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902篇 您的检索式:作者名="MALIK R"
    题名 作者 年代 出处 被引量
1Role of endoscopic therapy in early esophageal cancer显示文摘Esophageal carcinoma is a highly lethal cancer associated with high morbidity and mortality. Esophageal squamous cell carcinoma and esophageal adenocarcinoma are the two distinct histological types. There has been significant progress in endoscopic diagnosis and treatment of early stages of cancer using resection and ablation techniques, as shown in several trials in the recent past. Earlier detection of esophageal cancer and advances in treatment modalities have lead to improvement in the 5-year survival from 5% to about 20% in the past decade. Endoscopic eradication therapy is the preferred modality of treatment in cancer limited to mucosal layer of the esophagus as there is very low risk of lymph node metastasis, leading to high cure rates, low risk of recurrence and with few adverse effects. The most common adverse events seen are strictures, bleeding and rarely perforation which can be endoscopically managed. In patients with recurrent advanced disease or invasive tumor, esophagectomy with lymph node dissection remains the mainstay of treatment. There is debate on post-endoscopic surveillance with some studies suggesting closer follow up with upper endoscopy every 6 mo for the first 1-2 years and then annually for the 3 years while others recommending the appropriate action only if symptoms or other abnormalities develop. Overall, the field of endoscopic therapy is still evolving and focus should be placed on careful patient selection using a multidisciplinary approach.Sonika Malik Gautam Sharma Madhusudhan R Sanaka Prashanthi N Thota 2018World Journal of Gastroenterology2018,24,35:10
2Celecoxib-induced cholestatic liver failure requiring orthotopic liver transplantation显示文摘Selective cyclooxygenase-2 (COX-2) inhibitors are widely used due to their efficacy and good safety profile. However, recent case reports have described varying degrees of liver injuries associated with the use of COX-2 inhibitors. We report the case of a patient who developed acute cholestatic hepatitis progressing to hepatic failure requiring liver transplantation, following a 3-d course of celecoxib for treatment of generalized muscle aches and pains. The clinical presentation, the laboratory data, as well as the liver histopathology were supportive of the putative diagnosis of drug induced liver injury.Ihab I El Hajj Shahid M Malik Hany R Alwakeel Obaid S Shaikh Eizaburo Sasatomi Hossam M Kandil 2009World Journal of Gastroenterology2009,15,31:4
3利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I 2019中华高血压杂志2019,0,9:3
4输尿管及膀胱深部浸润型子宫内膜异位症的手术治疗效果显示文摘目的报告泌尿道子宫内膜异位症的手术治疗效果以及探讨保守型手术和根治性手术的选择。方法对5个手术科室参与的输尿管或膀胱深部浸润型子宫内膜异位症外科治疗的CIRENDO前瞻性数据库管理数据进行回顾性研究。对术前、术中和术后数据结果进行分析。结果数据库中的数据显示,30例中有15例为输尿管子宫内膜异位症,14例为膀胱结节病变(bladder nodules),1例同时存在这2种类型的病变。输尿管松解术14例,其中输尿管完全恢复解剖解构10例。4例40岁以上的患者术后出现闭经和可忍受的中度输尿管狭窄,其中3例好转,1例行二次输尿管切除和输尿管膀胱吻合术。4例初次手术行输尿管切除术。5例输尿管标本中发现2例输尿管子宫内膜异位症。4例并发症中有2例与输尿管结节病灶切除有关,2例与膀胱子宫内膜异位病灶切除有关。远期效果较为满意,如疼痛症状显著改善、泌尿系不适症状消失,仅有1例较长时间膀胱神经功能障碍。结论建议保守性手术联合术后假绝经疗法治疗大多数泌尿道子宫内膜异位症。尽管总体结果满意,由于术中可能同时施行其他一些复杂手术如结直肠手术,术后并发症的风险仍不容忽视。陈旭 刘彦 Francisc Rozsnyai Horace Roman Benoit Resch Fabrice Dugardin Juan Berrocal Gérme Descargues Remi Schmied Malik Boukerrou Loc Marpeau CIRENDO Study Group 2013中国微创外科杂志2013,13,2:3
5Transperineurial capillary abnormalities in the sural nerve of patients with diabetic neuropathy显示文摘MALIK R A TESFAGE S THOMPSON S D 1994Microvasc Res1994,48,2:2
