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| 1 | Efficacy and safety of liquid nitrogen cryotherapy for treatment of Barrett's esophagus显示文摘AIM To evaluate the efficacy and safety of liquid nitrogen cryotherapy as a primary or rescue treatment for BE,with and without dysplasia,or intramucosal adenocarcinoma (IMC).METHODS This was a retrospective,single-center study carried out in a tertiary care center including 45 patients with BE who was treatment-na?ve or who had persistent intestinal metaplasia(IM),dysplasia,or IMC despite prior therapy.Barrett's mucosa was resected via EMR when clinically appropriate,then patients underwent cryotherapy until eradication or until deemed to have failed treatment.Surveillance biopsies were taken at standard intervals.RESULTS From 2010 through 2014,33 patients were studied regarding the efficacy of cryotherapy.Overall,29 patients (88%) responded to cryotherapy,with 84% having complete regression of all dysplasia and cancer.Complete eradication of cancer and dysplasia was seen in 75% of subjects with IMC; the remaining two subjects did not respond to cryotherapy.Following cryotherapy,15 patients with high-grade dysplasia (HGD) had 30% complete regression,50% IM,and 7% low-grade dysplasia (LGD); one subject had persistent HGD.Complete eradication of dysplasia occurred in all 5 patients with LGD.In 5 patients with IM,complete regression occurred in 4,and IM persisted in one.In 136 cryotherapy sessions amongst 45 patients,adverse events included chest pain (1%),stricture (4%),and one gastrointestinal bleed in a patient on dual antiplatelet therapy who had previously undergone EMR.CONCLUSION Cryotherapy is an efficacious and safe treatment modality for Barrett's esophagus with and without dysplasia or intramucosal adenocarcinoma. | Kristen Suchniak-Mussari Charles E Dye Matthew T Moyer Abraham Mathew Thomas J McGarrity Eileen M Gagliardi Jennifer L Maranki John M Levenick | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，9： | 4 |
| 2 | Multiple type-B re-sponse regulators mediate cytokinin signal transduction in Arabidopsis显示文摘 | MASON M G MATHEWS D E ARGYROS D A | 2005 | Plant Cell2005，17，： | 1 |
| 3 | Bridged y-carbolines and derivatives possessing selective and combined affinity for 5-HT2 and D2 receptors 显示文摘 | MEWSHAW R E SILVERMAN L S MATHEW R M et aJ | 1993 | J Med Chern1993，36，10： | 1 |
| 4 | Domains of elF1A that mediate binding to elF2, elF3 and elF5B and promote ternary complex recruitment in vivo 显示文摘 | Olsen D A S Savner E M Mathew A | 2003 | The EM- BO journal2003，22，2： | 1 |
| 5 | Control of hyperhydricity of mango somatic embryos显示文摘 | MONSALUD M J MATHEWS H LITZ R E | 1995 | Plant Cell Tissue and Organ Culture1995，42，2： | 1 |
| 6 | Transforming growth factor-beta in benign and maligant prostate 显示文摘 | Lee C Sintich S M Mathews E P | 1999 | Prostate1999，34，4： | 1 |
| 7 | Factors influencing the careseeking behaviour of chest symptomatics: a community-based study involving rural and urban population in Tamil Nadu, South India 显示文摘 | Sudha G Nirupa C Rajasakthivel M Sivasusbramanian S Sundaram V Bhatt S Subramaniam K Thiruvalluvan E Mathew R Renu G Santhal T | 2003 | Tropical Medicine and International Health2003，8，4： | 1 |
| 8 | Effects of a direct-fed yeast culture on enteric microbial populations,fermentation acids,and performance of weanling pigs显示文摘 | MATHEW A G CHATTIN S E ROBBINS C M | 1998 | Journal of Animal Science1998，76，： | 1 |
| 9 | 6-Shogaol inhibits monosodium urate crystal-induced inflammation- an in vivo and in vitro study 显示文摘 | Sabina E P Rasool M Mathew L | 2010 | Food Chem Toxicol2010，48，1： | 1 |
| 10 | Genetic diversity of rotavirus genome segment 6(encoding VP6)in Pretoria,South Africa显示文摘 | MARTIN M N MATHEW D E KHUZWAYO C J | 2014 | SpringerPlus2014，3，179： | 1 |
| 11 | Acute massive fetomaternal hemorrhage : case reports and review of the literature显示文摘 | Thomas A Mathew M Uunciano-Moral E | 2003 | Acta obstet Gynecol Scand2003，82，5： | 1 |
| 12 | Interactions of monensin with dietary fat and carbohydrate components on ruminal fermentation and production responses by dairy cows显示文摘 | Mathew B Eastridge M L Oelke E R | 2011 | J Dairy Sci2011，94，： | 1 |
| 13 | Factors influencing the careseeking behaviour of chest symptomatics: a community-based study involving rural and urban population in Tamil Nadu, South India 显示文摘 | Sudha G Nirupa C Rajasakthivel M Sivasusbramanian S Sundaram V Bhatt S Subrananiam K Thiruvalluvan E Mathew R Renu G Santhal T | 2003 | Trop Med Int Health2003，8，4： | 1 |
| 14 | Uterine pro- gesterone receptor expression,conceptus development,and ovarian function in pigs treated with RU 486 during early pregnancy显示文摘 | Mathew D J Sellner E M Green J C | 2011 | Reprod2011，84，1： | 1 |
| 15 | Interactions of monensin with dietary fat and carbohydrate components on ruminal fermentation and production responses by dairy cows显示文摘 | Mathew B Eastridge M L Oelker E R | 2011 | J Dairy Sci2011，94，： | 1 |
| 16 | Squamous cell carcinoma of the tongue among young Indian adults显示文摘 | Mathew Iype E Pandey M Mathew A | 2001 | Neo- plasia2001，3，4： | 1 |
| 17 | Influence of galaetosyi lactose on energy and protein digestibility, enteric microflora and performance of weanling pigs 显示文摘 | Mathew A G Robbins C M Chattin S E | 1997 | J Anita Sei1997，75，： | 1 |
| 18 | Influence of subsur- face drainage on crop production and soil quality in a low-lying acid sulphate soil 显示文摘 | Mathew E K Panda R K Nair M | 2001 | Agricultural Water Management2001，47，3： | 1 |
| 19 | Primary sarcoma of the breast显示文摘 | Pandey M Mathew A Abraham E K | 2004 | J Surg Oncol2004，87，3： | 1 |
| 20 | Acute massive feto- maternal hemorrhage : case reports and review of the literature 显示文摘 | Thomas A Mathew M Unciano Moral E | 2003 | Acta Obstet Gynecol Scand2003，82，5： | 1 |
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