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1自发性脑出血管理指南 美国心脏协会/美国卒中协会针对医疗专业人员的指南显示文摘目的本指南旨在为自发性脑出血的诊断和治疗提供最新的全面推荐意见。方法利用PubMed进行规范化文献检索,检索时间至2013年8月底。撰写委员会成员通过远程电信会议讨论指南内容及推荐意见,采用美国心脏协会/美国卒中协会的疗效确定性水平和证据分级方案对推荐意见进行分级。由6位同行评议专家以及卒中委员会科学声明监督委员会和卒中委员会领导委员会成员对指南草案进行发表前审阅。结果本文为急性脑出血患者的医疗诊治提供了循证指南,重点包括诊断、凝血功能障碍和血压管理、继发性脑损伤防治、颅内压控制、外科治疗的作用、转归预测、康复、二级预防以及将来需要考虑的问题。本指南已纳入最新的3期临床试验结果。结论脑出血是一种需要进行早期积极救治的危重疾病。本指南为脑出血患者的目标导向治疗提供了一个框架。J. Claude Hemphill Ⅲ Steven M. Greenberg Craig S. Anderson Kyra Beckelr Bernard R. Bendok Mary Cushman Gordon L. Fung Joshua N. Goldstein R. LochMacdonald Pamela H Mitchell, Phillip A Scott,Magdy H Selim, Daniel Woo 高圆圆 徐欣 2015国际脑血管病杂志2015,23,10:444
2Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt显示文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.Nizar Saleh Abdelfattah Mohamed Amgad Ahmed A Salama Marina E Israel Ghada A Elhawary Ahmed E Radwan Mohamed M Elgayar Tamer M EL Nakhal Islam T Elkhateb Heba A Hashem Doha K Embaby Amira A Elabd Reem K Elwy Magdi S Yacoub Hamdy Salem Mohamed Abdel-Baqy Ahmad Kassem 2014International Journal of Ophthalmology(English edition)2014,7,5:8
3Hepatitis C virus:A global view显示文摘Hepatitis C virus(HCV) is a global challenge; 130-175 million are chronically infected. Over 350000 die each year from HCV. Chronic HCV is the primary cause of cirrhosis, hepatocellular carcinoma(HCC), and end-stage liver disease. Management of chronic HCV is aimed at preventing cirrhosis, reducing the risk of HCC, and treating extra hepatic complications. New treatments for chronic HCV has been devoted based on direct-acting antivirals, as pegylated interferon(peginterferon) is responsible for many side effects and limits treatment access. Sofosbuvir is the first compound to enter the market with Peginterferon-free combination regimens.Amal Ahmed Mohamed Tamer A Elbedewy Magdy El-Serafy Naglaa El-Toukhy Wesam Ahmed Zaniab Ali El Din 2015World Journal of Hepatology2015,7,26:7
4Micro RNAs and clinical implications in hepatocellular carcinoma显示文摘AIM To assess the role of some circulating miRNAs(miR-23a, miR-203, miR338, miR-34, and miR-16) as tumor markers for diagnosis of hepatocellular carcinoma(HCC).METHODS One hundred and seventy-one subjects were enrolled, 57 patients with HCC, 57 patients with liver cirrhosis(LC) and 57 healthy subjects as control group. Severity of liver disease was assessed by Child Pugh score. Tumor staging was done using Okuda staging system. Quantification of Micro RNA(miR-23a, miR-203, miR338, miR-34, and miR-16) was performed.RESULTS All studied miRNA showed significant difference between HCC and cirrhotic patients in comparison tohealthy control. miR-23a showed statistically significant difference between HCC and cirrhotic patients being higher in HCC group than cirrhotic. miR-23a is significantly higher in HCC patients with focal lesion size equal or more than 5cm, patients with multiple focal lesions and Okuda stage Ⅲ. At cutoff value ≥ 210, miR-23a showed accuracy 79.3% to diagnose HCC patients with sensitivity 89.47% and specificity about 64.91%. At cut off level ≥ 200 ng/mL, serum alpha fetoprotein had 73.68% sensitivity, 52.63% specificity, 43.75% PPV, 80% NPV for diagnosis of HCC.CONCLUSION MicroR NA 23a can be used as a screening test for early detection of HCC. Also, it is related to larger size of tumour, late Okuda staging and multiple hepatic focal lesions, so it might be a prognostic biomarker.Amal Ahmed Mohamed Zainab A Ali-Eldin Tamer A Elbedewy Magdy El-Serafy Fatma A Ali-Eldin Hossameldin Abdel Aziz 2017World Journal of Hepatology2017,9,23:4
