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| 1 | Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems显示文摘 | Annika Reintam Blaser Manu L. N. G. Malbrain Joel Starkopf Sonja Fruhwald Stephan M. Jakob Jan Waele Jan-Peter Braun Martijn Poeze Claudia Spies | 2012 | Intensive Care Medicine2012，，3： | 4 |
| 2 | Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study显示文摘 | Annika Reintam Blaser Martijn Poeze Manu L. N. G. Malbrain Martin Bj?rck Heleen M. Oudemans-van Straaten Joel Starkopf | 2013 | Intensive Care Medicine2013，，5： | 3 |
| 3 | Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome显示文摘 | Andrew W. Kirkpatrick Derek J. Roberts Jan Waele Roman Jaeschke Manu L. N. G. Malbrain Bart Keulenaer Juan Duchesne Martin Bjorck Ari Leppaniemi Janeth C. Ejike Michael Sugrue Michael Cheatham Rao Ivatury Chad G. Ball Annika Reintam Blaser Adrian Regli Zs | 2013 | Intensive Care Medicine2013，，7： | 2 |
| 4 | Effect of intra-abdominal pressure on respiratory function in patients undergoing ventral hernia repair显示文摘AIM: To determine the influence of intra-abdominal pressure(IAP) on respiratory function after surgical repair of ventral hernia and to compare two different methods of IAP measurement during the perioperative period. METHODS: Thirty adult patients after elective repair of ventral hernia were enrolled into this prospective study.IAP monitoring was performed via both a balloontipped nasogastric probe [intragastric pressure(IGP), Ci MON, Pulsion Medical Systems, Munich, Germany] and a urinary catheter [intrabladder pressure(IBP), Uno Meter Abdo-Pressure Kit, Uno Medical, Denmark] on five consecutive stages:(1) after tracheal intubation(AI);(2) after ventral hernia repair;(3) at the end of surgery;(4) during spontaneous breathing trial through the endotracheal tube; and(5) at 1 h after tracheal extubation. The patients were in the complete supine position during all study stages.RESULTS: The IAP(measured via both techniques) increased on average by 12% during surgery compared to AI(P < 0.02) and by 43% during spontaneous breathing through the endotracheal tube(P < 0.01). In parallel, the gradient between РаСО2 and Et CO2 [Р(а-et)CO2] rose significantly, reaching a maximum during the spontaneous breathing trial. The PаO2/Fi O2 decreased by 30% one hour after tracheal extubation(P = 0.02). The dynamic compliance of respiratory system reduced intraoperatively by 15%-20%(P < 0.025). At all stages, we observed a significant correlation between IGP and IBP(r = 0.65-0.81, P < 0.01) with a mean bias varying from-0.19 mm Hg(2SD 7.25 mm Hg) to-1.06 mm Hg(2SD 8.04 mm Hg) depending on the study stage. Taking all paired measurements together(n = 133), the median IGP was 8.0(5.5-11.0) mm Hg and the median IBP was 8.8(5.8-13.1) mm Hg. The overall r2 value( n = 30) was 0.76(P < 0.0001). Bland and Altman analysis showed an overall bias for the mean values per patient of 0.6 mm Hg(2SD 4.2 mm Hg) with percentage error of 45.6%. Looking at changes in IAP between the different study stages, we found an excellent concordance coefficient of 94.9% comparing IBP and IGP( n = 117).CONCLUSION: During ventral hernia repair, the IAP rise is accompanied by changes in Р(а-et)CO2 and PаO2/Fi O2-ratio. Estimation of IAP via IGP or IBP demonstrated excellent concordance. | Konstantin M Gaidukov Elena N Raibuzhis Ayyaz Hussain Alexey Y Teterin Alexey A Smetkin Vsevolod V Kuzkov Manu LNG Malbrain Mikhail Y Kirov | 2013 | World Journal of Critical Care Medicine2013，2，2： | 2 |
| 5 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 2 |
