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| 1 | Proteome analysis of alfalfa roots in response to water deficit stress显示文摘To evaluate the response of alfalfa to water deficit(WD) stress, WD-induced candidates were investigated through a proteomic approach. Alfalfa seedlings were exposed to WD stress for 12 and 15 days respectively, followed by 3 days re-watering. Water deficit increased H2O2 content, lipid peroxidation, DPPH(1,1-diphenyl-2-picrylhydrazyl)-radical scavenging activity, and the free proline level in alfalfa roots. Root proteins were extracted and separated by two-dimentional polyacrylamide gel electrophoresis(2-DE). A total of 49 WD-responsive proteins were identified in alfalfa roots; 25 proteins were reproducibly found to be up-regulated and 24 were down-regulated. Two proteins, namely cytosolic ascorbate peroxidase(APx2) and putative F-box protein were newly detected on 2-DE maps of WD-treated plants. We identified several proteins including agamous-like 65, albumin b-32, inward rectifying potassium channel, and auxin-independent growth promoter. The identified proteins are involved in a variety of cellular functions including calcium signaling, abacisic acid(ABA) biosynthesis, reactive oxygen species(ROS) regulation, transcription/ translation, antioxidant/detoxification/stress defense, energy metabolism, signal transduction, and storage. These results indicate the potential candidates were responsible for adaptive response in alfalfa roots. | Rahman Md Atikur Kim Yong-Goo Alam Iftekhar LIU Gong-she Lee Hyoshin Lee Jeung Joo Lee Byung-Hyun | 2016 | Journal of Integrative Agriculture2016，15，6： | 5 |
| 2 | 烧伤后深静脉血栓预防实用指南显示文摘深静脉血栓及其引起的肺栓塞是我国烧伤专科医护人员相对忽视的一种严重并发症,因其'极少发生'而疏于防范,在烧伤临床工作中,我们常常认为某些患者的猝死是由于'严重吸入性损伤'气道突然堵塞(尤其是使用翻身床翻身的患者)、脂肪乳输注不当、对重症烧伤患者护理不到位等引起,事实上,在这些猝死的患者中可能有一定比例的患者是由于致命性的肺血栓栓塞引起的,有些患者的深静脉血栓(DVT)由于同时合并下肢烧伤而'认为肢体肿胀系创面引起',从而遗漏了DVT的早期诊断、早期治疗,因此,可以认为目前我国烧伤临床所诊断的DVT/PTE可能只是冰山一角。事实上,近年来现代临床医学发现,DVT的发生率远较既往的'认为'要大,因此越来越重视DVT的预防和治疗,尤其是外科患者,在循证医学的基础上制定了外科患者DVT防治指南,烧伤专业虽系外科学的一个分支,但有其特殊性,目前国内外还没有一致的烧伤后DVT防治指南。我国烧伤专科医生对烧伤患者尤其是下肢烧伤、大面积烧伤患者普遍没有采取DVT/PTE的预防,但在美国,2005年有71个烧伤中心参与的一项调查发现,有75%的烧伤中心常规对烧伤患者进行DVT、预防,预防措施包括持续使用压迫器(装置)、皮下注射肝素和低分子肝素、静滴肝素,因此通过此文,希望能够提醒广大烧伤专科医护人员,要重视DVT/PTE的防治,同时也呼吁大家能够开展烧伤后DVT/PTE的流行病学调查和防治研究,因为到目前为止尚无有关DVT的循证医学的Ⅰ类证据指导临床。 | Lee D. Faucher MD KatheM.Conlon BSN RN CEM 高建川(编译) 丁一妹(编译) 孙永华(编译) | 2007 | 中华损伤与修复杂志(电子版)2007，2，4： | 5 |
| 3 | Borderline Resectable Pancreatic Cancer: Definitions, Management, and Role of Preoperative Therapy显示文摘 | Gauri R. Varadhachary MD Eric P. Tamm MD James L. Abbruzzese MD Henry Q. Xiong MD Christopher H. Crane MD Huamin Wang MD Jeffrey E. Lee MD Peter W. T. Pisters MD Douglas B. Evans MD Robert A. Wolff MD | 2006 | Annals of Surgical Oncology2006，，8： | 4 |
