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460篇 您的检索式:作者名="Miyano"
    题名 作者 年代 出处 被引量
1Mutations in hepatitis B virus core regions correlate with hepatocellular injury in Chinese patients with chronic hepatitis B显示文摘AIM: To elucidate the relationship between the frequency of core mutations and the clinical activity of hepatitis B virus (HBV)-related liver disease and to characterize the amino acid changes in the core region of HBV.METHODS: We studied 17 Chinese patients with chronic hepatitis B according to their clinical courses and patterns of the entire core region of HBV.RESULTS: Amino acid changes often appeared in the HBV core region of the HBV gene in patients with high values of alanine aminotransferase (ALT) or with the seroconversion from HbeAg to anti-HBe. The HBV core region with amino acid changes had high frequency sites that corresponded to HLA Ⅰ/Ⅱ restricted recognition epitopes reported by some investigators.CONCLUSION: The core amino acid changes of this study occur due to influence of host immune system. The presence of mutations in the HBV core region seems to be important for predicting the clinical activity of hepatitis B in Chinese patients.Hiroto Tanaka Hiroki Ueda Hiroko Hamagami Susumu Yukawa Masakazu Ichinose Motoshige Miyano Keiji Mimura Iwao Nishide Bo-Xin Zhang Su-Wen Wang Shi-Oing Zhou Bei-Hai Li 2005World Journal of Gastroenterology2005,11,30:3
2Identification of small molecule binding molecules by affinity purification using a specific ligand immobilized on PEGA resin显示文摘Kuramochi K Miyano Y Enomoto Y 2008Bioconjugate Chem2008,19,12:1
3Design and Performance of Traveling Wave Tubes Using Field E- mitter Array Cathodes显示文摘Makishima H Miyano S Imura H 1999Appl Surf Sei1999,146,:1
4显示文摘Oshima H Nakamura M Miyano K 2001Phys Rev B2001,63,75:1
5Sibling occurrence of blliary atrssia and biliary dilatation显示文摘 Miyano T Fujimoto T 1996J Pediatr Surg1996,31,9:1
6Reversal of Type 2 diabetes mellitus and improvements in cardiovascular risk factors after surgical weight loss in adolescents 显示文摘Inge TH Miyano G Bean J 2009Pediatrics2009,123,1:1
7Adenine depurination and inactivation of plant ribosomes by an antiviral protein of Mirabilis jalapa(MAP) 显示文摘KATAOKA J HABUKA N MIYANO M 1992Plant Mol Biol1992,20,:1
8Feasibility Study On Steam Injector Driven Jet Pump For Next- Generation Reactor显示文摘Narabayashi T Miyano H Nei H O 1992Int Conference on Advance Nuclear Power Plant1992,36,2:1
9Partial asymmetric syn- thesis of atropisomeric 1, lr-binaphthyls via the ull mann coupling reaction of chiral alcohol esters of 1- bromo-2-naphthoic acid 显示文摘MIYANO S TOBITA M 1990Chemistry letters1990,22,:1
10Molecular composition and regulation of the NOX family NADPH oxidases显示文摘Sumimoto H Miyano K Takeya R 2005Biochem Biophys Res Commun2005,338,1:1
11Interaction of imatinib mesilate with human P-glycoprotein 显示文摘Hamada A Miyano H Watanabe H 2003J Pharmacol Exp Ther2003,307,2:1
12Centro-symmetric technique for measuring shear modulus, viscosity, and surface tension of spread monolayers显示文摘 Miyano K Xu S Q 1983Review of Scientific Instruments1983,54,2:1
13Effects of glycosaminoglycans on the development of in vitro matured and fertilized porcine oocytes to the blastocyst stage in vitro显示文摘Kanok K Miyano T Kota S 1998Biology of Reproduction1998,58,:1
14Proflamin, a new antitu- mor agent, preparation, physicochemical properties and antitumor ac- tivity 显示文摘Ikekawa T Maruyama H Miyano T 1985Jpn J Cancer Res1985,76,2:1
15Association between brachi al-ankle pulse wave velocity and 3 year mortality in community- dwelling older adults显示文摘Miyano I Nishinaga M Takata J 2010hypertension2010,33,7:1
16Identification of small molecule binding molecules by affinity purification using aspecificlig and irmnobilized on PEGA resin 显示文摘KURAMOCHI K MIYANO Y ENOMOTO Y 2008Bioconjug Chem2008,19,12:1
17Effect of caffeine on meiotic maturation of porcine oocytes显示文摘Kren R Ogushi S Miyano T 2004Zygote2004,12,1:1
18Effect of Substrate Bias on Al N Thin Film Preparation in Shielded Reactive Vacuum Arc Deposition显示文摘Takikawa H Kimura K Miyano R 2001Thin Solid Films2001,386,2:1
19Parallel algorithm for refutation tree problem on formal graph systems 显示文摘UCHIDA T SHOUDAI T MIYANO S 1995IEICE Transactions on Information and Systems1995,78,2:1
20Long-term open-hole compression strength of CFRP laminates based on strain invariant failure theo- ry显示文摘Cai H Miyano Y Nakada M 2009Journal of Thermoplastic Composite Materials2009,22,1:1
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