|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Current and future treatments for hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) represents a unique challenge for physicians and patients.There is no definitively curative treatment.Rather,many treatment and management modalities exist with differing advantages and disadvantages.Both current guidelines and individual patient concerns must be taken into account in order to properly manage HCC.In addition,quality of life issues are particularly complex in patients with HCC and these concerns must also be factored into treatment strategies.Thus,considering all the options and their various pros and cons can quickly become complex for both clinicians and patients.In this review,we systematically discuss the current treatment modalities available for HCC,detailing relevant clinical data,risks and rewards and overall outcomes for each approach.Surgical options discussed include resection,transplantation and ablation.We also discuss the radiation modalities:conformal radiotherapy,yttrium 90 microspheres and proton and heavy ion radiotherapy.The biologic agent Sorafenib is discussed as a promising new approach,and recent clinical trials are reviewed.We then detail currently described molecular pathways implicated in the initiation and progression of HCC,and we explore the potential of each pathway as an avenue for drug exploitation.We hope this comprehensive and forward-looking review enables both clinicians and patients to understand various options and thereby make more informed decisions regarding this disease. | Alexander Schlachterman Willie W Craft Jr Eric Hilgenfeldt Avir Mitra Roniel Cabrera | 2015 | World Journal of Gastroenterology2015，21，28： | 76 |
| 2 | 慢性肾脏病中的炎症和动脉硬化:慢性肾功能不全队列研究中的发现显示文摘慢性肾脏病(chronic kidney disease,CKD)和动脉硬化程度与心血管病发病率和死亡率增加相关。目前认为炎症在动脉硬化发展中发挥作用,而CKD被认为是一种促炎症反应的状态。CKD患者的动脉僵硬度增加,横断面数据提示CKD中增多的炎症标志物与较高动脉僵硬度值相关。 | Peyster E Chen J Feldman HI Go AS Gupta J Mitra N Pan Q Porter A Rahman M Raj D Reilly M Wing MR Yang W Townsend RR 陈云 叶鹏 | 2017 | 中华高血压杂志2017，25，11： | 12 |
| 3 | Institutional stock ownership, accrual management, and information environment 显示文摘 | Mitra S Cready W M | 2005 | Journal of Accounting Auditing & Finance2005，20，3： | 1 |
| 4 | Longitudinal study of vertebral type-1 end-plate changes on MR of the lumbar spine显示文摘 | Mitra D Cassar Pullicino V N McCall I W | 2004 | Eur Radiol2004，14，： | 1 |
| 5 | Rough-fuzzy collab- orative clustering显示文摘 | Mitra S Banka H Pedrycz W | 2006 | IEEE Transactions on Sys- tems Man and Cybernetics: Part B2006，36，4： | 1 |
| 6 | Erythropoietin ameliorates renal dysfunction during endotoxaemia 显示文摘 | Mitra A Bansal S Wang W | 2007 | Nephrol Dial Transplant2007，22，8： | 1 |
| 7 | Collaborative Rough Clustering 显示文摘 | Mitra S Banka H Pedrycz W | 2005 | Lecture Notes in Computer Science2005，3776，： | 1 |
| 8 | Shadowed c-means: Integrating fuzzy and rough clustering显示文摘 | Mitra S Pedrycz W Barman B | 2010 | Pattern Recognition2010，43，4： | 1 |
| 9 | Shadowed c-means: integrating fuzzy and rough clustering 显示文摘 | Mitra S Pedrycz W Barman B | 2010 | Pattern Recognition2010，43，4： | 1 |
| 10 | On the equivalence of three reduced rank linear estimators with applications to DS-CDMA 显示文摘 | CHEN W MITRA U SCHNITER P | 2002 | IEEE Transactions on Information Theory2002，48，9： | 1 |
| 11 | Synthetic neoglycopolymer-recombinant human collagen hybrids as biomimetic crosslinking agents in corneal tissue engineering显示文摘 | Merrett K Liu W Mitra D | 2009 | Biomaterials2009，30，： | 1 |
| 12 | Three-dimensional structural model of the Rhourde el Baguel field, Algeria 显示文摘 | Mitra S Leslie W | 2003 | AAPG Bulle- tin2003，87，2： | 1 |
| 13 | Relaxation mechanisms at the interfaces in XDTM Al/TiCp metal matrix composites显示文摘 | MITRA R CHINA W A WEERTYOAN J R | 1991 | Scripta Metall Mater1991，25，6： | 1 |
| 14 | Immunolocalization of estrogen receptor beta in the mouse brain:comparison with estrogen receptor alpha显示文摘 | Mitra S W Hoskin E Yudkovitz J | 2003 | Endocrinology2003，144，5： | 1 |
| 15 | Three-dimensional structural model ofthe Rhourdeel Baguel field,Algeria显示文摘 | Mitra S Leslie W | 2003 | AAPG Bulle-tin2003，87，2： | 1 |
| 16 | Critical role for integrin- :4 in the attenuation of murine acute lung injury by simvastatin显示文摘 | Chen W Sammani S Mitra S | 2012 | Am J Physiol Lung Cell Mol Physiol2012，303，4： | 1 |
| 17 | Rough-fuzzy collaborative clustering 显示文摘 | Mitra S Banka H Pedrycz W | 2006 | IEEE Transactions on Systems Man and Cyber- netics2006，36，4： | 1 |
| 18 | Erythropoietin ameliorates renal dysfunction during endotoxaemia显示文摘 | Mitra A Bansal S Wang W | 2007 | Nephrol Dial Transplant2007，22，8： | 1 |
| 19 | Rapid chromatographic technique for preparative separations with moderate resolution 显示文摘 | Still C W Kahn M Mitra A | 1978 | J OrgChem1978，43，14： | 1 |
| 20 | Shadowed C-means: Integrating fuzzy and rough clustering 显示文摘 | Mitra S Pedrycz W Barman B | 2008 | Pattern Recognition2008，43，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员