6Utility of liver biopsy in predicting clinical outcomes after percutaneous angioplasty for hepatic venous obstruction in liver transplant patients显示文摘AIM: To determine utility of transplant liver biopsy in evaluating efficacy of percutaneous transluminal angioplasty(PTA) for hepatic venous obstruction(HVOO). METHODS: Adult liver transplant patients treated with PTA for HVOO(2003-2013) at a single institution were reviewed for pre/post-PTA imaging findings, manometry(gradient with right atrium), presence of HVOO on prePTA and post-PTA early and late biopsy(EB and LB, < or > 60 d after PTA), and clinical outcome, defined as good(no clinical issues, non-HVOO-related death) or poor(surgical correction, recurrent HVOO, or HVOOrelated death). RESULTS: Fifteen patients meeting inclusion criteria underwent 21 PTA, 658 ± 1293 d after transplant.In procedures with pre-PTA biopsy(n = 19), no difference was seen between pre-PTA gradient in 13/19 procedures with HVOO on biopsy and 6/19 procedures without HVOO(8 ± 2.4 mm Hg vs 6.8 ± 4.3 mm Hg; P = 0.35). Post-PTA, 10/21 livers had EB(29 ± 21 d) and 9/21 livers had LB(153 ± 81 d). On clinical follow-up(392 ± 773 d), HVOO on LB resulted in poor outcomes and absence of HVOO on LB resulted good outcomes. Patients with HVOO on EB(3/7 good, 4/7 poor) and no HVOO on EB(2/3 good, 1/3 poor) had mixed outcomes. CONCLUSION: Negative liver biopsy greater than 60 d after PTA accurately identifies patients with good clinical outcomes.Ammar Sarwar Edward Ahn Ian Brennan Olga R Brook Salomao Faintuch Raza Malik Khalid Khwaja Muneeb Ahmed 2015World Journal of Hepatology2015,7,14:2
7RNA regulation and cancer development显示文摘Scholzova E Malik R Sevcik J 2007Cancer Lett2007,246,12:1
8Influence of mixed probiotic on growth,feed conversion efficiency and incidence of diarrhoea in young calves显示文摘Raman M Sharma D D Malik R 1998Indian Journal of Animal Nutrition1998,15,3:1
9Packing material and ripening methods affect mango fruit quality显示文摘ANWAR R MALIK A U AMIN M 2008Int J Agri Biol2008,,10:1
10Learning to detect natu- ral image boundaries using local brightness, color, and tex- ture cues 显示文摘Martin D R Fowlkes C C Malik J 2004IEEE Trans on Pattern Anlaysis and Machine Intelligence2004,26,5:1
11Dynamic capabilities, govern ment policies and performance in firms from emerging e conomies: evidence from India and Pakistan显示文摘MALIK O R KOTABE M 2009Journal of Management Studies2009,,5:1
12Effect of inorganic nitrogen supplementation on biogas production显示文摘Malik R K SinSh R Tauro P 1987Biological Wastes Wastes1987,21,2:1
13Endovascular treatment of tandem extracranial/intracranial anterior circulation occlusions:preliminary single-center experience显示文摘Malik AM Vora NA Lin R 2011Stroke2011,42,:1
14Lymphangiogenesis concurrent with haemangiogenesis in the human cornea显示文摘Regina M Zimmerman R Malik G 0,,6:1
15Randomized controlled trial of the Pentax AWS,Glidescope,and Macintosh laryngoscopes in predicted difficult intubation显示文摘Malik MA Subramaniam R Maharaj CH 2009Br J Anaesth2009,103,5:1
16Magnetic structure of the SmsGe4-type Tb2Ti3Ge4显示文摘Morozkin A V Nirmala R Malik S K 2012Journal of Magnetism and Magnetic Mate- rials2012,324,:1
17Temperature-enthalpy curve for energy targeting of distillation columns显示文摘Bandyopadhyay S Malik R Shenoy U 1998Computer Chemical Engineering1998,22,3:1
18Phytoremediation of soil metals显示文摘Chaney R L Malik K M Li Y M 1997Cur Opin Biotechnol1997,8,2:1
19The relationship between the thyroid gland and the liver显示文摘Malik R Hodgson H 2002Q J Med2002,95,:1
20Phytoremediation of soil metals显示文摘Chaney R L Malik M Li Y M 1997Current Opinions in Biotechnology1997,8,:1
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