| 4 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 5 | Intraductal Papillary Mucinous Neoplasms of the Pancreas: Effect of Invasion and Pancreatic Margin Status on Recurrence and Survival显示文摘 | Chandrajit P. Raut MD Karen R. Cleary MD Gregg A. Staerkel MD James L. Abbruzzese MD Robert A. Wolff MD Jeffrey H. Lee MD Jean-Nicolas Vauthey MD Jeffrey E. Lee MD Peter W. T. Pisters MD Douglas B. Evans MD | 2006 | Annals of Surgical Oncology2006，，4： | 3 |
| 6 | Recurrence and Prognostic Factors of Ampullary Carcinoma after Radical Resection: Comparison with Distal Extrahepatic Cholangiocarcinoma显示文摘 | Sang Myung Woo MD Ji Kon Ryu MD Sang Hyub Lee MD Ji Won Yoo MD Joo Kyung Park MD Yong-Tae Kim MD Jin-Young Jang MD Sun-Whe Kim MD Gyeong Hoon Kang MD Yong Bum Yoon MD | 2007 | Annals of Surgical Oncology2007，，11： | 2 |
| 7 | Clinical Impact of Positive Surgical Margin Status on Gastric Cancer Patients Undergoing Gastrectomy显示文摘 | Shang-Yu Wang MD Chun-Nan Yeh MD Hsiang-Lin Lee MD Yu-Yin Liu MD Tzu-Chieh Chao MD PhD Tsann-Long Hwang MD FACS Yi-Yin Jan MD FACS Miin-Fu Chen MD FACS | 2009 | Annals of Surgical Oncology2009，，10： | 2 |
| 8 | Laparoscopic Pelvic Autonomic Nerve-Preserving Surgery for Patients with Lower Rectal Cancer after Chemoradiation Therapy显示文摘 | Jin-Tung Liang MD PhD Hong-Shiee Lai MD PhD Po-Huang Lee MD PhD | 2007 | Annals of Surgical Oncology2007，，4： | 2 |
| 9 | Liver Transplantation for Hepatocellular Carcinoma显示文摘 | Vincenzo Mazzaferro MD Yun Shin Chun MD Ronnie T. P. Poon MS PhD Myron E. Schwartz MD Francis Y. Yao MD J. Wallis Marsh MD Sherrie Bhoori MD Sung-Gyu Lee MD PhD | 2008 | Annals of Surgical Oncology2008，，4： | 2 |
| 10 | Selenocysteine tRNAs as Central Components of Selenoprotein Biosynthesis in Eukaryotes显示文摘Selenocysteine (Sec) tRNAs serve as carrier molecules for the biosynthesis of Sec from serine and to donate Sec to protein in response to specific UGA codons. In this study, we describe the current status of Sec tRNAs in higher animals and further we exarnine: (i) the Sec tRNA population in Drosophila; (ii) transcription of the Sec tRNA in vivo (in Xenopus oocytes) and in vitro (in Xenopus oocyte extracts); (iii) the effect of selenium on the Sec tRNA population in various rat tissues following replenishment of extremely selenium deficient rats with this element; and (iv) the biosynthesis of the modified bases on Sec tRNA in Xenopus | SANG ICK PARK JIN Mo PARK HAROLD S. CHITTUM EUN SUNG YANG BRADLEY A. CARLSON BYEONG JAE LEE AND DOLPH L. HATFIELD(Laboratory of Experimental Chrcinogenesis, National Cancer Insti tute, National Institutes of Health, Bethesda, MD 20892USA Laboratory o | 1997 | Biomedical and Environmental Sciences1997，10，2： | 2 |
| 11 | Prognostic Significance of Metastatic Lymph Node Ratio in Node-Positive Colon Carcinoma显示文摘 | Ho-Young Lee MD Hong-Jo Choi MD FACS Ki-Jae Park MD Jong-Sok Shin MD Hyuk-Chan Kwon MD Mee-Sook Roh MD Choongrak Kim PhD | 2007 | Annals of Surgical Oncology2007，，5： | 2 |