| 6 | Assessing fluid responsiveness with the passive leg raising maneuver in patients with increased intra-abdominal pressure: Be aware that not all blood returns!显示文摘 | Manu L. N. G. Malbrain Daniel A. Reuter | 2010 | Critical Care Medicine2010，，9： | 1 |
| 7 | Thrombocytopenia and prognosis in intensive care显示文摘 | Steven Vanderschueren Annick De Weerdt Manu Malbrain Dominique Vankersschaever Eric Frans Alexander Wilmer Herman Bobbaers | 2000 | Critical Care Medicine2000，，6： | 1 |
| 8 | Results from the international conference of experts on intra - abdominal hypertension and abdominal compartment syndrome 显示文摘 | Manu LNG Malbrain Michael LC | 2006 | Intensive Care Med2006，32，： | 1 |
| 9 | Fluid management in critically ill patients: the role of extravascular lung water, abdominal hypertension, capillary leak, and fluid balance显示文摘 | Colin Cordemans Inneke De laet Niels Van Regenmortel Karen Schoonheydt Hilde Dits Wolfgang Huber Manu Malbrain | 2012 | Annals of Intensive Care2012，，1： | 1 |
| 10 | Abdominal compartment syndrome: it’s time to pay attention.显示文摘 | Manu L. N. G. Malbrain Michael L. Cheatham Andrew Kirkpatrick Michael Sugrue Jan Waele Rao Ivatury | 2006 | Intensive Care Medicine2006，，11： | 1 |
| 11 | Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations显示文摘 | Michael L. Cheatham Manu L. N. G. Malbrain Andrew Kirkpatrick Michael Sugrue Michael Parr Jan Waele Zsolt Balogh Ari Lepp?niemi Claudia Olvera Rao Ivatury Scott D’Amours Julia Wendon Ken Hillman Alexander Wilmer | 2007 | Intensive Care Medicine2007，，6： | 1 |
| 12 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 1 |
| 13 | Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions显示文摘 | Manu L. N. G. Malbrain Michael L. Cheatham Andrew Kirkpatrick Michael Sugrue Michael Parr Jan Waele Zsolt Balogh Ari Lepp?niemi Claudia Olvera Rao Ivatury Scott D’Amours Julia Wendon Ken Hillman Kenth Johansson Karel Kolkman Alexander Wilmer | 2006 | Intensive Care Medicine2006，，11： | 1 |
| 14 | Current insights in intra-abdominal hypertension and abdominal compartment syndrome: open the abdomen and keep it open.显示文摘 | Inneke E. laet Mariska Ravyts Wesley Vidts Jody Valk Jan J. Waele Manu L. N. G. Malbrain | 2008 | Langenbeck’s Archives of Surgery2008，，6： | 1 |
| 15 | Results from the international conference of experts on intra-abdominal hypertension and abdominal compartment syndrome 显示文摘 | Manu L Malbrain N G Michael L | 2006 | Intensive Care Med2006，32，11： | 1 |
| 16 | Prevalence of intra-abdominal hypertension in critically ill patients:a multicentre epidemiological study显示文摘 | Manu LNG Malbrain ML Davide Chiumello | | 0，，30： | 1 |
| 17 | Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. II. Recommendations显示文摘 | Michael L. Cheatham Manu L. N. G. Malbrain Andrew Kirkpatrick Michael Sugrue Michael Parr Jan Waele Zsolt Balogh Ari Lepp?niemi Claudia Olvera Rao Ivatury Scott D’Amours Julia Wendon Ken Hillman Alexander Wilmer | 2007 | Intensive Care Medicine2007，，6： | 1 |
| 18 | Results from the international conference of experts on intra - abdominal hypertension and abdominal compartment syndrome显示文摘 | Manu LNG Malbrain MLC | 2006 | Definitions Intensive Care Med2006，32，： | 1 |
| 19 | Thrombocytopenia and prognosis in intensive care显示文摘 | STEVEN VANDERSCHUEREN M D PHD ANNICK DE WEERDTM D MANU MALBRAIN M D | 2000 | Crit Care Med2000，28，6： | 1 |
| 20 | Goal-directed fluid resuscitation in acute pancreatitis: shedding light on the penumbra by dynamic markers of preload?显示文摘 | Wolfgang Huber Manu L. N. G. Malbrain | 2013 | Intensive Care Medicine2013，，4： | 1 |
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