5Early detection of anastomotic leakage after elective low anterior resection 显示文摘Fouda E Nakeeb EA Magdy A 2011J Gastrointest Surg2011,15,1:1
6The phenomenolo- gy of premenstrual syndrome in female medical students : a cross sec- tional study显示文摘MAGDY H B MOSTAFA A E MONEM A 2014Pan African med J2014,65,10:1
7Friction stir processing:Aneffective technique to refine grain structure and enhanceductility显示文摘Ehab A El-Danaf Magdy M 2010Materials and Design2010,31,3:1
8The influence of multi-passfriction stir processing on the microstructural and mechanicalproperties of aluminum alloy 6082 显示文摘Magdy M El-Rayes Ehab A 2012Journal of MaterialsProcessing Technology2012,212,5:1
9Pfaffian solutions to a (3+1)-dimensional generalized B-type Kadomtsev-Petviashvili equation and its modified counterpart显示文摘Magdy G A Ma Wen-xiu 0,,9:1
10Synthesis,characterization and antimicrobial activity of poly ( N-vinyl imidazole ) grafted carboxymethyl chitosan显示文摘Magdy W Sabaa Nadia A Mohamed Riham R Mohamed 2010Carbohydrate Polymers2010,79,4:1
11Magnetothermoelasticity with two relaxation times in conducting medium with variable electrical and thermal conductivity显示文摘Magdy A Ezzat Ahmed S El-Karamany 2003Applied Mathematics and Computation2003,,142:1
12Chromatographic separation and identification of conjugated linoleic acid isomers显示文摘John A G Roach Magdi M Mossoba M Peter Yurawecz 2002Analytica Chimica Acta2002,465,:1
13Copper electrodeposition from nonpolluting aqueous ammonia baths显示文摘Magdy A M Ibrahim 2000Plating and Surface Finishing2000,87,7:1
14Genetic mapping of new cotton fiber loci using EST-derivedmicrosatellites in an interspecific recombinant inbred line cotton Population 显示文摘YOUNG H P Magdy S A Ulloa M 2005Mol Gen Genomics2005,274,:1
15Enhanced Spectral Reflectance Reconstruction Using Pseudo-Inverse Estimation Method 显示文摘ELRIFAI I A MAHGOUB H MAGDY M A 2013Computer Science Journals2013,7,3:1
16Unified approach for mitigating voltage sag and voltage flicker using the DSTATCOM显示文摘Einady A Magdy M M A 2005IEEE Transactions on Power Delivery2005,20,2:1
17Colorimetric determination of two fenamates in cap sule dosage form显示文摘MOHAMED S M MAGDI M A MOHAMED E A 1985Talanta1985,32,8:1
18Lipohypertrophy in children and adole-scents with type 1 diabetes and the associated factors显示文摘Magdy AO Ahmed A Ramy I 2011BMC Research Notes2011,8,4:1
19Early detection of anastomotic leakage after elective low anterior resection显示文摘Fouda E El Nakeeb A Magdy A 0,,01:1
20Can rhabdomylysis be a cause of sudden death in young athletes 显示文摘Stany Wilfred Lobo Sadip Pant Magdy A 2011Medical Hypotheses2011,77,5:1
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