tan YZ Liu P Li CX Huang NH Yao YM Ren LZ Ye L Li L Jia ML | 2001 | Shijie Huaren Xiaohua Zazhi2001，9，12： | 2 |
| 8 | RHEOLOGICAL PROPERTIES OF METAL INVECTION MOLDING BINDER AND FEEDSTOCK显示文摘RHEOLOGICALPROPERTIESOFMETALINVECTIONMOLDINGBINDERANDFEEDSTOCK①LiYimin,QuXuanhui,HuangBaiyun,QiuGuanghanNationalKeyLaboratory... | Li, YM Qu, XH Huang, BY Qiu, GH | 1997 | 中国有色金属学会会刊:英文版1997，7，3： | 2 |
| 9 | Extracellular signal-regulated kinase pathways may mediate the protective effect of electrical stimulation of the paraventricular nucleus against ischaemia-reperfusion injury of the gastric mucosa 显示文摘 | Zhang YM Wei EQ Li L | 2007 | Clin Exp Pharmacol Physiol2007，34，8： | 1 |
| 10 | Regulation of hepatic microRNA expression in response to ischemic preconditioning following ischemia/reperfusion injury in mice显示文摘 | Xu CF Yu CH Li YM | 2009 | OMICS2009，13，6： | 1 |
| 11 | Effects of different magnitudes of mechanical strain on Osteoblasts in vitro显示文摘 | Tang L Lin Z Li YM | 2006 | Biochem Biophys Res Commun2006，344，1： | 1 |
| 12 | Chinese position and services of repeat and standardize abortion 显示文摘 | Cheng YM Li Y Guo X | 2004 | Chin J Pract Gyneco! Obstet2004，20，9： | 1 |
| 13 | Signaling mechanism of cell adhesion molecules in breast cancer metastasis: potential therapeutic targets显示文摘 | Li DM Feng YM | 2011 | Breast Cancer Res Treat2011，128，1： | 1 |
| 14 | Extensive enteric nervous system ab- normalities in mice transgenic for artificial chromosomes contai- ning Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes 显示文摘 | Kuo YM Li Z Jiao Y | 2010 | Hum Mol Genet2010，19，9： | 1 |
| 15 | Association analysis of single nucleo- tide polymorphisms of proinflammatory cytokine and their receptors genes with rheumatoid arthritis in northwest Chinese ttan population 显示文摘 | You CG Li XJ Li YM | 2013 | Cytokine2013，61，1： | 1 |
| 16 | Plasma levels of copeptin in patients with coronary heart disease显示文摘 | Chai SB Hui YM Li XM | 2009 | Heart Vessels2009，24，2： | 1 |
| 17 | HLA-G concentrations in maternal serum and placental tissue are decreased in preeclampsia显示文摘 | Yie SM Li LH Li YM | 2004 | Am J Obstet Gynecol2004，191，2： | 1 |
| 18 | Identification of a small molecule nonpeptide active site β- secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases 显示文摘 | Cobum CA Stachel SJ Li YM | 2004 | J Med Chem2004，47，25： | 1 |
| 19 | Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells显示文摘 | Li YM Broome JD | 1999 | Cancer Res1999，59，1： | 1 |
| 20 | Clinical analysis of salivary gland tumor cases in West China in past 50 years显示文摘 | Li IJ Li Y Wen YM | 2008 | Oral Oncol2008，44，2： | 1 |
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