|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bilirubin in coronary artery disease:Cytotoxic or protective?显示文摘Bilirubin has traditionally been considered a cytotoxic waste product.However,recent studies have shown bilirubin to have anti-oxidant,anti-inflammatory,vasodilatory,anti-apoptotic and anti-proliferative functions.These properties potentially confer bilirubin a new role of protection especially in coronary artery disease(CAD),which is a low grade inflammatory process exacerbated by oxidative stress.In fact,recent literature reports an inverse relationship between serum concentration of bilirubin and the presence of CAD.In this article,we review the current literature exploring the association between levels of bilirubin and risk of CAD.We conclude that current evidence is inconclusive regarding the protective effect of bilirubin on CAD.A causal relationship between low serum bilirubin level and increased risk of CAD is not currently established. | Nancy Gupta Tavankit Singh Rahul Chaudhary Sushil K Garg Gurprataap Singh Sandhu Varun Mittal Rahul Gupta Roxana Bodin Sachin Sule | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，4： | 14 |
| 2 | Gastric remnant twist in the immediate post-operative period following laparoscopic sleeve gastrectomy显示文摘Twist of stomach remnant post sleeve gastrectomy is a rare entity and difficult to diagnose pre-operatively. We are reporting a case of gastric volvulus post laparoscopic sleeve gastrectomy, which was managed conservatively. A 38-year-old lady with a body mass index of 54 underwent laparoscopic sleeve gastrectomy. Sleeve gastrectomy was performed over a 32 French bougie using Endo-GIA tri-stapler. On post-operative day 1, patient had nausea and non-bilious vomiting. An upper gastrointestinal gastrografin study on postoperative days 1 and 2 revealed collection of contrast in the fundic area of stomach with poor flow distally, and she vomited gastrograffin immediately post procedure. With the suspicion of a stricture in the mid stomach as the cause, the patient was taken back for a exploratory laparoscopy and intra-operative endoscopy. We found a twist in the gastric tube which was too tight for the endoscope to pass through. This was managed conservatively with a long stent to keep the gastric tube straight and patent. The stent was discontinued in 7 d and the patient did well. In laparoscopic sleeve gastrectomy the stomach is converted into a tube and is devoid of its supports. If the staples fired are not aligned appropriately, it can predispose this stomach tube to undergo torsion along its long axis. Such a twist can be avoided by properly aligning the staples and by placing tacking sutures to the omentum and new stomach tube. This twist is a functional obstruction rather than a stricture; thus, it can be managed by endoscopy and stent placement. | Gokulakkrishna Subhas Anupam Gupta Mubashir Sabir Vijay K Mittal | 2015 | World Journal of Gastrointestinal Surgery2015，7，11： | 6 |
| 3 | Animal models of human colorectal cancer:Current status, uses and limitations显示文摘AIM: To make orthotopic colon cancer murine modelsa more clearly understood subject. The orthotopic tumor models have been found to be more relevant in replicating the human disease process as compared to heterotopic models, many techniques for making orthotopic colorectal murine models have been reported.METHODS: We evaluated the current literature for various reported orthotopic colon cancer models to understand their techniques, advantages and limitations. An extensive literature review was performed by searching the National Library of Medicine Database(Pub Med) using Me SH terms animal model; colon cancer; orthotopic model; murine model. Twenty studies related to colon cancer orthotopic xenograft model were evaluated in detail and discussed here. RESULTS: The detailed analysis of all relevant reports on orthotopic model showed tumor take rate between 42%-100%. While models using the enema technique and minimally invasive technique have reported development of tumor from mucosa with tumor take rate between 87%-100% with metastasis in 76%-90%.CONCLUSION: Over the years, the increased understanding of the murine models of human colon cancer has resulted in the development of various models. Each reported model has some limitations. These latest models have opened up new doors for continuing cancer research for not only understanding the colon cancer pathogenesis but also aid in the development of newer chemotherapeutic drugs as they mimic the human disease closely. | Vijay K Mittal Jasneet Singh Bhullar Kumar Jayant | 2015 | World Journal of Gastroenterology2015，21，41： | 5 |
