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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Kimuras disease:the CT and MRI characteristics in fifteen cases显示文摘 | Zhang R Ban X H Mo Y X | 2011 | Eur J Radioi2011，80，2： | 1 |
| 3 | Appropriate BMI levels for PCOS patients in Southern China显示文摘 | Chen X Ni R Mo Y | 2010 | Hum Reprod2010，25，5： | 1 |
| 4 | Two-kidney,two clip renalvascular hypertensive rats can be used as stroke-prone rats显示文摘 | Zeng J Zhang Y Mo J Su Z Huang R | 1998 | Stroke1998，29，8： | 1 |
| 5 | 显示文摘 | Mo Y G Dillon R O Snyder P G | 1999 | Thin Solid Films1999，355，： | 1 |
| 6 | 查看详情显示文摘 | MO Y R BAO P GAO J L | | 0，，： | 1 |
| 7 | Silibinin improves palmitate-induced insulin resistance in C2C12 myotubes by attenuating IRS-1/PI3K/Akt pathway inhibition显示文摘 | LI H B YANG Y R MO Z J | 2015 | Braz J Med Biol Res2015，48，5： | 1 |
| 8 | MMSE-based joint source and relay precoding design for amplify-and forward MIMO relay net- works显示文摘 | Mo R H Chew Y H | 2009 | IEEE Transactions on Wireless Communica- tions2009，8，9： | 1 |
| 9 | A nonstationary signal simulation model for continuous wave and pulsed doppler ultrasound显示文摘 | MO L Y L (30BBOLD R S C | 1989 | IEEE Trans Ultrason Ferroelec Freq Contr1989，36，： | 1 |
| 10 | Instant magnetic labeling of tumor cells by ultrasound in vitro显示文摘 | Mo R Y Yang J Wu E X | | 0，，： | 1 |
| 11 | Characterization of human RhCG and mouse Rhcg as novel nonerythmid Rh glycoprotein homologues predominantly expressed in kidney and testis显示文摘 | Liu Z Chen Y Mo R | 2000 | J Biol Chem2000，275，25： | 1 |
| 12 | Optical properties of photochromic organic-inorganic composites显示文摘 | MO Y G DILLON R O SNYDER P G | 1999 | Thin Solid Films1999，3553，： | 1 |
| 13 | Serum immunoreactivity of SMP30 and its tissues expression in hepatocellular carcinoma显示文摘 | Zhou S F Mo F R Bin Y H | 2011 | Clinical Biochemistry2011，44，4： | 1 |
| 14 | Appropriate BMI levels for PCOS patients in Southern China显示文摘 | Chen X Ni R Mo Y | 2010 | Hum Reprod2010，25，5： | 1 |
| 15 | In situ Ru K-edge X-ray absorption fine structure studies of electroprecipitated ruthenium dioxide film with relevance to supercapacitor applications显示文摘 | MO Y ANTONIO M R SCHERSON D A | 2000 | Phys Chem B2000，104，： | 1 |
| 16 | Kimura's disease: The CT and MRI characteristics in fifteen cases显示文摘 | Zhang R Ban X H Mo Y X | 2011 | Eur J Radiol2011，80，2： | 1 |
| 17 | H ydrothermal syntheses and structural diversity of cobalt complexes with 2, 2'-Bibenzimidazole ligand by temperature tuning strategy 显示文摘 | MO H J ZHONG Y R CAO M L | 2009 | Inorg Chem2009，9，1： | 1 |
| 18 | The NCEP/NCAR 40-yeax reanalysis project 显示文摘 | E Kalnay M Kanamitsu R Kistler WCollins D Deaven L Gandin M Iredell S Saha G White J Woollen Y Zhu M Chelliah W Ebisuzaki W Higgins J Janowiak KC Mo C Ropelewski J Wang A Leetmaa R Reynolds R Jenne D Joseph | 1996 | Bulletin of the American Meteorological Society (S0003-0007)1996，77，3： | 1 |
| 19 | Sensitive voltammetric determination of Sudan I in food samples by using gemini surfaetant - ionic liquid- multiwalled carbon nanotube composite film modified glassy carbon electrodes显示文摘 | Mo Z R Zhang Y F Zhao F Q | 2010 | Food Chemistry2010，121，： | 1 |
| 20 | capsule endoscopy for gastrointestinal bleeding with an obscure etiology 显示文摘 | Chao C C Ng Jao Y T Mo L R | 2005 | J Formos Med Assoc2005，104，9： | 1 |
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