| 12 | Surgical Indication for Non-curative Endoscopic Resection in Early Gastric Cancer显示文摘 | Keun Won Ryu MD Il Ju Choi MD Young Woo Doh MD Myeong-Cherl Kook MD Chan Gyoo Kim MD Hyun-Jung Park RN Jun Ho Lee MD Jong-Seok Lee MD Jong Yeul Lee MD Young Woo Kim MD Jae-Moon Bae MD | 2007 | Annals of Surgical Oncology2007，，12： | 2 |
| 13 | Comparison of Central and Extended Left Pancreatectomy for Lesions of the Pancreatic Neck显示文摘 | Lee M. Ocuin MD Juan M. Sarmiento MD Charles A. Staley MD John R. Galloway MD Colin D. Johnson MD William C. Wood MD David A. Kooby MD | 2008 | Annals of Surgical Oncology2008，，8： | 2 |
| 14 | Extrapancreatic Malignancies in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas: Prevalence, Associated Factors, and Comparison with Patients with Other Pancreatic Cystic Neoplasms显示文摘 | Won Jae Yoon MD Ji Kon Ryu MD Jun Kyu Lee MD Sang Myung Woo MD Sang Hyub Lee MD Joo Kyung Park MD Yong-Tae Kim MD Yong Bum Yoon MD | 2008 | Annals of Surgical Oncology2008，，11： | 2 |
| 15 | Comparison of Surgical Resection and Transarterial Chemoembolization for Hepatocellular Carcinoma beyond the Milan Criteria: A Propensity Score Analysis显示文摘 | Chia-Yang Hsu MD Cheng-Yuan Hsia MD Yi-Hsiang Huang MD PhD Chien-Wei Su MD Han-Chieh Lin MD Jih-Tung Pai MD PhD Che-Chuan Loong MD PhD Yi-You Chiou MD Rheun-Chuan Lee MD Fa-Yauh Lee MD Teh-Ia Huo MD Shou-Dong Lee MD | 2012 | Annals of Surgical Oncology2012，，3： | 2 |
| 16 | Markedly Elevated Levels of Vascular Endothelial Growth Factor in Malignant Ascites显示文摘 | Brian K. Zebrowski MD Wenbiao Liu MD Karen Ramirez BS Yoshito Akagi MD Gordon B. Mills MD Lee M. Ellis MD | 1999 | Annals of Surgical Oncology1999，，4： | 2 |
| 17 | Recurrence Following Laparoscopy-Assisted Gastrectomy for Gastric Cancer: A Multicenter Retrospective Analysis of 1,417 Patients显示文摘 | Jyewon Song MD Hyuk-Joon Lee MD Gyu Seok Cho MD Sang-Uk Han MD Min-Chan Kim MD Seung Wan Ryu MD Wook Kim MD Kyo Young Song MD Hyung-Ho Kim MD Woo Jin Hyung MD | 2010 | Annals of Surgical Oncology2010，，7： | 2 |
| 18 | Risk Factors Associated with Complication Following Laparoscopy-Assisted Gastrectomy for Gastric Cancer: A Large-Scale Korean Multicenter Study显示文摘 | Min Chan Kim MD Wook Kim MD Hyung Ho Kim MD Seung Wan Ryu MD Seong Yeob Ryu MD Kyo Young Song MD Hyuk Joon Lee MD Gyu Seok Cho MD Sang Uk Han MD Woo Jin Hyung MD | 2008 | Annals of Surgical Oncology2008，，10： | 2 |
| 19 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 2 |
| 20 | A Gene Expression Profile for Vascular Invasion can Predict the Recurrence After Resection of Hepatocellular Carcinoma: a Microarray Approach显示文摘 | Ming-Chih Ho MD Jen-Jen Lin PhD Chiung-Nien Chen MD PhD Chaur-Chin Chen PhD Hsinyu Lee PhD Ching-Yao Yang MD Yen-Hsuan Ni MD PhD King-Jen Chang MD PhD Hey-Chi Hsu DDS Fon-Jou Hsieh MD Po-Huang Lee MD PhD | 2006 | Annals of Surgical Oncology2006，，11： | 1 |
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