| 4 | Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation 显示文摘 | Mittal A Elmets C A Katiyar S K | 2003 | Carcinogenesis2003，24，8： | 2 |
| 5 | Factors involved in immunity against Actinobacillus pleuropneumoniae 显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbiol1991，29，： | 2 |
| 6 | DDT residues in the River Jamuna in Delhi, India 显示文摘 | Agarwal H C Mittal P K Menon K B | 1986 | Wat Air Soil Pollut1986，28，： | 2 |
| 7 | Management of enterocutaneous fistulae:A 10 years experience显示文摘AIM:To compare the outcomes of conservative vs surgical treatment of enterocutaneous fistulae(ECF) in a community teaching hospital over a decade.METHODS:All cases of ECF between 1997 and 2007 were reviewed for management strategy.RESULTS:Of the 83 patients with ECF,60(72%) were postoperative.Sixty-six patients(79.5%) were treated initially with conservative measures.Eighteen patients failed to respond to conservative treatment and required later(secondary) exploration;this group consisted of an equal number of low vs high output fistulae.Seventeen(20.5%) patients underwent initial(primary) def initivesurgery secondary to anastomotic leak and peritonitis.Surgical procedures included resection of ECF with anastomosis(24),exclusion(6) and direct-drainage(4).No signif icant difference was seen in the recurrence rate for conservative(10%) vs operative-treatment(20%).role as an initial management in both low and high output fistulae.In selective cases only,early primary exploration is recommended. | Deepa Taggarshe Daniel Bakston Michael Jacobs Alasdair McKendrick Vijay K Mittal | 2010 | World Journal of Gastrointestinal Surgery2010，2，7： | 2 |
| 8 | Molecular basis of aggressive disease in chronic lymphocytic leukemia patients with 11q deletion and trisomy 12 chromosomal abnormalities显示文摘 | MITTAL A K HEGDE G V AOUN P | 2007 | Int J Mol Med2007，20，4： | 1 |
| 9 | Factors involved in immunity a- gainst Actinobacillus pleuropneumoniae in mice显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbi- ol1991，29，2： | 1 |
| 10 | Tissue distribution and genetic typing of Porcine circoviruses in pigs with naturally occurring congenital tremors显示文摘 | Stevenson G W Kiupel M Mittal S K | 2001 | J Vet Diagn Invest2001，13，1： | 1 |
| 11 | No-reference image quality assessment in the spatial domain 显示文摘 | Mittal A Moorthy A K Bovik A C | 2012 | IEEE Transactions on Image Processing2012，21，12： | 1 |
| 12 | Tissue distribution and genetic typing of porcine circoviruses in pigs with naturally occurring congenital tremors 显示文摘 | Stevenson G W Kiupel M Mittal S K | 2001 | Journal of Veterinary Diagnostic Investiga- tion2001，13，1： | 1 |
| 13 | No-reference image quality assessment in the spatial domain 显示文摘 | MITTAL A MOORTHY A K BOVIK A C | 2012 | IEEE Transactions on Image Processing2012，21，12： | 1 |
| 14 | Optimal manipulator parameter tolerance selection using evolutionary optimization technique 显示文摘 | Rout B K Mittal R K | 2008 | Engi- neering Applications of Artificial Intelligence2008，21，4： | 1 |
| 15 | Effect of architecture on mechanical properties of carbon/carbon composites 显示文摘 | Rao M V Mahajan P Mittal P K | 2008 | Composite Structure2008，83，2： | 1 |
| 16 | Factors involved in immunity against Actionbacillus pleuropmeumonia in mice 显示文摘 | Bhatia B Mittal K R Frey J | 1991 | Vet Microbiol1991，29，： | 1 |
| 17 | No-reference image quality assessment in the spatial domain显示文摘 | MITTAL A MOORTHY A K BOVIK A C | 2012 | IEEE Transactions on Image Processing2012，21，12： | 1 |
| 18 | Hypervascular hepatic focal lesions: spectrum of imaging features 显示文摘 | Namasivayam S Salman K Mittal PK | 2007 | Curr Probl Diagn Radiol2007，36，3： | 1 |
| 19 | Parametric design optimization of 2-DOF R-R planar manipulator:a design of experiment approach显示文摘 | ROUT B K MITTAL R K | 2006 | Robotics and Computer-Integrated Manufacturing2006，24，2： | 1 |
| 20 | Role of outer membrane pro- tein H(OmpH)-and OmpA-Specific monoclonal antibodies from hybridoma tumors in protection of mice against Pas- teurella multocida 显示文摘 | Vasfimarandi M Mittal K R | 1997 | Infection and Immunity1997，65，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员